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The map label for this gene is atpA [H]

Identifier: 148661096

GI number: 148661096

Start: 1464538

End: 1466187

Strand: Direct

Name: atpA [H]

Synonym: MRA_1316

Alternate gene names: 148661096

Gene position: 1464538-1466187 (Clockwise)

Preceding gene: 148661095

Following gene: 148661097

Centisome position: 33.13

GC content: 62.85

Gene sequence:

>1650_bases
ATGGCTGAGTTGACAATCCCCGCTGATGACATCCAGAGCGCAATCGAAGAGTACGTAAGCTCTTTCACCGCCGACACCAG
TAGAGAGGAAGTCGGTACCGTCGTCGATGCCGGGGACGGCATCGCACACGTCGAGGGTTTGCCATCGGTGATGACCCAAG
AGCTGCTCGAATTCCCGGGCGGAATCCTCGGCGTCGCCCTCAACCTCGACGAGCACAGCGTCGGCGCGGTGATCCTCGGT
GACTTCGAGAACATCGAAGAAGGTCAGCAGGTCAAGCGCACCGGCGAAGTCTTATCGGTTCCGGTTGGCGACGGGTTTTT
GGGGCGGGTGGTTAACCCGCTCGGCCAGCCGATCGACGGGCGCGGAGACGTCGACTCCGATACTCGGCGCGCGCTGGAGC
TCCAGGCGCCCTCGGTGGTGCACCGGCAAGGCGTGAAGGAGCCGTTGCAGACCGGGATCAAGGCGATTGACGCGATGACC
CCGATCGGCCGCGGCCAGCGCCAGCTGATCATCGGCGACCGCAAGACCGGCAAAACCGCCGTCTGCGTCGACACCATCCT
CAACCAGCGGCAGAACTGGGAGTCCGGTGATCCCAAGAAGCAGGTGCGCTGTGTATACGTGGCCATCGGGCAGAAGGGAA
CTACCATCGCCGCGGTACGCCGCACACTGGAAGAGGGCGGTGCGATGGACTACACCACCATCGTCGCGGCCGCGGCGTCG
GAGTCCGCCGGTTTCAAATGGCTTGCGCCGTACACCGGTTCGGCGATCGCCCAGCACTGGATGTACGAGGGCAAGCATGT
GCTGATCATCTTCGACGACCTGACTAAGCAGGCCGAGGCATACCGGGCGATCTCGCTGCTGCTGCGCCGTCCGCCCGGCC
GTGAGGCCTACCCCGGCGATGTGTTCTATCTGCATTCGCGGCTTTTGGAGCGCTGCGCCAAACTGTCCGACGATCTCGGT
GGCGGCTCGCTAACGGGTCTGCCGATCATCGAGACCAAGGCCAACGACATCTCGGCCTACATCCCGACCAACGTCATCTC
GATCACCGACGGGCAATGTTTCCTGGAAACCGACCTGTTCAACCAGGGCGTCCGGCCGGCCATCAACGTCGGTGTGTCGG
TGTCCCGAGTCGGCGGCGCGGCGCAGATCAAGGCTATGAAAGAGGTCGCCGGAAGCCTCCGCTTGGACCTTTCGCAATAC
CGCGAGCTAGAAGCTTTCGCCGCTTTCGCTTCTGATTTGGACGCCGCATCGAAGGCGCAGTTGGAGCGCGGCGCCCGGCT
GGTCGAGCTGCTCAAGCAGCCGCAATCCCAGCCCATGCCCGTTGAGGAGCAAGTGGTTTCGATCTTCCTGGGCACCGGCG
GTCACCTGGACTCGGTGCCCGTCGAGGACGTCCGGCGGTTCGAAACCGAATTACTGGACCACATGCGGGCCTCCGAAGAA
GAGATTTTGACTGAGATCCGGGACAGCCAAAAGCTCACCGAGGAGGCCGCCGACAAGCTCACCGAGGTCATCAAGAACTT
CAAGAAGGGCTTCGCGGCCACCGGTGGCGGCTCTGTGGTGCCCGACGAACATGTCGAGGCCCTCGACGAGGATAAGCTCG
CCAAGGAAGCCGTGAAGGTCAAAAAGCCGGCGCCGAAGAAGAAGAAATAG

Upstream 100 bases:

>100_bases
TCGACGGTACGCTCTCGTCTCGTCTAGCTGCGGCCGAGGCACGACTGCCCGACTGAACCCGAACTAGTCAGCACAAACCG
AAGTAGGAAGACGAAAAGCT

Downstream 100 bases:

>100_bases
CTAACCATGGCTGCCACACTTCGCGAACTACGCGGGCGGATCCGCTCGGCAGGGTCGATCAAAAAGATCACCAAGGCCCA
GGAGCTGATTGCGACATCGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGILGVALNLDEHSVGAVILG
DFENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAAS
ESAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDLG
GGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
RELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEE
EILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKVKKPAPKKKK

Sequences:

>Translated_549_residues
MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGILGVALNLDEHSVGAVILG
DFENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAAS
ESAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDLG
GGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
RELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEE
EILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKVKKPAPKKKK
>Mature_548_residues
AELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGILGVALNLDEHSVGAVILGD
FENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMTP
IGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAASE
SAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDLGG
GSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYR
ELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEEE
ILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKVKKPAPKKKK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=506, Percent_Identity=55.3359683794466, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI4757810, Length=506, Percent_Identity=55.3359683794466, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI19913428, Length=293, Percent_Identity=29.6928327645051, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19913426, Length=293, Percent_Identity=29.0102389078498, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI32189394, Length=490, Percent_Identity=24.8979591836735, Blast_Score=112, Evalue=1e-24,
Organism=Escherichia coli, GI1790172, Length=516, Percent_Identity=50.3875968992248, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1790170, Length=364, Percent_Identity=25.2747252747253, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788251, Length=339, Percent_Identity=26.5486725663717, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=55.9760956175299, Blast_Score=592, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=55.9760956175299, Blast_Score=590, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=51.99203187251, Blast_Score=537, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17510931, Length=328, Percent_Identity=29.2682926829268, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=291, Percent_Identity=28.8659793814433, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=484, Percent_Identity=25.2066115702479, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=54.8707753479125, Blast_Score=567, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6322581, Length=439, Percent_Identity=26.6514806378132, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319603, Length=297, Percent_Identity=28.2828282828283, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24658560, Length=502, Percent_Identity=54.5816733067729, Blast_Score=573, Evalue=1e-163,
Organism=Drosophila melanogaster, GI24638766, Length=463, Percent_Identity=26.5658747300216, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI281361666, Length=302, Percent_Identity=28.476821192053, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24646341, Length=302, Percent_Identity=28.476821192053, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17136796, Length=302, Percent_Identity=28.476821192053, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28574560, Length=411, Percent_Identity=26.2773722627737, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 59289; Mature: 59158

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPG
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCHHHCCCHHHHHHHHHHCCC
GILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDG
CEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCC
RGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTA
CCCCCHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAAS
HHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
ESAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGD
CCCCCEEECCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VFYLHSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLF
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCEEEECCCCEEEEEHHH
NQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDAASKAQ
CCCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
EILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHH
KKPAPKKKK
CCCCCCCCC
>Mature Secondary Structure 
AELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPG
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCHHHCCCHHHHHHHHHHCCC
GILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDG
CEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCC
RGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTA
CCCCCHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAAS
HHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
ESAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGD
CCCCCEEECCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
VFYLHSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLF
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCEEEECCCCEEEEEHHH
NQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDAASKAQ
CCCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
EILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHH
KKPAPKKKK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA