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The map label for this gene is argS

Identifier: 148661080

GI number: 148661080

Start: 1447689

End: 1449341

Strand: Direct

Name: argS

Synonym: MRA_1300

Alternate gene names: 148661080

Gene position: 1447689-1449341 (Clockwise)

Preceding gene: 148661078

Following gene: 148661081

Centisome position: 32.75

GC content: 65.21

Gene sequence:

>1653_bases
GTGACCCCCGCTGACCTGGCTGAGCTGCTCAAAGCGACCGCGGCCGCGGTGCTGGCCGAGCGCGGCCTCGATGCCTCCGC
GTTGCCGCAGATGGTCACGGTGGAACGCCCGCGCATTCCCGAGCACGGCGACTATGCCAGTAACCTGGCGATGCAGCTCG
CCAAGAAAGTCGGCACCAACCCGCGTGAGCTGGCCGGATGGCTTGCCGAGGCACTGACAAAGGTCGACGGTATCGCCTCG
GCGGAGGTGGCCGGGCCGGGCTTTATCAACATGCGGCTGGAAACCGCCGCCCAGGCTAAAGTCGTTACCAGCGTTATCGA
CGCCGGCCACAGCTACGGTCACTCGCTGCTGCTGGCCGGGCGCAAGGTCAACCTGGAATTCGTCTCCGCCAACCCCACCG
GACCGATCCACATCGGCGGTACCCGTTGGGCCGCGGTCGGTGACGCGCTGGGCCGTTTGCTCACCACCCAGGGCGCCGAC
GTGGTCCGCGAATACTATTTCAACGACCACGGCGCCCAGATCGACCGATTCGCCAACTCCCTGATCGCCGCGGCCAAGGG
CGAACCCACGCCCCAAGACGGCTACGCGGGCAGCTACATCACCAACATCGCCGAGCAGGTGCTGCAGAAGGCGCCTGACG
CGCTGAGTCTGCCAGACGCAGAGTTGCGCGAGACCTTCCGCGCAATCGGCGTCGACTTGATGTTCGACCACATCAAACAG
TCTCTGCACGAGTTCGGTACCGACTTCGACGTCTACACCCACGAAGACTCGATGCACACCGGCGGCCGGGTCGAGAACGC
CATCGCCCGACTCCGCGAAACCGGCAACATCTACGAGAAGGACGGCGCAACCTGGTTGCGCACCAGCGCATTTGGTGACG
ACAAGGACCGCGTCGTGATCAAGAGCGACGGCAAACCGGCATATATCGCCGGTGATCTCGCCTACTACTTGGACAAACGC
CAACGCGGTTTTGACTTGTGCATCTACATGCTCGGCGCCGACCATCACGGCTACATCGCCCGGCTAAAGGCCGCGGCCGC
CGCCTTCGGTGACGACCCGGCCACCGTCGAGGTGCTCATTGGGCAGATGGTGAACCTGGTCCGCGACGGCCAACCGGTCC
GGATGAGCAAACGTGCAGGCACCGTGCTCACCCTCGACGACCTGGTCGAGGCGATCGGCGTGGACGCCGCACGTTACAGC
CTGATCCGCTCCTCGGTGGACACCGCGATCGACATCGACCTGGCGCTATGGTCCTCGGCGTCGAACGAAAACCCGGTCTA
TTACGTGCAATACGCGCATGCCCGGCTCTCAGCGCTGGCTCGCAACGCCGCCGAACTCGCCCTGATCCCGGATACAAACC
ACCTCGAACTGCTTAACCACGACAAGGAGGGCACGCTGCTGCGCACCCTCGGCGAATTCCCGAGGGTGCTCGAGACCGCG
GCCTCCCTGCGGGAACCGCACCGGGTCTGCCGCTACCTGGAAGACCTGGCCGGCGACTATCACCGGTTCTACGACTCGTG
CCGAGTGTTGCCGCAAGGCGACGAGCAGCCCACCGACCTGCACACCGCGCGCCTAGCGTTGTGCCAGGCCACCCGTCAGG
TCATCGCCAACGGGCTGGCGATCATCGGCGTCACCGCACCGGAGCGAATGTGA

Upstream 100 bases:

>100_bases
TTGCGCCATGGGGCCCCGCCAGAGTAGCGCATCGCGGCTACCCACTGACCACCGCAACGGATTCGAAGCCCAACCACCTC
AGCCCATAGGATGGACGTTC

Downstream 100 bases:

>100_bases
ACGAGCTGCTGCACTTAGCGCCGAATGTGTGGCCGCGCAATACTACTCGCGATGAAGTCGGTGTGGTCTGCATCGCAGGA
ATTCCACTGACGCAGCTCGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIAS
AEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAGRKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGAD
VVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQ
SLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKR
QRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYS
LIRSSVDTAIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETA
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM

Sequences:

>Translated_550_residues
MTPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIAS
AEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAGRKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGAD
VVREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQ
SLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKR
QRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYS
LIRSSVDTAIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETA
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM
>Mature_549_residues
TPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTNPRELAGWLAEALTKVDGIASA
EVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAGRKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGADV
VREYYFNDHGAQIDRFANSLIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQS
LHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQ
RGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYSL
IRSSVDTAIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETAA
SLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAIIGVTAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=567, Percent_Identity=26.1022927689594, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1788184, Length=573, Percent_Identity=26.8760907504363, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6320548, Length=543, Percent_Identity=26.7034990791897, Blast_Score=140, Evalue=7e-34,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MYCBO (P67570)

Other databases:

- EMBL:   BX248338
- RefSeq:   NP_854978.1
- ProteinModelPortal:   P67570
- EnsemblBacteria:   EBMYCT00000016571
- GeneID:   1092089
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1324
- GeneTree:   EBGT00050000016532
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   MBOV233413:MB1324-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 59710; Mature: 59579

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTN
CCHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PRELAGWLAEALTKVDGIASAEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAG
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCHHCCCEEEEEC
RKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGADVVREYYFNDHGAQIDRFANS
CEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
LIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQ
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCEEEE
KSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLI
ECCCCCEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHH
GQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYSLIRSSVDTAIDIDLALWSSA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHHCCHHEEEEHEEECCC
SNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETA
CCCCCEEEEEEHHHHHHHHHCCCCCEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
IIGVTAPERM
EEEECCCCCC
>Mature Secondary Structure 
TPADLAELLKATAAAVLAERGLDASALPQMVTVERPRIPEHGDYASNLAMQLAKKVGTN
CHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PRELAGWLAEALTKVDGIASAEVAGPGFINMRLETAAQAKVVTSVIDAGHSYGHSLLLAG
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCHHCCCEEEEEC
RKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLTTQGADVVREYYFNDHGAQIDRFANS
CEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
LIAAAKGEPTPQDGYAGSYITNIAEQVLQKAPDALSLPDAELRETFRAIGVDLMFDHIKQ
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLHEFGTDFDVYTHEDSMHTGGRVENAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCEEEE
KSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPATVEVLI
ECCCCCEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHH
GQMVNLVRDGQPVRMSKRAGTVLTLDDLVEAIGVDAARYSLIRSSVDTAIDIDLALWSSA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHHCCHHEEEEHEEECCC
SNENPVYYVQYAHARLSALARNAAELALIPDTNHLELLNHDKEGTLLRTLGEFPRVLETA
CCCCCEEEEEEHHHHHHHHHCCCCCEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
ASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
IIGVTAPERM
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972