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The map label for this gene is ppe12

Identifier: 148660531

GI number: 148660531

Start: 849409

End: 851346

Strand: Reverse

Name: ppe12

Synonym: MRA_0764

Alternate gene names: 148660531

Gene position: 851346-849409 (Counterclockwise)

Preceding gene: 148660532

Following gene: 148660529

Centisome position: 19.26

GC content: 58.62

Gene sequence:

>1938_bases
ATGGTCGGTTTCGCGTGGTTGCCTCCGGAGACCAATTCGCTACGGATGTATCTGGGTGCGGGGTCACGGCCACTATTGGC
GGCGGCGGGGGCCTGGGACGGGTTGGCCGAGGAGTTGCACGCGGCGGCGTCGTCGTTCGGGTCGGTGACGTCGGAGTTGG
CCGGCGGCGCTTGGCAGGGACCGGCGTCGGCCGCGATGGCGAATGCCGCGGGGCCGTATGCGAGCTGGTTGACCGCGGCT
GGAGCCCAGGCCGAGCTGGCAGCGCGGCAGGCTCGGGCGGCGGCGGGTGCATTTGAGGAGGCGCTGGCCGGCGTGGTGCA
TCCGGCGGTGGTGCAGGCCAATCGTGTTCGGACGTGGTTGTTGGCGGTGTCGAATGTGTTCGGGCAAAACGCGCCGGCCA
TAGCGGCCATGGAATCCACCTACGAGCAGATGTGGGCACAAGACGTGGCGGTGATGGCCGGCTACCATGCCGCATCCTCG
GCGGCAGCGGCACAGCTGGCGTCGTGGCAGCCGGCGTTGCCAAACATCAATTTGGGTGTCGGCAATATCGGCAACCTCAA
TGTCGGCAATGGTAATACCGGCGATTACAACCTGGGTAATGGAAACCTCGGTAACGCCAACTTTGGCGGCGGAAACGGAA
GCGCCTTCCACGGCCAGATTTCCAGCTTCAACGTGGGTAGCGGCAACATCGGCAACTTCAACCTGGGTAGCGGAAACGGA
AACGTTGGCATCGGACCGTCCAGCTTTAACGTGGGTAGCGGCAACATCGGTAATGCGAACGTCGGGGGTGGCAACTCTGG
CGACAACAACTTCGGCTTCGGGAACTTTGGCAATGCCAACATTGGTATCGGAAATGCAGGTCCAAACATGAGTTCCCCCG
CCGTGCCCACCCCCGGCAATGGGAATGTCGGGATTGGCAACGGTGGCAATGGAAACTTCGGCGGTGGTAACACGGGCAAC
GCAAATATCGGTCTGGGAAACGTAGGCGACGGCAACGTTGGCTTCGGGAACAGCGGCAGCTACAACTTCGGCTTCGGGAA
CACCGGCAACAATAATATCGGCATTGGGTTAACCGGCAGCAATCAGATCGGCTTTGGCGGACTGAATTCCGGTAGCGGTA
ATATAGGATTTGGTAACTCGGGCACCGGGAACATCGGCTTCTTCAACTCGGGCAGCGGCAACTTCGGCGTGGGCAACTCG
GGCGTCACCAACACGGGCGTAGCCAACTCAGGCAACATCAACACCGGCTTCGGAAACTCCGGCTTTATCAACACCGGCTT
CGGGAACGCGTTAAGCGTCAACACTGGCTTTGGCAACTCAGGTCAGGCCAATACCGGCATAGGGAACGCGGGCGATTTCA
ACACCGGCAACTTCAACGGCGGCATCATTAACACCGGTAGCTTCAACTCGGGTGCATTCAACTCAGGCAGCTTCAACGGA
GGAGACGCTAATTCTGGTTTCTTGAACTCTGGCCTGACGAACACCGGCTTCGCAAATTCTGGCAATATCAACACGGGCGG
CTTTAACGCGGGCAACCTGAACACCGGTTTCGGCAATACTACCGATGGGCTGGGCGAAAACTCGGGATTCGGAAACGCCG
GCAGTGGAAATTCGGGTTTCAATAATTCTGGTAGGGGAAACTCCGGCGCCCAAAACGTTGGTAATTTACAAATCTCGGGC
TTCGCCAACTCGGGCCAATCGGTAACGGGTTACAACAATTCGGTTAGTGTAACATCGGGTTTCGGGAACAAGGGAACCGG
CCTGTTCAGTGGATTCATGTCGGGCTTTGGCAATACGGGTTTTCTACAGTCGGGCTTCGGTAATCTTGAAGCCAATCCCG
ACAACAACAGCGCCACATCGGGTTTCGGGAACTCTGGAAAGCAGGATTCTGGTGGCTTTAATTCGATCGATTTCGTGTCG
GGCTTTTTCCACCGCTAG

Upstream 100 bases:

>100_bases
CCAGTGCACGCGGCGCAATTCCGATAGAAGTCCCAATCCCTTCGCGTTGTGTAGTTAGGCTCGAGGCGTCCTGGTTTGTC
AATGGTGTGAGGGGGCCGTG

Downstream 100 bases:

>100_bases
CTAACACTAGCCCGGTATCGTCCCGGCGACCGGGTCCGGCGTACGCCGTACCCGGAGGCAATCCGATCTGGATGTCCCAT
GCACGGCCGAGCAGGTTCCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQGPASAAMANAAGPYASWLTAA
GAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWLLAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASS
AAAAQLASWQPALPNINLGVGNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNG
NVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGNGNVGIGNGGNGNFGGGNTGN
ANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGSNQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNS
GVTNTGVANSGNINTGFGNSGFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNG
GDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGFNNSGRGNSGAQNVGNLQISG
FANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTGFLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVS
GFFHR

Sequences:

>Translated_645_residues
MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQGPASAAMANAAGPYASWLTAA
GAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWLLAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASS
AAAAQLASWQPALPNINLGVGNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNG
NVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGNGNVGIGNGGNGNFGGGNTGN
ANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGSNQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNS
GVTNTGVANSGNINTGFGNSGFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNG
GDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGFNNSGRGNSGAQNVGNLQISG
FANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTGFLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVS
GFFHR
>Mature_645_residues
MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQGPASAAMANAAGPYASWLTAA
GAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWLLAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASS
AAAAQLASWQPALPNINLGVGNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNG
NVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGNGNVGIGNGGNGNFGGGNTGN
ANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGSNQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNS
GVTNTGVANSGNINTGFGNSGFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNG
GDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGFNNSGRGNSGAQNVGNLQISG
FANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTGFLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVS
GFFHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

Organism=Drosophila melanogaster, GI21357785, Length=112, Percent_Identity=40.1785714285714, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE12_MYCTU (Q79FW4)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   F70825
- RefSeq:   NP_335206.1
- RefSeq:   YP_177753.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FW4
- SMR:   Q79FW4
- EnsemblBacteria:   EBMYCT00000000823
- EnsemblBacteria:   EBMYCT00000069826
- GeneID:   888708
- GeneID:   926080
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0779
- KEGG:   mtu:Rv0755c
- TIGR:   MT0779
- TubercuList:   Rv0755c
- GeneTree:   EBGT00050000014886
- HOGENOM:   HBG572308
- ProtClustDB:   CLSK799739
- GO:   GO:0040007
- InterPro:   IPR002989
- InterPro:   IPR000030

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE

EC number: NA

Molecular weight: Translated: 62693; Mature: 62693

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQG
CCCEEECCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PASAAMANAAGPYASWLTAAGAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWL
CHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASSAAAAQLASWQPALPNINLGV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
GNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNG
CCCCCEECCCCCCCCEECCCCCCCCCCCCCCCCCEEECCCCEEECCCCCCCCEECCCCCC
NVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGN
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
GNVGIGNGGNGNFGGGNTGNANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGS
CCEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
NQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNSGVTNTGVANSGNINTGFGNS
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNG
CCEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
GDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGF
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NNSGRGNSGAQNVGNLQISGFANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTG
CCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
FLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVSGFFHR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQG
CCCEEECCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PASAAMANAAGPYASWLTAAGAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWL
CHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASSAAAAQLASWQPALPNINLGV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
GNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNG
CCCCCEECCCCCCCCEECCCCCCCCCCCCCCCCCEEECCCCEEECCCCCCCCEECCCCCC
NVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGN
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
GNVGIGNGGNGNFGGGNTGNANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGS
CCEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
NQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNSGVTNTGVANSGNINTGFGNS
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNG
CCEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
GDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGF
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NNSGRGNSGAQNVGNLQISGFANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTG
CCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
FLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVSGFFHR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036