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The map label for this gene is PE_PGRS35 [H]

Identifier: 148660521

GI number: 148660521

Start: 837007

End: 839358

Strand: Direct

Name: PE_PGRS35 [H]

Synonym: MRA_0754

Alternate gene names: 148660521

Gene position: 837007-839358 (Clockwise)

Preceding gene: 148660518

Following gene: 148660522

Centisome position: 18.94

GC content: 79.21

Gene sequence:

>2352_bases
ATGTCGTTCGTGCTGGCGATGCCGGAGGTGTTGGGGTCGGCGGCAACGGATCTGGCCGCTCTGGGCTCGGTGCTGGGCGC
GGCCGATGCGGCCGCGGCGGCTACGACGACGGGCATCGTGGCCGCGGCCCAGGATGAGGTGTCGGCGGCGATCGCGGCGT
TGTTTTCCGCCCACGGCCGGGCCTATCAGGTGGCCAGTGCGCAGGCGGCGGCGGTTCACGCCCAGTTCGTGGAGGCGTTG
AGCGCGGGTGCGGGGGCCTACGCCAGCGCGGAGGCCGCCGGCGCGGCGGTGCTGGCCAACCCGGCGCAGAGCGTGCAGCA
GGACCTGCTGGCCGCCGTCAATGCGCAAAGTGTCGCGCTCACGGGGCGCCCGTTGATCGGCAACGGCGCCAACGGGGCCC
CGGGCACGGGGGCCAATGGTGCGCCGGGCGGGTGGTTGCTCGGTAATGGTGGGGCCGGCGGGTCCGCCGCCGCTGGCTCG
GGCCTGCCCGGCGGGGCCGGCGGGGCCGCCGGGTTGTTCGGCACCGGCGGGGCTGGTGGGGCCGGCGGGAGTTCCACGGT
AGGTGATGGCGGGGCCGGGGGTGCCGGTGGGTCAGGTGGCTGGTTGTTGGGCACCGGTGGGGTCGGCGGGGTCGGCGGGC
TCGGGGCCGGCGCCGGTGGGGCCGGCGGGGTTGGTGGGGCCGGCGGGCTGTTGGGTGCTGGCGGGCACGGCGGCGCCGGC
GGGCTCGGCGCCGTCACCGGTGGGGTCGGGGGAGCTGGCGGAGCCGGTGGGCTGCTGGCCGGGCTGCTGGCCGGGCCGGG
CGGGGCCGGCGGGACCGGCGGACGTGGCTTTCTCAACGACGGTGGGGTCGGTGGGGCTGGCGGCAACGCCGGGCTGCTGT
TCGGTGCCGGCGGCACCGGTGGATCCGGCGGAGCCGGCCTAGGTGGTGACGGTGGGGCCGGTGGGGCCGGCGGCAACGCC
GGTGTGCTGTTCGGCAACGCCGGATCCGGGGGGACCGGCGGGTTCGGCGATACCGACGGGGGAGCCGGCGGTGCCGGCGG
TGACGCCGGCTGGTTGGGCTCCGGTGGGGTCGGCGGGGCCGGCGGGTTCGGCGAAACCGGTGACGGGGGTGTCGGCGGGG
CCGGCGGCAAGGCCGGGTTGCTGATCGGTAACGGCGGGGCCGGCGGCGCCGGTGGGCAAGGCGCCGTGACCGGCGGTACC
GGCGGGGCCGGCGGCGACGGGGTGCTGATCGGCAACGGCGGCAACGCCGGCATCGGCGGAACCGGACCGACCGCGGGTGA
TACCGGCGCGGGTGGGATCAGTGGGCTGCTGCTGGGCGCCGACGGCTTCAACGCCCCGGCCAGCGCCTCTCCGCTGCACA
CCCTGAAACAACAGGCGCTGGCCGCGATCAACGCGCCGACCCAGACACTGACCGGGCGACCGCTGATCGGCAACGGCACC
CCCGGGGCGGTCGGCAGCGGGGCCACCGGGGCCCCCGGTGGGTGGCTGCTCGGCGACGGCGGGGCCGGCGGGTCCGGCGC
GGCGGGCTCGGGCGCGCCCGGCGGGGCGGGCGGGGCTGCCGGGCTGTGGGGTACCGGCGGGGCCGGCGGGGCCGGAGGCA
GCTCGGCGGGTGGCGGCGGGGCCGGTGGGGCCGGCGGGGCCGGCGGCTGGCTGCTCGGCGACGGCGGGGCCGGCGGGATC
GGCGGAGCCAGCACCGTACTCGGCGGCACCGGCGGGGGAGGCGGGGTCGGTGGGCTGTGGGGCGCCGGTGGGGCCGGCGG
GGCCGGTGGAACCGGCCTTGTTGGTGGCGACGGCGGGGCCGGTGGGGCCGGCGGGACCGGCGGACTGCTGGCCGGGCTGA
TCGGTGCCGGCGGAGGTCACGGCGGGACCGGCGGGCTCAGCACTAATGGCGACGGCGGGGTTGGCGGGGCCGGCGGGAAT
GCCGGAATGCTCGCCGGGCCGGGCGGCGCCGGCGGAGCCGGCGGTGACGGCGAAAACCTGGACACCGGTGGGGACGGCGG
GGCCGGCGGTAGCGCAGGGCTGCTGTTCGGCAGCGGCGGCGCCGGCGGCGCCGGCGGATTTGGTTTCCTCGGTGGGGACG
GCGGGGCCGGTGGCAACGCCGGGCTGCTGTTGTCCAGCGGCGGGGCCGGCGGGTTCGGCGGGTTCGGCACCGCCGGTGGG
GTCGGTGGGGCCGGCGGCAATGCCGGCTGGCTGGGCTTCGGCGGGGCCGGTGGCGTCGGCGGCAGCGCCGGGCTGATCGG
CACCGGCGGCAACGGCGGCAACGGCGGCACCGGCGCCAACGCCGGCAGCCCCGGAACCGGCGGCGCCGGCGGGTTGCTGC
TGGGCCAAAACGGGCTCAACGGGTTGCCGTAG

Upstream 100 bases:

>100_bases
TCGTCTTCGACGATGCGGTGTACTTGTCATCAGAATCAGTGTCTATGGTCATCGGGGGTGTCGTGGGCGCTGGCCCGCTG
ACTCGGGTGGGAGGTGGCAC

Downstream 100 bases:

>100_bases
CCGGGCGGCACGGCATGGCTTCCGGGCGTCAACCACTCGCCGGTGATGCAGATCGGCTGCGGAGCGGGCCGCCAAAATGG
GGGCCGCCGCGCCAGGTATC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MSFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEAL
SAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGS
GLPGGAGGAAGLFGTGGAGGAGGSSTVGDGGAGGAGGSGGWLLGTGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAG
GLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAGLLFGAGGTGGSGGAGLGGDGGAGGAGGNA
GVLFGNAGSGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGAGGFGETGDGGVGGAGGKAGLLIGNGGAGGAGGQGAVTGGT
GGAGGDGVLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGT
PGAVGSGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGSSAGGGGAGGAGGAGGWLLGDGGAGGI
GGASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGGLSTNGDGGVGGAGGN
AGMLAGPGGAGGAGGDGENLDTGGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGG
VGGAGGNAGWLGFGGAGGVGGSAGLIGTGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP

Sequences:

>Translated_783_residues
MSFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEAL
SAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGS
GLPGGAGGAAGLFGTGGAGGAGGSSTVGDGGAGGAGGSGGWLLGTGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAG
GLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAGLLFGAGGTGGSGGAGLGGDGGAGGAGGNA
GVLFGNAGSGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGAGGFGETGDGGVGGAGGKAGLLIGNGGAGGAGGQGAVTGGT
GGAGGDGVLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGT
PGAVGSGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGSSAGGGGAGGAGGAGGWLLGDGGAGGI
GGASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGGLSTNGDGGVGGAGGN
AGMLAGPGGAGGAGGDGENLDTGGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGG
VGGAGGNAGWLGFGGAGGVGGSAGLIGTGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP
>Mature_782_residues
SFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALS
AGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGSG
LPGGAGGAAGLFGTGGAGGAGGSSTVGDGGAGGAGGSGGWLLGTGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAGG
LGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAGLLFGAGGTGGSGGAGLGGDGGAGGAGGNAG
VLFGNAGSGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGAGGFGETGDGGVGGAGGKAGLLIGNGGAGGAGGQGAVTGGTG
GAGGDGVLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTP
GAVGSGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGSSAGGGGAGGAGGAGGWLLGDGGAGGIG
GASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGGLSTNGDGGVGGAGGNA
GMLAGPGGAGGAGGDGENLDTGGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGGV
GGAGGNAGWLGFGGAGGVGGSAGLIGTGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 63998; Mature: 63866

Theoretical pI: Translated: 3.78; Mature: 3.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGR
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHCCC
AYQVASAQAAAVHAQFVEALSAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVAL
EEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEECCHHHHHHHHHHHHCCCEEEE
TGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGSGLPGGAGGAAGLFGTGGAGG
ECCCEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGSSTVGDGGAGGAGGSGGWLLGTGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAG
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAGLLFGAGGTG
CHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
GSGGAGLGGDGGAGGAGGNAGVLFGNAGSGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGFGETGDGGVGGAGGKAGLLIGNGGAGGAGGQGAVTGGTGGAGGDGVLIGNGGNAGIGG
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCC
TGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGT
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCCEECCCC
PGAVGSGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGSSAGGGG
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGAGGAGGWLLGDGGAGGIGGASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGA
CCCCCCCCCEEEECCCCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCC
GGAGGTGGLLAGLIGAGGGHGGTGGLSTNGDGGVGGAGGNAGMLAGPGGAGGAGGDGENL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
DTGGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGG
CCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCC
VGGAGGNAGWLGFGGAGGVGGSAGLIGTGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLN
CCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
GLP
CCC
>Mature Secondary Structure 
SFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGR
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHCCC
AYQVASAQAAAVHAQFVEALSAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVAL
EEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEECCHHHHHHHHHHHHCCCEEEE
TGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGSGLPGGAGGAAGLFGTGGAGG
ECCCEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGSSTVGDGGAGGAGGSGGWLLGTGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAG
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAGLLFGAGGTG
CHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
GSGGAGLGGDGGAGGAGGNAGVLFGNAGSGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGFGETGDGGVGGAGGKAGLLIGNGGAGGAGGQGAVTGGTGGAGGDGVLIGNGGNAGIGG
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCC
TGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGT
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCCEECCCC
PGAVGSGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGSSAGGGG
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGGAGGAGGWLLGDGGAGGIGGASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGA
CCCCCCCCCEEEECCCCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCC
GGAGGTGGLLAGLIGAGGGHGGTGGLSTNGDGGVGGAGGNAGMLAGPGGAGGAGGDGENL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
DTGGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGG
CCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCC
VGGAGGNAGWLGFGGAGGVGGSAGLIGTGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLN
CCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
GLP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]