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The map label for this gene is nusG

Identifier: 148660413

GI number: 148660413

Start: 735560

End: 736276

Strand: Direct

Name: nusG

Synonym: MRA_0650

Alternate gene names: 148660413

Gene position: 735560-736276 (Clockwise)

Preceding gene: 148660412

Following gene: 148660414

Centisome position: 16.64

GC content: 63.88

Gene sequence:

>717_bases
GTGACTACCTTCGACGGTGACACGTCCGCGGGTGAGGCGGTCGATCTAACAGAGGCCAACGCCTTCCAGGATGCAGCGGC
CCCGGCTGAAGAGGTCGATCCGGCCGCCGCGCTCAAAGCGGAGCTGCGCAGCAAGCCCGGCGACTGGTACGTCGTTCACT
CCTACGCAGGGTACGAGAACAAGGTCAAGGCCAACCTGGAAACCCGGGTGCAGAACCTTGATGTCGGCGACTACATCTTC
CAGGTGGAGGTGCCCACCGAAGAGGTCACCGAGATCAAAAACGGCCAACGCAAGCAGGTCAACCGTAAGGTGCTGCCCGG
CTACATTCTGGTGCGGATGGACTTGACCGACGACTCCTGGGCCGCGGTGCGTAACACGCCGGGGGTCACGGGGTTCGTTG
GGGCAACATCTCGCCCGTCAGCGCTCGCCCTCGACGACGTGGTGAAGTTTCTGCTTCCGCGGGGGTCGACGAGGAAGGCT
GCCAAGGGTGCGGCCAGCACGGCTGCCGCCGCCGAGGCGGGCGGGCTAGAGCGTCCGGTCGTCGAGGTCGACTACGAGGT
GGGCGAATCGGTAACCGTCATGGACGGGCCGTTTGCCACATTGCCGGCCACGATCAGCGAGGTCAACGCCGAACAGCAGA
AACTCAAGGTGCTGGTCTCCATCTTCGGCCGCGAAACACCGGTGGAGCTGACCTTTGGCCAAGTCTCCAAGATCTAG

Upstream 100 bases:

>100_bases
TTCATGGTGGCGCTGGTCGCCGGTGCTGACTTGGGCCTGACCAAGCTGGTGATGTTGGTGTTCGGCTGAGGCTCGAGAGT
GACAGAGAGGACTGAAAACC

Downstream 100 bases:

>100_bases
CCCAGCAGGGCAGGCCACACAGGCTGAAACAAGGAAGGACATCGACACGTCATGGCCCCGAAGAAGAAGGTCGCCGGGTT
GATCAAGCTGCAGATCGTGG

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTTFDGDTSAGEAVDLTEANAFQDAAAPAEEVDPAAALKAELRSKPGDWYVVHSYAGYENKVKANLETRVQNLDVGDYIF
QVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPRGSTRKA
AKGAASTAAAAEAGGLERPVVEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFGQVSKI

Sequences:

>Translated_238_residues
MTTFDGDTSAGEAVDLTEANAFQDAAAPAEEVDPAAALKAELRSKPGDWYVVHSYAGYENKVKANLETRVQNLDVGDYIF
QVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPRGSTRKA
AKGAASTAAAAEAGGLERPVVEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFGQVSKI
>Mature_237_residues
TTFDGDTSAGEAVDLTEANAFQDAAAPAEEVDPAAALKAELRSKPGDWYVVHSYAGYENKVKANLETRVQNLDVGDYIFQ
VEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPRGSTRKAA
KGAASTAAAAEAGGLERPVVEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFGQVSKI

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nusG family

Homologues:

Organism=Escherichia coli, GI1790414, Length=190, Percent_Identity=42.1052631578947, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_MYCBO (P65590)

Other databases:

- EMBL:   BX248336
- RefSeq:   NP_854316.1
- ProteinModelPortal:   P65590
- SMR:   P65590
- EnsemblBacteria:   EBMYCT00000017580
- GeneID:   1091767
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0658
- GeneTree:   EBGT00050000017483
- HOGENOM:   HBG751162
- OMA:   ENRVKAN
- ProtClustDB:   PRK05609
- BioCyc:   MBOV233413:MB0658-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 25447; Mature: 25316

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFDGDTSAGEAVDLTEANAFQDAAAPAEEVDPAAALKAELRSKPGDWYVVHSYAGYEN
CCCCCCCCCCCCEEECCCCCCHHHHCCCHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCC
KVKANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSW
EEECCHHHHHHCCCCCCEEEEEECCHHHHHHHHCCHHHHHCCCCCCCEEEEEEECCCCCC
AAVRNTPGVTGFVGATSRPSALALDDVVKFLLPRGSTRKAAKGAASTAAAAEAGGLERPV
HHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHCCCCCCCE
VEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFGQVSKI
EEEECCCCCEEEEECCCCHHCCHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TTFDGDTSAGEAVDLTEANAFQDAAAPAEEVDPAAALKAELRSKPGDWYVVHSYAGYEN
CCCCCCCCCCCEEECCCCCCHHHHCCCHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCC
KVKANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSW
EEECCHHHHHHCCCCCCEEEEEECCHHHHHHHHCCHHHHHCCCCCCCEEEEEEECCCCCC
AAVRNTPGVTGFVGATSRPSALALDDVVKFLLPRGSTRKAAKGAASTAAAAEAGGLERPV
HHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHCCCCCCCE
VEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFGQVSKI
EEEECCCCCEEEEECCCCHHCCHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972