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The map label for this gene is 148660343

Identifier: 148660343

GI number: 148660343

Start: 668562

End: 669704

Strand: Reverse

Name: 148660343

Synonym: MRA_0581

Alternate gene names: NA

Gene position: 669704-668562 (Counterclockwise)

Preceding gene: 148660344

Following gene: 148660342

Centisome position: 15.15

GC content: 64.92

Gene sequence:

>1143_bases
GTGGCTGGCAATCCTGATGTGGTGACGGTGCTGCTGGGCGGTGACGTCATGCTCGGCCGTGGCGTCGATCAGATCCTGCC
TCATCCCGGCAAACCGCAATTGCGCGAACGGTATATGCGGGATGCGACCGGCTATGTTCGCCTGGCCGAGCGGGTGAACG
GGCGCATTCCGCTCCCCGTGGATTGGCGCTGGCCCTGGGGCGAGGCGTTGGCGGTCCTTGAGAACACCGCGACCGACGTC
TGTTTGATCAATCTGGAGACGACGATCACCGCCGACGGTGAATTCGCCGACCGCAAACCGGTCTGCTACCGGATGCACCC
GGATAACGTGCCGGCGCTGACGGCATTGCGGCCGCACGTGTGCGCGCTGGCCAACAACCACATTCTCGATTTCGGCTACC
AGGGGCTGACCGATACGGTCGCGGCTCTCGCCGGTGCGGGGATCCAGAGTGTCGGGGCGGGAGCCGATTTGCTCGCCGCT
CGCCGCTCGGCGCTAGTCACGGTTGGCCATGAACGCCGGGTGATCGTCGGCTCGGTAGCGGCGGAATCCAGCGGCGTCCC
CGAATCCTGGGCCGCCCGCCGCGACCGGCCCGGAGTGTGGTTGATCCGGGATCCGGCGCAACGCGACGTCGCCGACGATG
TGGCGGCACAGGTGCTGGCGGACAAACGCCCCGGCGATATCGCCATAGTCTCGATGCATTGGGGATCCAATTGGGGCTAT
GCGACCGCACCCGGCGACGTCGCGTTCGCGCACCGACTGATCGACGCCGGCATCGACATGGTCCACGGACATTCCTCGCA
CCATCCGCGGCCAATCGAGATATATCGCGGTAAACCGATCCTGTACGGATGCGGTGACGTCGTTGACGACTACGAAGGCA
TCGGCGGGCACGAGTCGTTCCGCAGTGAACTGCGACTGCTGTATCTGACCGTCACCGATCCCGCCAGCGGGAACCTGATC
TCGCTGCAGATGCTTCCACTGCGAGTGTCGCGGATGCGCCTACAGCGTGCCTCCCAGACCGACACCGAATGGCTCCGCAA
CACCATTGAGCGCATCAGCCGCCGGTTCGGGATTCGAGTCGTGACTCGACCCGACAACCTGCTGGAGGTCGTTCCCGCTG
CCAACCTAACGAGCAAGGAGTAA

Upstream 100 bases:

>100_bases
GGCCCCACCCACGAGGCCGCCGCCGGCCGATCGTATGACGTGCAATGTACGCCATAGGGTGCGTGTTACGGCGATTACCT
GAAGGCGGCGGTGGTCCGGA

Downstream 100 bases:

>100_bases
CCGGCAACCATGGCGATCCGCCAACACGTCGGCGCGCTGTTCACCGACCTGTACGAGGTGACGATGGCCCAGGCCTACTG
GGCCGAAAGAATGTCGGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDV
CLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAA
RRSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGY
ATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLI
SLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE

Sequences:

>Translated_380_residues
MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDV
CLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAA
RRSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGY
ATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLI
SLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE
>Mature_379_residues
AGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPVDWRWPWGEALAVLENTATDVC
LINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHVCALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAAR
RSALVTVGHERRVIVGSVAAESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGYA
TAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESFRSELRLLYLTVTDPASGNLIS
LQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRVVTRPDNLLEVVPAANLTSKE

Specific function: Could be involved in the biosynthesis of a cell wall component (Potential)

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y0574_MYCTU (O53771)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842573
- PIR:   E70933
- RefSeq:   NP_215088.1
- RefSeq:   NP_335011.1
- ProteinModelPortal:   O53771
- EnsemblBacteria:   EBMYCT00000002911
- EnsemblBacteria:   EBMYCT00000071162
- GeneID:   887721
- GeneID:   924995
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0602
- KEGG:   mtu:Rv0574c
- TIGR:   MT0602
- TubercuList:   Rv0574c
- GeneTree:   EBGT00070000032274
- HOGENOM:   HBG491896
- OMA:   MTGRGID
- ProtClustDB:   CLSK871828
- InterPro:   IPR019079
- SMART:   SM00854

Pfam domain/function: PF09587 PGA_cap

EC number: NA

Molecular weight: Translated: 41548; Mature: 41417

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPV
CCCCCCEEEEEECCCEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHV
CCCCCHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCEEHHCCCHH
CALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVA
HHHCCCCEEECCCCCHHHHHHHHHCCCHHHCCCCHHHHHHCCCEEEEECCCCEEEEEEEE
AESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGY
CCCCCCCHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCE
ATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESF
ECCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCCEEEEECCCHHHHHCCCCCHHHH
RSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRV
HCCEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEE
VTRPDNLLEVVPAANLTSKE
EECCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
AGNPDVVTVLLGGDVMLGRGVDQILPHPGKPQLRERYMRDATGYVRLAERVNGRIPLPV
CCCCCEEEEEECCCEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DWRWPWGEALAVLENTATDVCLINLETTITADGEFADRKPVCYRMHPDNVPALTALRPHV
CCCCCHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCEEHHCCCHH
CALANNHILDFGYQGLTDTVAALAGAGIQSVGAGADLLAARRSALVTVGHERRVIVGSVA
HHHCCCCEEECCCCCHHHHHHHHHCCCHHHCCCCHHHHHHCCCEEEEECCCCEEEEEEEE
AESSGVPESWAARRDRPGVWLIRDPAQRDVADDVAAQVLADKRPGDIAIVSMHWGSNWGY
CCCCCCCHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCE
ATAPGDVAFAHRLIDAGIDMVHGHSSHHPRPIEIYRGKPILYGCGDVVDDYEGIGGHESF
ECCCCHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCCEEEEECCCHHHHHCCCCCHHHH
RSELRLLYLTVTDPASGNLISLQMLPLRVSRMRLQRASQTDTEWLRNTIERISRRFGIRV
HCCEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCEEE
VTRPDNLLEVVPAANLTSKE
EECCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036