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The map label for this gene is 148660340

Identifier: 148660340

GI number: 148660340

Start: 664797

End: 666128

Strand: Reverse

Name: 148660340

Synonym: MRA_0578

Alternate gene names: NA

Gene position: 666128-664797 (Counterclockwise)

Preceding gene: 148660341

Following gene: 148660335

Centisome position: 15.07

GC content: 66.52

Gene sequence:

>1332_bases
ATGAAGCTCTTTGACGATCGTGGCGACGCTGGACGCCAGTTGGCGCAACGCCTGGCGCAGCTATCCGGCAAGGCCGTCGT
CGTCCTTGGCTTGCCGCGCGGCGGGGTACCGGTGGCCTTTGAGGTCGCCAAGTCACTGCAAGCGCCACTCGACGTCCTGG
TCGTGCGCAAGCTTGGCGTGCCGTTCCAACCCGAATTGGCTTTCGGCGCCATCGGTGAGGACGGCGTGCGGGTGCTCAAC
GACGACGTCGTCCGCGGGACACACCTCGATGCTGCCGCCATGGACGCGGTCGAACGCAAGCAGCTGATCGAGCTACAACG
CCGCGCGGAACGCTTCCGCCGCGGGCGTGACCGCATCCCGTTGACCGGGCGGATCGCGGTGATCGTCGATGACGGCATCG
CCACCGGAGCGACGGCCAAGGCGGCGTGCCAGGTCGCCCGGGCGCACGGTGCGGACAAGGTGGTGCTGGCGGTCCCGATC
GGCCCAGACGACATCGTGGCGAGATTCGCCGGGTACGCCGATGAGGTGGTGTGTTTGGCGACGCCGGCGTTGTTCTTCGC
CGTCGGGCAGGGTTACCGCAACTTCACCCAGACCTCCGACGACGAGGTGGTGGCGTTTCTGGATCGTGCTCACCGCGACT
TCGCCGAGGCAGGTGCGATCGATGCCGCCGCTGACCCACCGCTTCGCGATGAGGAGGTCCAGGTCGTTGCCGGTCCAGTA
CCGGTGGCAGGGCACCTGACTGTCCCCGAAAAACCCAGGGGAATTGTGGTTTTCGCACATGGCAGTGGCAGCAGCCGGCA
CAGTATCCGCAATCGGTACGTTGCAGAGGTCTTGACCGGGGCCGGGTTTGCGACGCTGTTATTCGACTTGCTCACGCCCG
AAGAAGAACGCAACCGCGCCAACGTCTTCGACATTGAGCTGCTCGCTTCCCGACTCATCGACGTGACCGGTTGGTTGGCC
ACCCAGCCCGACACCGCATCGCTGCCGGTCGGCTACTTCGGCGCCAGCACGGGAGCGGGTGCGGCGCTGGTCGCGGCCGC
CGATCCGCGCGTGAACGTGCGGGCGGTGGTGTCCCGCGGCGGCCGGCCCGATCTCGCGGGTGATTCGCTGGGGAGCGTGG
TGGCACCGACGCTGCTGATCGTGGGTGGACGCGACCAGGTGGTCCTCGAGCTGAACCAACGAGCGCAAGCGGTAATACCC
GGGAAATGCCAACTCACCGTGGTCCCCGGCGCCACACACCTATTCGAAGAACCAGGCACGCTGGAACAGGTTGCCAAGCT
GGCGTGCGATTGGTTCATCGACCACTTGTGCGGCCCAGGCCCAAGCGGCTAA

Upstream 100 bases:

>100_bases
CAAGGCGGGATGCGCAATCCGGTCGCTGAGGGACTGTCGTCAGTCGGCCCAGGGACCTAATTCCATATTTGGAGCCATGA
GATGGCGACACACTCGGCAG

Downstream 100 bases:

>100_bases
ACCGCTAGCCGGCCGGGGTGATCCCTGCGATCCCTGCGCGAGCAGACGCAGAATCGCATCAAAATCGCTGATTTTGTGCG
ATTCTGCGTCTGCTCGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLN
DDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPI
GPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPV
PVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLA
TQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIP
GKCQLTVVPGATHLFEEPGTLEQVAKLACDWFIDHLCGPGPSG

Sequences:

>Translated_443_residues
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLN
DDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPI
GPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPV
PVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLA
TQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIP
GKCQLTVVPGATHLFEEPGTLEQVAKLACDWFIDHLCGPGPSG
>Mature_443_residues
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGVPFQPELAFGAIGEDGVRVLN
DDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIPLTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPI
GPDDIVARFAGYADEVVCLATPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPV
PVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRANVFDIELLASRLIDVTGWLA
TQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRGGRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIP
GKCQLTVVPGATHLFEEPGTLEQVAKLACDWFIDHLCGPGPSG

Specific function: Unknown

COG id: COG1926

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the dienelactone hydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y0571_MYCTU (O53768)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   B70933
- RefSeq:   NP_215085.1
- RefSeq:   NP_335006.1
- ProteinModelPortal:   O53768
- EnsemblBacteria:   EBMYCT00000000534
- EnsemblBacteria:   EBMYCT00000070643
- GeneID:   887710
- GeneID:   924989
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0597
- KEGG:   mtu:Rv0571c
- TIGR:   MT0597
- TubercuList:   Rv0571c
- GeneTree:   EBGT00050000015242
- HOGENOM:   HBG310173
- OMA:   VFDIGLL
- ProtClustDB:   CLSK871827
- GO:   GO:0005829
- InterPro:   IPR002925
- InterPro:   IPR000836

Pfam domain/function: PF01738 DLH; PF00156 Pribosyltran

EC number: NA

Molecular weight: Translated: 46656; Mature: 46656

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGV
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
PFQPELAFGAIGEDGVRVLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIP
CCCCCCEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVVCLA
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCHHHH
TPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPV
HHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
PVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRA
CCCCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCC
NVFDIELLASRLIDVTGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRG
CEEHHHHHHHHHHHHHHCEECCCCCCCCCCEECCCCCCCCEEEEEECCCCCEEEEEECCC
GRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGT
CCCCCCCCCHHHHHHCEEEEECCCCEEEEEECCCCCEECCCCEEEEEECCCHHHHCCCCH
LEQVAKLACDWFIDHLCGPGPSG
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLFDDRGDAGRQLAQRLAQLSGKAVVVLGLPRGGVPVAFEVAKSLQAPLDVLVVRKLGV
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
PFQPELAFGAIGEDGVRVLNDDVVRGTHLDAAAMDAVERKQLIELQRRAERFRRGRDRIP
CCCCCCEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTGRIAVIVDDGIATGATAKAACQVARAHGADKVVLAVPIGPDDIVARFAGYADEVVCLA
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCHHHH
TPALFFAVGQGYRNFTQTSDDEVVAFLDRAHRDFAEAGAIDAAADPPLRDEEVQVVAGPV
HHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
PVAGHLTVPEKPRGIVVFAHGSGSSRHSIRNRYVAEVLTGAGFATLLFDLLTPEEERNRA
CCCCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCC
NVFDIELLASRLIDVTGWLATQPDTASLPVGYFGASTGAGAALVAAADPRVNVRAVVSRG
CEEHHHHHHHHHHHHHHCEECCCCCCCCCCEECCCCCCCCEEEEEECCCCCEEEEEECCC
GRPDLAGDSLGSVVAPTLLIVGGRDQVVLELNQRAQAVIPGKCQLTVVPGATHLFEEPGT
CCCCCCCCCHHHHHHCEEEEECCCCEEEEEECCCCCEECCCCEEEEEECCCHHHHCCCCH
LEQVAKLACDWFIDHLCGPGPSG
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036