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The map label for this gene is yggA [C]

Identifier: 148660255

GI number: 148660255

Start: 578974

End: 579579

Strand: Direct

Name: yggA [C]

Synonym: MRA_0495

Alternate gene names: 148660255

Gene position: 578974-579579 (Clockwise)

Preceding gene: 148660254

Following gene: 148660256

Centisome position: 13.1

GC content: 60.73

Gene sequence:

>606_bases
ATGATGACGCTCAAGGTCGCGATCGGCCCGCAAAACGCATTTGTCCTGCGCCAAGGAATTAGGCGAGAATACGTGCTGGT
CATTGTGGCGCTGTGCGGGATCGCTGATGGGGCACTGATTGCCGCGGGCGTTGGCGGCTTCGCTGCGCTGATTCACGCTC
ATCCCAATATGACTTTGGTTGCCCGATTTGGCGGCGCAGCGTTCTTGATTGGCTACGCGCTATTGGCCGCGCGGAACGCG
TGGCGCCCGAGCGGGCTGGTGCCGTCGGAATCGGGGCCGGCTGCGCTGATCGGCGTGGTGCAAATGTGCCTGGTGGTGAC
CTTTCTCAACCCACACGTCTATCTGGACACTGTGGTGTTGATCGGTGCCCTCGCCAATGAGGAATCAGATCTGCGGTGGT
TTTTCGGAGCCGGTGCCTGGGCCGCCAGCGTCGTATGGTTCGCCGTGTTGGGATTTAGCGCGGGCCGGCTACAGCCATTC
TTCGCAACTCCAGCTGCTTGGCGCATTCTTGATGCGCTGGTTGCCGTGACGATGATTGGGGTCGCCGTCGTTGTGCTCGT
CACGTCACCAAGTGTGCCGACGGCCAATGTCGCACTGATCATTTGA

Upstream 100 bases:

>100_bases
AGAAATTCGCGATCACAATTTGCGCGTTCAAGTCATTGGCATGCATGTGATGGTTTAGCGTTCCGCTGTGCCTCTTCAGG
TGTTTGTCGGCTTCGTTGCC

Downstream 100 bases:

>100_bases
CCACCTCGTAGGCCGCCCATGTATCGGCCTTGGTGAACCGGCCGTTACGGTGCCGACCACCTCGGCGGTATGAACGCGCT
GCGCAGCGGACCGAGGAGAA

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLVARFGGAAFLIGYALLAARNA
WRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFGAGAWAASVVWFAVLGFSAGRLQPF
FATPAAWRILDALVAVTMIGVAVVVLVTSPSVPTANVALII

Sequences:

>Translated_201_residues
MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLVARFGGAAFLIGYALLAARNA
WRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFGAGAWAASVVWFAVLGFSAGRLQPF
FATPAAWRILDALVAVTMIGVAVVVLVTSPSVPTANVALII
>Mature_201_residues
MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLVARFGGAAFLIGYALLAARNA
WRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFGAGAWAASVVWFAVLGFSAGRLQPF
FATPAAWRILDALVAVTMIGVAVVVLVTSPSVPTANVALII

Specific function: Unknown

COG id: COG1279

COG function: function code R; Lysine efflux permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LysE/ArgO transporter (TC 2.A.75) family

Homologues:

Organism=Escherichia coli, GI1789290, Length=178, Percent_Identity=38.2022471910112, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y488_MYCTU (P64711)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   C70744
- RefSeq:   NP_215002.1
- RefSeq:   NP_334916.1
- EnsemblBacteria:   EBMYCT00000000844
- EnsemblBacteria:   EBMYCT00000071810
- GeneID:   887171
- GeneID:   923866
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0507
- KEGG:   mtu:Rv0488
- TIGR:   MT0507
- TubercuList:   Rv0488
- GeneTree:   EBGT00050000016872
- HOGENOM:   HBG683136
- OMA:   VRFAIDA
- ProtClustDB:   CLSK790552
- InterPro:   IPR004777
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00948

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 20951; Mature: 20951

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c6e3bc8)-; HASH(0x1c6d4534)-; HASH(0x1c29f570)-; HASH(0x1b5aff68)-; HASH(0x1c6f43f8)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLV
CEEEEEEECCCCHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHCCCCCEEEE
ARFGGAAFLIGYALLAARNAWRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVL
EECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
IGALANEESDLRWFFGAGAWAASVVWFAVLGFSAGRLQPFFATPAAWRILDALVAVTMIG
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VAVVVLVTSPSVPTANVALII
HHHHHEEECCCCCCCCEEEEH
>Mature Secondary Structure
MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLV
CEEEEEEECCCCHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHCCCCCEEEE
ARFGGAAFLIGYALLAARNAWRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVL
EECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
IGALANEESDLRWFFGAGAWAASVVWFAVLGFSAGRLQPFFATPAAWRILDALVAVTMIG
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VAVVVLVTSPSVPTANVALII
HHHHHEEECCCCCCCCEEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036