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The map label for this gene is cutL [H]

Identifier: 148660139

GI number: 148660139

Start: 450767

End: 453166

Strand: Reverse

Name: cutL [H]

Synonym: MRA_0382

Alternate gene names: 148660139

Gene position: 453166-450767 (Counterclockwise)

Preceding gene: 148660140

Following gene: 148660138

Centisome position: 10.25

GC content: 65.88

Gene sequence:

>2400_bases
ATGACAACGATCGAGTCACGCCCTCCGTCGCCGGAAGACCTAGCCGACAACGCTCAGCAGCCGTGCGGGCACGGCCGGAT
GATGCGCAAAGAGGACCCGCGATTCATCCGCGGGCGCGGAACCTACGTCGACGACGTCGCGCTGCCGGGCATGTTGCATC
TGGCCATCCTGCGTTCGCCGTATGCGCATGCCCGCATCGTGCGCATCGATGTGACTGCCGCGCAGGCACATCCGAAAGTC
AAGGCCGTGGTGACCGGCGCCGATCTGGCCGCCAAGGGCCTGGCTTGGATGCCGACACTAGCCAACGACGTACAAGCCGT
GCTGGCCACCGACAAGACGCGCTTCCAGGGCCAAGAGGTGGCGTTCGTGGTTGCCGAGGACCGGTATTCGGCCCGCGATG
CATGCGAGTTGGTCGACGTCGACTACGAACCGCGGGATCCCGTCGTGGATGCCCGCACGGCGCTGGACCCGTCGGCGCCG
GTCATCCGCACCGATCTGGAGGGAAAGAGCGACAATCACATCTTCGACTGGGAGACCGGCGACGCGGCGGCGACCGAGGC
GGTGTTCGCCAAGGCCGACGTCGTTGTCCAGCAGGAGATCGTCTACCCGCGGGTGCACCCGGCGCCGATGGAAACCTGTG
GCGCGGTGGCCGATCTAGATCCGGTCACCGGAAAGCTGACGCTGTGGACCACCAGCCAGGCGCCGCACGCGCATCGCACG
CTATACGCGCTGGTGGCCGGGTTGCCCGAACACAAGATTCGGGTGATCTCGCCCGACATCGGCGGCGGCTTCGGCAACAA
GGTGCCGATCTATCCCGGTTATGTCTGTGCCATTGTCGCGTCGCTGCTGCTGGACAAGCCGGTCAAATGGATGGAGGACC
GCAGCGAGAACCTGACGTCCACCGGATTCGCCCGCGACTACATCATGGTCGGCGAGATTGCCGCCAACCGTGACGGCAAG
ATCCTGGCGATCCGGTCCAATGTGCTGGCCGACCATGGTGCGTTTAACGCCCAGGCCGCGCCGGCGAAGTACCCAGCCGG
GTTCTTCGGGGTGTTCACCGGCAGCTACGACATCGAGGCCGCCTACTGTCACATGACCGCGGTGTATACCAACAAGGCGC
CCGGCGGGGTCGCCTACGCGTGTTCGTTCCGCATCACCGAAGCGGTCTACTTCGTCGAGCGGCTGGTGGACTGCCTGGCC
TTCGAGCTGAAGATGGATCCAGCCGAGCTGCGCTTGCGGAATCTATTGCGGCCCAACCAGTTTCCGTATCAGAGCAAGAC
TGGTTGGGTGTACGACTCGGGCGACTACGAGACCACAATGCGTAAGGCGATGAACATGATCGGCTACGAGGCGTTACGCG
CCGAACAAAAGCAGCGGCGAGCGCGCGGCGAGCTGATGGGCATCGGGATGTCATTTTTCACCGAGGCCGTGGGCGCCGGG
CCGCGCAAGGACATGGACATCCTCGGCCTGGGCATGGCCGACGGCTGCGAGCTGCGCGTGCACCCGACGGGCAAAGCCGT
GCTGCGGCTTTCGGTTCAGACCCAGGGCCAGGGCCACGAGACGACGTTCGCGCAGATCGTCGCCGAGGAGCTGGGGATTG
CGCCCGACGACATCGAGGTGGTGCACGGCGACACCGACCAGACACCGTTCGGGTTGGGCACCTACGGCAGCCGGTCCACA
CCCGTCTCGGGTGGTGCCGCGGCGCTGGTCGCCCGCAAGGTGCGCGACAAGGCCAAGATCATCGCCTCGGGCATGCTCGA
GGTTTCGGTCGCCGACTTACAGTGGGAGAAAGGGAAGTTCCACGTCAAGGGTGACCCGTCGGCCGCGGTGACCATCGCCG
ACATCGCGATGCGCGCGCACGGCGCCGGCGATCTGCCCGAGGGCATCGAGGGCGGGCTGGATGCCGAGGTCTGCTACAAC
CCGTCGAATCTGACCTACCCGTACGGCGCCTACTTCTGTGTGGTCGACATCGACCCGGGCACCGCGGTGGTGAAGGTGCG
GCGCTTTTTGGCCGTCGATGATTGCGGAACCCGGATCAACCCGATGATCATCGAGGGTCAGGTACACGGCGGCATCGTCG
ACGGCATCGGCATGGCGCTGATGGAGATGATTGCCTTCGACGAGGACGGCAACTGTCTGGGCGGATCGTTGATGGACTAC
CTGATCCCGACCGCGCTCGAGGTGCCACACCTAGAGACCGGGCACACCGTGACCCCGTCGCCGCATCACCCGATCGGCGC
CAAGGGCATCGGTGAGTCGGCCACGGTGGGTTCCCCGCCGGCGGTGGTGAACGCGGTGGTGGATGCGTTGGCGCCGTTCG
GGGTTCGGCACGCCGACATGCCGTTGACGCCGTCGCGGGTCTGGGAGGCCATGCAGGGCCGGGCCACACCACCGATCTAG

Upstream 100 bases:

>100_bases
GGGAAGCGATCTCGGGGCAGATCTGCCGGTGCACCGGATACACCACGATCGTGCGCTCCATTCAGTGGGCGGCAGCGCAC
CAGACCGTAAAGGCGCAGTC

Downstream 100 bases:

>100_bases
GGGAGCTCGAGGGCGTCGATGTCCATCAGTGACCGGGCCGCACAGCTGGTGGCCGCGCGGACACCGTTCGTGCGCGCGAC
CGTGGTGCGGGCCCAGCAGC

Product: putative carbon monoxide dehydrogenase large subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 799; Mature: 798

Protein sequence:

>799_residues
MTTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKV
KAVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAP
VIRTDLEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRT
LYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFARDYIMVGEIAANRDGK
ILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLA
FELKMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAG
PRKDMDILGLGMADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGSRST
PVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN
PSNLTYPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDY
LIPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPPI

Sequences:

>Translated_799_residues
MTTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKV
KAVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAP
VIRTDLEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRT
LYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFARDYIMVGEIAANRDGK
ILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLA
FELKMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAG
PRKDMDILGLGMADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGSRST
PVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYN
PSNLTYPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDY
LIPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPPI
>Mature_798_residues
TTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSPYAHARIVRIDVTAAQAHPKVK
AVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEVAFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPV
IRTDLEGKSDNHIFDWETGDAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRTL
YALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTSTGFARDYIMVGEIAANRDGKI
LAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAF
ELKMDPAELRLRNLLRPNQFPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAGP
RKDMDILGLGMADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEVVHGDTDQTPFGLGTYGSRSTP
VSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKFHVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNP
SNLTYPYGAYFCVVDIDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDYL
IPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADMPLTPSRVWEAMQGRATPPI

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=803, Percent_Identity=23.0386052303861, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI91823271, Length=797, Percent_Identity=22.3337515683814, Blast_Score=105, Evalue=2e-22,
Organism=Escherichia coli, GI1789230, Length=778, Percent_Identity=28.9203084832905, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1789246, Length=821, Percent_Identity=26.3093788063337, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1786478, Length=739, Percent_Identity=25.7104194857916, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17540638, Length=793, Percent_Identity=23.3291298865069, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85890; Mature: 85759

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSP
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEECCHHCCHHHHHHHHHCC
YAHARIVRIDVTAAQAHPKVKAVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEV
CCCEEEEEEEEEECCCCCCEEEEEECCCHHHCCCEECCHHHHHHHHHHHCCCHHCCCCEE
AFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLEGKSDNHIFDWETG
EEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCEEEECCCC
DAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRT
CHHHHHHHHHHHHHEEEHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCHHHHH
LYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTS
HHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCC
TGFARDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIEA
CCCCCCEEEEEEEECCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEE
AYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAELRLRNLLRPNQ
EEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAG
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCC
PRKDMDILGLGMADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEV
CCCCCEEEEECCCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
VHGDTDQTPFGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKF
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEE
HVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGAYFCVVDIDPG
EECCCCCCEEEHHHHHHHHCCCCCCCCHHCCCCCCEEEECCCCCCCCCCEEEEEEEECCC
TAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDY
HHHHHHHHHHEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LIPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADM
HHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PLTPSRVWEAMQGRATPPI
CCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTIESRPPSPEDLADNAQQPCGHGRMMRKEDPRFIRGRGTYVDDVALPGMLHLAILRSP
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEECCHHCCHHHHHHHHHCC
YAHARIVRIDVTAAQAHPKVKAVVTGADLAAKGLAWMPTLANDVQAVLATDKTRFQGQEV
CCCEEEEEEEEEECCCCCCEEEEEECCCHHHCCCEECCHHHHHHHHHHHCCCHHCCCCEE
AFVVAEDRYSARDACELVDVDYEPRDPVVDARTALDPSAPVIRTDLEGKSDNHIFDWETG
EEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCEEEECCCC
DAAATEAVFAKADVVVQQEIVYPRVHPAPMETCGAVADLDPVTGKLTLWTTSQAPHAHRT
CHHHHHHHHHHHHHEEEHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCHHHHH
LYALVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVASLLLDKPVKWMEDRSENLTS
HHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCC
TGFARDYIMVGEIAANRDGKILAIRSNVLADHGAFNAQAAPAKYPAGFFGVFTGSYDIEA
CCCCCCEEEEEEEECCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEE
AYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAFELKMDPAELRLRNLLRPNQ
EEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
FPYQSKTGWVYDSGDYETTMRKAMNMIGYEALRAEQKQRRARGELMGIGMSFFTEAVGAG
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCC
PRKDMDILGLGMADGCELRVHPTGKAVLRLSVQTQGQGHETTFAQIVAEELGIAPDDIEV
CCCCCEEEEECCCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
VHGDTDQTPFGLGTYGSRSTPVSGGAAALVARKVRDKAKIIASGMLEVSVADLQWEKGKF
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEE
HVKGDPSAAVTIADIAMRAHGAGDLPEGIEGGLDAEVCYNPSNLTYPYGAYFCVVDIDPG
EECCCCCCEEEHHHHHHHHCCCCCCCCHHCCCCCCEEEECCCCCCCCCCEEEEEEEECCC
TAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEDGNCLGGSLMDY
HHHHHHHHHHEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LIPTALEVPHLETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGVRHADM
HHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PLTPSRVWEAMQGRATPPI
CCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]