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The map label for this gene is dedA [C]

Identifier: 148660130

GI number: 148660130

Start: 443758

End: 444441

Strand: Direct

Name: dedA [C]

Synonym: MRA_0373

Alternate gene names: 148660130

Gene position: 443758-444441 (Clockwise)

Preceding gene: 148660128

Following gene: 148660133

Centisome position: 10.04

GC content: 62.13

Gene sequence:

>684_bases
ATGAGCACCGCCGTGACGGCCATGCCGGACATCCTCGACCCGATGTACTGGTTGGGCGCCAACGGCGTATTCGGTTCCGC
GGTGCTGCCCGGGATTTTGATCATCGTCTTCATCGAGACCGGTCTGCTGTTTCCGCTGCTGCCGGGCGAGTCGCTGTTGT
TCACCGGCGGGCTGTTGTCCGCTAGCCCGGCACCACCGGTCACCATCGGGGTGCTCGCCCCGTGCGTTGCGCTGGTCGCG
GTGCTCGGCGATCAGACCGCATATTTCATCGGGCGACGGATCGGGCCGGCGCTGTTCAAGAAGGAAGACTCCCGGTTCTT
CAAGAAACACTATGTGACCGAGTCCCACGCGTTTTTTGAGAAGTACGGGAAATGGACGATAATTCTGGCTCGATTCGTGC
CGATCGCGCGGACTTTTGTGCCAGTCATTGCCGGGGTGTCCTACATGCGGTATCCGGTGTTCCTCGGGTTCGACATCGTC
GGCGGAGTCGCCTGGGGTGCGGGTGTGACGTTGGCGGGCTACTTTTTGGGCAGTGTCCCGTTCGTGCACATGAACTTTCA
GCTCATCATCCTGGCCATCGTGTTCGTCTCACTGTTGCCCGCACTGGTCTCGGCGGCGCGGGTCTACCGGGCGCGGCGTA
ACGCACCCCAGAGCGACCCCGACCCGTTGGTGTTACCCGAGTGA

Upstream 100 bases:

>100_bases
GGCATGAAACGTTCCTCCTGACGACTCCGATCCACCCAGTATCGCAACACCGCAACCGAGCTTGTCGGCCTGTGCGTGAT
GGCCGGTATGTTGGGACGTC

Downstream 100 bases:

>100_bases
GCTGACCGCTGCGGCGCTGTGGGCGGCTTCCATCAGCATCCAACCCGATAGCTGCACCGACAGATCTCGCTCGGCAATCG
CCGAGCTATGCACCGCTCCT

Product: putative transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSTAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLFPLLPGESLLFTGGLLSASPAPPVTIGVLAPCVALVA
VLGDQTAYFIGRRIGPALFKKEDSRFFKKHYVTESHAFFEKYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIV
GGVAWGAGVTLAGYFLGSVPFVHMNFQLIILAIVFVSLLPALVSAARVYRARRNAPQSDPDPLVLPE

Sequences:

>Translated_227_residues
MSTAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLFPLLPGESLLFTGGLLSASPAPPVTIGVLAPCVALVA
VLGDQTAYFIGRRIGPALFKKEDSRFFKKHYVTESHAFFEKYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIV
GGVAWGAGVTLAGYFLGSVPFVHMNFQLIILAIVFVSLLPALVSAARVYRARRNAPQSDPDPLVLPE
>Mature_226_residues
STAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLFPLLPGESLLFTGGLLSASPAPPVTIGVLAPCVALVAV
LGDQTAYFIGRRIGPALFKKEDSRFFKKHYVTESHAFFEKYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIVG
GVAWGAGVTLAGYFLGSVPFVHMNFQLIILAIVFVSLLPALVSAARVYRARRNAPQSDPDPLVLPE

Specific function: Unknown

COG id: COG0586

COG function: function code S; Uncharacterized membrane-associated protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dedA family

Homologues:

Organism=Escherichia coli, GI1788656, Length=185, Percent_Identity=40, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1789481, Length=150, Percent_Identity=34, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789384, Length=168, Percent_Identity=30.3571428571429, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y364_MYCTU (O06314)

Other databases:

- EMBL:   BX842573
- EMBL:   AE000516
- PIR:   E70576
- RefSeq:   NP_214878.1
- RefSeq:   NP_334787.1
- ProteinModelPortal:   O06314
- EnsemblBacteria:   EBMYCT00000003413
- EnsemblBacteria:   EBMYCT00000071159
- GeneID:   886473
- GeneID:   923570
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0380
- KEGG:   mtu:Rv0364
- TIGR:   MT0380
- TubercuList:   Rv0364
- GeneTree:   EBGT00050000017505
- HOGENOM:   HBG657460
- OMA:   YARHGGK
- ProtClustDB:   CLSK790464
- InterPro:   IPR015414

Pfam domain/function: PF09335 SNARE_assoc

EC number: NA

Molecular weight: Translated: 24489; Mature: 24358

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c182f64)-; HASH(0xd0e9940)-; HASH(0x1bfd8bcc)-; HASH(0x1bd96ac8)-; HASH(0x1bf69c14)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLFPLLPGESLLFTGGLLS
CCCCHHHCHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCCC
ASPAPPVTIGVLAPCVALVAVLGDQTAYFIGRRIGPALFKKEDSRFFKKHYVTESHAFFE
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIVGGVAWGAGVTLAGYFLGSVP
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FVHMNFQLIILAIVFVSLLPALVSAARVYRARRNAPQSDPDPLVLPE
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
>Mature Secondary Structure 
STAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLFPLLPGESLLFTGGLLS
CCCHHHCHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCCC
ASPAPPVTIGVLAPCVALVAVLGDQTAYFIGRRIGPALFKKEDSRFFKKHYVTESHAFFE
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIVGGVAWGAGVTLAGYFLGSVP
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FVHMNFQLIILAIVFVSLLPALVSAARVYRARRNAPQSDPDPLVLPE
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036