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The map label for this gene is fadE6 [H]

Identifier: 148660036

GI number: 148660036

Start: 327628

End: 329823

Strand: Reverse

Name: fadE6 [H]

Synonym: MRA_0279

Alternate gene names: 148660036

Gene position: 329823-327628 (Counterclockwise)

Preceding gene: 148660037

Following gene: 148660034

Centisome position: 7.46

GC content: 66.71

Gene sequence:

>2196_bases
ATGTCGATCGCTATTACTCCTGAGCATTATGAGCTGGCCGATTCGGTGCGTTCCCTGGTGGCGCGGGTAGCGCCGTCCGA
GGTGCTGCACGCGGCGCTAGAATCACCGGTCGAAAACCCGCCGCCTTACTGGCAGGCCGCGGCCGAACAAGGCTTGCAGG
GTGTGCATCTGGCCGAGTCGGTCGGCGGCCAGGGTTTCGGCATCCTCGAGCTAGCGGTGGTGCTTGCCGAGTTCGGCTAC
GGCGCCGTGCCCGGGCCGTTCGTGCCGTCGGCGATCGCCAGCGCGCTGATCGCAGCCCATGATCCGCAAGCCAAAGTCCT
CGCCGAACTGGCAACCGGTGCGGCCATCGCCGCCTACGCGCTAGATTCCGGGCTGACCGCCACCCGCCATGGCGACGTGC
TGGTGATCCGGGGCGAAGTCCGCGCGGTTCCGGCCGCGGCGCAAGCCTCCGTTCTGGTGCTACCGGTGGCCATCGAAAGC
CGTGACGAGTGGGTTGTACTGCGCAACGATCAGCTCGAGATCGAAGCGGTCAAGAGCCTGGATCCGTTGCGGCCCATCGC
GCATGTTCGGGCCAACGCGGTCGACGTCAGCGACGACGCCCTGCTGAGCAACCTCACGATGACGACCGCTCACGCGCTGA
TGTCCACCCTGCTGTCCGCTGAAGCCGTTGGCGTCGCGCGGTGGGCGACCGACACCGCGTCGGCATATGCCAAGATCCGC
GAACAATTCGGCCGGCCGATCGGGCAATTCCAGGCGATCAAGCACAAGTGCGCCGAGATGATCGCTGACACCGAGCGGGC
CACCGCCGCGGTGTGGGACGCGGCGCGAGCCTTAGACGACGCGGGCGAATCTAGCTCCGACGTCGAATTCGCGGCGGCGG
TGGCGGCGACGCTGGCACCGGCGACCGCTCAGCGCTGCACGCAGGACTGCATTCAGGTGCACGGCGGCATCGGCTTCACC
TGGGAGCATGACACGAACGTCTACTACCGCCGGGCGTTGATGCTGGCCGCGTGCTTTGGCCGCGGCTCGGAGTATCCGCA
GCGGGTGGTGGACACCGCGACGACTGCCGGTATGCGTCCGGTAGACATCGACCTGGACCCCTCTACCGAGAAGCTGCGGG
CCCAGATCCGGGCCGAAGTCGCCGCGCTGAAGGCGATGCCGCGAGAGCCGCGCACTGTCGCGATCGCCGAAGGTGGGTGG
GTGCTGCCATATCTGCCCAAGCCGTGGGGTCGGGCCGCCAGCCCGGTCGAGCAGATCATCATCGCCCAGGAGTTCACCGC
CGGGCGGGTCAAGCGGCCGCAGATTGCCATCGCGACGTGGATCGTGCCGTCGATCGTCGCGTTCGGAACCGACAATCAGA
AGCAGCGCCTCCTGCCGCCAACGTTCCGAGGCGACATTTTCTGGTGCCAGCTGTTCTCCGAGCCGGGCGCGGGATCGGAC
CTGGCTAGCCTGGCAACCAAGGCCACCCGGGTCGACGGTGGCTGGCGCATCACTGGTCAGAAGATCTGGACCACCGGCGC
GCAGTACTCCCAATGGGGTGCGCTGCTGGCGCGGACGGACCCGTCGGCGCCCAAGCACAACGGCATCACCTACTTCCTGC
TGGACATGAAAAGCGAAGGCGTACAAGTGAAGCCGCTGCGCGAGCTCACGGGTAAGGAGTTTTTCAACACCGTCTACCTC
GACGACGTGTTCGTCCCCGACGAGTTGGTGCTCGGGGAGGTGAACCGGGGGTGGGAGGTCAGCCGCAACACCCTGACGGC
CGAGCGGGTGTCGATCGGCGGCAGCGATTCGACCTTCCTCCCCACCCTGGGCGAGTTCGTCGACTTCGTTCGCGATTACC
GTTTCGAAGGACAGTTCGACCAGGTCGCGCGACACCGTGCCGGGCAATTGATCGCCGAGGGCCACGCCACCAAGCTGCTC
AACTTGCGCTCCACGCTGTTGACGCTGGCCGGGGGTGACCCGATGGCGCCGGCGGCGATCTCCAAGCTGTTGTCCATGCG
CACCGGCCAGGGTTATGCCGAATTCGCGGTGTCGTCCTTTGGCACCGATGCGGTGATCGGCGACACAGAGCGATTGCCCG
GCAAGTGGGGCGAGTACCTGCTAGCCAGCCGGGCCACCACCATCTACGGGGGCACGTCGGAGGTCCAGCTCAACATCATC
GCCGAGCGGTTGCTGGGCCTACCCCGCGACCCGTAA

Upstream 100 bases:

>100_bases
TTTCGCCGGCCATCCGCTAGCCAACGTTAATAACCGACCCACCGGTTGTTAGCTTGGAAGGTGCTTGGCCGAAACGTCCA
ACAGCATGGGAAGGCGAGCA

Downstream 100 bases:

>100_bases
GTACCCGCGCGAGCAGCTACAGCTTGCGTAGCTCACGTTTGAGGACCTTGCCGGTGGGGTTGCGCGGTAGCTCGTCGAGG
AAGATCACCTCCCGCGGCAC

Product: acyl-CoA dehydrogenase FadE6

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGY
GAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIES
RDEWVVLRNDQLEIEAVKSLDPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIR
EQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFT
WEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGW
VLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSD
LASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYL
DDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLL
NLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNII
AERLLGLPRDP

Sequences:

>Translated_731_residues
MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGY
GAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIES
RDEWVVLRNDQLEIEAVKSLDPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIR
EQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFT
WEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGW
VLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSD
LASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYL
DDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLL
NLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNII
AERLLGLPRDP
>Mature_730_residues
SIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGYG
AVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIESR
DEWVVLRNDQLEIEAVKSLDPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIRE
QFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFTW
EHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGWV
LPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSDL
ASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYLD
DVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLLN
LRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNIIA
ERLLGLPRDP

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=287, Percent_Identity=27.1777003484321, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI4501859, Length=300, Percent_Identity=29.3333333333333, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4557231, Length=152, Percent_Identity=32.8947368421053, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI187960098, Length=152, Percent_Identity=32.8947368421053, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI226958414, Length=373, Percent_Identity=24.3967828418231, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4501857, Length=324, Percent_Identity=25, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI226958412, Length=323, Percent_Identity=24.7678018575851, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4557235, Length=156, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI76496475, Length=156, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI21361497, Length=172, Percent_Identity=28.4883720930233, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081958, Length=353, Percent_Identity=28.0453257790368, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1786223, Length=295, Percent_Identity=24.406779661017, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=295, Percent_Identity=31.5254237288136, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=347, Percent_Identity=27.9538904899135, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=292, Percent_Identity=27.3972602739726, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=347, Percent_Identity=25.9365994236311, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=238, Percent_Identity=27.3109243697479, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=410, Percent_Identity=25.609756097561, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=197, Percent_Identity=30.4568527918782, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=290, Percent_Identity=26.8965517241379, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=345, Percent_Identity=25.5072463768116, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=189, Percent_Identity=26.4550264550265, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646207, Length=297, Percent_Identity=26.9360269360269, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356377, Length=289, Percent_Identity=26.643598615917, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21355753, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666513, Length=300, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24660351, Length=292, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363737, Length=159, Percent_Identity=28.9308176100629, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 78478; Mature: 78347

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAES
CEEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEHHHH
VGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYA
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHH
LDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEWVVLRNDQLEIEAVKSL
HHCCCEEECCCCEEEEECCCEECCCCCCCEEEEEEEEECCCCCEEEEECCCEEEHHHHCC
DPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIR
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCH
ATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRP
HHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
VDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGWVLPYLPKPWGRAASPVEQII
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHH
IAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSD
HHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCH
LASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEG
HHHHHHHHHCCCCCEEEECCEEEECCCCHHHHCCEEEECCCCCCCCCCEEEEEEEECCCC
VQVKPLRELTGKEFFNTVYLDDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFL
EEECHHHHHHHHHHHHEEEECCEECCCHHEEECCCCCCCCCCCCEEHHHEECCCCCCCHH
PTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHEECCCCCCCHHHH
SKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNII
HHHHHHHCCCCHHHHHHHHCCCCCEECCCHHCCCHHHHHHHHHCCEEEECCCCCEEHHHH
AERLLGLPRDP
HHHHHCCCCCC
>Mature Secondary Structure 
SIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAES
EEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEHHHH
VGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYA
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHH
LDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEWVVLRNDQLEIEAVKSL
HHCCCEEECCCCEEEEECCCEECCCCCCCEEEEEEEEECCCCCEEEEECCCEEEHHHHCC
DPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIR
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCH
ATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRP
HHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
VDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGWVLPYLPKPWGRAASPVEQII
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHH
IAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSD
HHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCH
LASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEG
HHHHHHHHHCCCCCEEEECCEEEECCCCHHHHCCEEEECCCCCCCCCCEEEEEEEECCCC
VQVKPLRELTGKEFFNTVYLDDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFL
EEECHHHHHHHHHHHHEEEECCEECCCHHEEECCCCCCCCCCCCEEHHHEECCCCCCCHH
PTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHEECCCCCCCHHHH
SKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNII
HHHHHHHCCCCHHHHHHHHCCCCCEECCCHHCCCHHHHHHHHHCCEEEECCCCCEEHHHH
AERLLGLPRDP
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]