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The map label for this gene is fadE3 [H]

Identifier: 148659979

GI number: 148659979

Start: 259145

End: 260218

Strand: Reverse

Name: fadE3 [H]

Synonym: MRA_0223

Alternate gene names: 148659979

Gene position: 260218-259145 (Counterclockwise)

Preceding gene: 148659981

Following gene: 148659977

Centisome position: 5.89

GC content: 65.08

Gene sequence:

>1074_bases
GTGCGCAACGAGCTCAACGACGACGAAGCGATGCTGGTCGCCACCGTGCGGGCATTCATCGACCGAGACGTGAAGCCAAC
CGTCCGTGAGGTCGAGCATGCCAATAGCTACCCGGAGGCGTGGATCGAGCAGATGAAACACATCGGCATCTACGGCCTGG
CGATCGACGAACAGTACGGCGGGTCGCCGGTGTCGATGCCGTGCTATGTGCAAGTCACCCAGGAGCTGGCACGCGGCTGG
ATGAGCCTGGCCGGCGCGATGGGCGGGCACACCGTCGTCGCCAAATTGCTGACCCTGTTTGGCACCGAGGAACAGCGGCG
GACATATCTGCCCCCGATGGCCAGTGGCGAGCTGCGGGCCACCATGGCGCTAACCGAGCCCGGCGGTGGCTCGGATCTGC
AGAACATGTCGACCACGGCGTTGGCCGACGGCCCTGAAGGCTCTGCCGGGTTGTTGATCAACGGCTGCAAGACGTGGATC
AGCAACGCCCGCCGGTCCGGACTTTTCGCGGTGCTGTGCAAGACCGACCCGAACGCCACACCGCGGCACCAAGGCATGTC
GATCGTGCTCGTCGAACCCGGGCCGGGACTCACGGTGTCGCGGGACTTGCCGAAGTTGGGTTACAAGGGCGTCGAATCCT
GCGAGCTGTCGTTCGACAACCTCCGGGTGCCGGTCTCGGCGATCCTGGGCGGAGCCATGGGTCAAGGCTTTTCGCAGATG
ATGAAGGGACTTGAAACGGGTCGCATCCAAGTGGCCGCGCGGGCGCTGGGCGTGGCGACGGCGGCACTCGAGGACTCGCT
GGCCTACGCTCAGCAACGGGAAAGCTTTGGCCGACCGATCTGGCAGCATCAGGCGGTCGGCAATTACCTGGCCGACATGG
CGACCAAGCTCACAGCGGCCCGTCAGCTGACCCGCTATGCCGCCGAGCGGTACGACAGCGGCCAACGCTGCGATATGGAG
GCCGGGATGGCCAAGTTGTTCGCCTCCGAGGTCGCGATGGAAATCGCCCTAAACGCCGTGCGTATCCACGGCGGCTACGG
CTACTCGACCGAGTACGACGTGGAACGGCGGTGA

Upstream 100 bases:

>100_bases
AAATAGGGCCCGCCGACGCGGATGCCCCCATACCCGCTAGCCACAACGCCACATGCTGGCAGGCTATCGGACAGGGGGTC
AATACGGAGGGCGACAAAAG

Downstream 100 bases:

>100_bases
AGGCACCAACGAGATCCAGCGCAACGTGATAGCCGGACAACTGGTGGCCCGGGGCGGGATATAGCCGGTGTCTGGGTGGA
CAGGTCGGGCCCCCGGCAGC

Product: acyl-CoA dehydrogenase FadE3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGW
MSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDME
AGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERR

Sequences:

>Translated_357_residues
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGW
MSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDME
AGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERR
>Mature_357_residues
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGW
MSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDME
AGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=355, Percent_Identity=36.3380281690141, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI4501859, Length=354, Percent_Identity=33.6158192090396, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI226958412, Length=359, Percent_Identity=31.4763231197772, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI7656849, Length=358, Percent_Identity=33.2402234636872, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI4557231, Length=355, Percent_Identity=31.5492957746479, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI187960098, Length=355, Percent_Identity=31.5492957746479, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI226958414, Length=320, Percent_Identity=32.8125, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI4501857, Length=362, Percent_Identity=32.0441988950276, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=30.4709141274238, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI4557235, Length=353, Percent_Identity=29.7450424929178, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=29.7450424929178, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI7669494, Length=363, Percent_Identity=28.9256198347107, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4503943, Length=363, Percent_Identity=28.9256198347107, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI38505218, Length=366, Percent_Identity=26.5027322404372, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI211971008, Length=271, Percent_Identity=30.9963099630996, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI48976061, Length=271, Percent_Identity=30.9963099630996, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI87081958, Length=364, Percent_Identity=31.5934065934066, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786223, Length=365, Percent_Identity=28.7671232876712, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081702, Length=366, Percent_Identity=24.3169398907104, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=356, Percent_Identity=34.8314606741573, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=358, Percent_Identity=33.7988826815642, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17538396, Length=357, Percent_Identity=32.7731092436975, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=34.5505617977528, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17570075, Length=358, Percent_Identity=33.7988826815642, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17569725, Length=333, Percent_Identity=32.7327327327327, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=36.0424028268551, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=35.4430379746835, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71985184, Length=341, Percent_Identity=28.4457478005865, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17533517, Length=354, Percent_Identity=27.683615819209, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=311, Percent_Identity=27.3311897106109, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=27.7472527472527, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17551932, Length=344, Percent_Identity=27.3255813953488, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=30.5454545454545, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=357, Percent_Identity=27.1708683473389, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=361, Percent_Identity=26.8698060941828, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646207, Length=352, Percent_Identity=35.2272727272727, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24666513, Length=356, Percent_Identity=33.9887640449438, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21356377, Length=355, Percent_Identity=34.6478873239437, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI24660351, Length=354, Percent_Identity=32.2033898305085, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI21355753, Length=351, Percent_Identity=30.4843304843305, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281363737, Length=317, Percent_Identity=28.0757097791798, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920834, Length=357, Percent_Identity=26.890756302521, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 38650; Mature: 38650

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYG
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEECCCC
GSPVSMPCYVQVTQELARGWMSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEE
TMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWISNARRSGLFAVLCKTDPNAT
EEEEECCCCCCCHHHCCHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEECCCCCC
PRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
CCCCCCEEEEECCCCCCEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCHHHH
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQLTRYAAERYDSGQRCDMEAGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYG
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEEECCCC
GSPVSMPCYVQVTQELARGWMSLAGAMGGHTVVAKLLTLFGTEEQRRTYLPPMASGELRA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEE
TMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWISNARRSGLFAVLCKTDPNAT
EEEEECCCCCCCHHHCCHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEEEECCCCCC
PRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAMGQGFSQM
CCCCCCEEEEECCCCCCEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCHHHH
MKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQHQAVGNYLADMATKLTAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQLTRYAAERYDSGQRCDMEAGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]