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The map label for this gene is kstR2 [H]

Identifier: 148659922

GI number: 148659922

Start: 188145

End: 188789

Strand: Direct

Name: kstR2 [H]

Synonym: MRA_0166

Alternate gene names: 148659922

Gene position: 188145-188789 (Clockwise)

Preceding gene: 148659921

Following gene: 148659925

Centisome position: 4.26

GC content: 64.5

Gene sequence:

>645_bases
ATGCCATCCGACACCAGCCCCAACGGGCTAAGCCGCCGTGAGGAGTTGCTGGCTGTTGCCACCAAACTATTCGCGGCGCG
CGGTTATCACGGCACCCGGATGGACGACGTCGCCGATGTGATCGGGCTCAACAAAGCAACGGTCTATCACTACTACGCCA
GCAAGTCGCTGATCCTGTTCGACATTTACCGTCAGGCGGCCGAGGGCACCCTGGCCGCCGTGCACGACGATCCGTCCTGG
ACGGCCCGTGAAGCGCTGTACCAGTACACGGTCCGGCTGCTCACTGCGATCGCGAGCAACCCCGAGCGGGCCGCCGTGTA
CTTCCAGGAGCAGCCCTACATCACCGAGTGGTTCACCAGCGAGCAGGTCGCCGAGGTCCGCGAGAAGGAGCAGCAAGTCT
ACGAGCACGTACACGGCCTGATCGACCGCGGGATTGCCAGCGGCGAGTTCTATGAGTGCGACTCGCATGTGGTGGCGCTG
GGGTACATCGGGATGACGCTGGGCAGCTACCGCTGGCTGCGGCCGAGCGGGCGCCGAACGGCCAAGGAGATCGCGGCGGA
GTTCAGCACGGCACTGCTGCGCGGGCTGATCCGCGACGAATCGATCCGCAACCAGTCTCCGCTTGGAACTCGGAAGGAAA
CGTGA

Upstream 100 bases:

>100_bases
ACAGGTTGTCGCCGCCTTGCCTAAACTGAACAACCAGTTGATTGATACAGCTTCGGCCGGGGCCCATGGGCTCCACCGGC
AGCGACGATAGCGAGTAGCG

Downstream 100 bases:

>100_bases
ACCTCACGCGATCGGTGGAATCAATCTCGCTACGGACCCGAGGGCGCCACTGAGCACCGACAACTCCGTCACACTGGATT
GACCGAAGTTGAACATCAGG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSW
TAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVAL
GYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET

Sequences:

>Translated_214_residues
MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSW
TAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVAL
GYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET
>Mature_213_residues
PSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSWT
AREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALG
YIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24128; Mature: 23997

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHHH
DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCH
EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEHHHHHHHHHCCCEEECCCCHHH
AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILF
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHHH
DIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCH
EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEHHHHHHHHHCCCEEECCCCHHH
AKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA