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The map label for this gene is mtn

Identifier: 148659853

GI number: 148659853

Start: 101042

End: 101809

Strand: Direct

Name: mtn

Synonym: MRA_0095

Alternate gene names: 148659853

Gene position: 101042-101809 (Clockwise)

Preceding gene: 148659852

Following gene: 148659854

Centisome position: 2.29

GC content: 65.1

Gene sequence:

>768_bases
ATGGCGGTGACGGTCGGCGTCATTTGTGCGATCCCGCAAGAGCTGGCGTATCTGCGCGGTGTCCTGGTCGATGCGAAACG
CCAGCAGGTCGCGCAGATCCTCTTCGATAGCGGCCAACTCGACGCGCACCGGGTCGTGTTGGCCGCCGCCGGCATGGGCA
AAGTTAACACGGGCCTGACCGCAACGCTGCTTGCCGATCGATTCGGCTGCCGCACCATCGTTTTCACGGGAGTGGCCGGC
GGGCTGGATCCCGAGCTATGCATCGGTGACATCGTCATCGCCGATCGGGTCGTCCAACACGACTTCGGTCTGCTCACCGA
TGAGCGGCTGCGCCCCTATCAGCCCGGACACATCCCCTTCATCGAACCGACCGAGCGGCTCGGATACCCGGTTGATCCCG
CGGTCATCGATCGGGTCAAACACCGCCTCGACGGGTTCACGCTGGCGCCGCTGTCCACCGCCGCGGGAGGTGGTGGCCGG
CAGCCACGCATCTACTACGGCACCATCCTGACCGGTGACCAATACCTTCACTGCGAGCGCACCCGCAACCGGCTGCACCA
CGAACTCGGCGGTATGGCCGTCGAAATGGAAGGCGGTGCGGTGGCGCAAATCTGCGCGTCCTTCGATATCCCATGGCTGG
TCATTCGCGCGCTCTCCGATCTCGCCGGAGCCGATTCGGGGGTGGACTTCAATCGGTTTGTCGGCGAGGTGGCGGCCAGT
TCGGCCCGCGTTCTGCTGCGCTTGCTGCCGGTGTTGACGGCCTGTTGA

Upstream 100 bases:

>100_bases
GCGCCGAGGGCCGCGACTTTCTCGCTACAATCGCGCGCGGCGCGGGAGAGCCGCTAGCCGCCGGTGACCGGCGATTGGAG
ATTGAGTTGCGACCGAACGG

Downstream 100 bases:

>100_bases
AGACGACTATCCGCCGGTGCGTTCACCGCGTCAGGCGGCTTCGGTGAGGTGAGTAATTTGGTCATTAACTTGGTCATGCC
GCCGCCGATGTTGAGCGGAG

Product: putative 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAG
GLDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGR
QPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAAS
SARVLLRLLPVLTAC

Sequences:

>Translated_255_residues
MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAG
GLDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGR
QPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAAS
SARVLLRLLPVLTAC
>Mature_254_residues
AVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAGG
LDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGRQ
PRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAASS
ARVLLRLLPVLTAC

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH)

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily

Homologues:

Organism=Escherichia coli, GI1786354, Length=251, Percent_Identity=28.6852589641434, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNN_MYCBO (P67657)

Other databases:

- EMBL:   BX248334
- RefSeq:   NP_853762.1
- ProteinModelPortal:   P67657
- SMR:   P67657
- EnsemblBacteria:   EBMYCT00000017998
- GeneID:   1090778
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0094
- GeneTree:   EBGT00050000018357
- HOGENOM:   HBG367723
- OMA:   LEHFPTM
- ProtClustDB:   CLSK790256
- BioCyc:   MBOV233413:MB0094-MONOMER
- BRENDA:   3.2.2.9
- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01704

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =3.2.2.9

Molecular weight: Translated: 27340; Mature: 27209

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLT
CEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCCCCCH
ATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPF
HHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
IEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGRQPRIYYGTILTGDQYLHCER
CCCHHHCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEHHH
TRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAAS
HHHHHHHHHCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SARVLLRLLPVLTAC
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLT
EEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCCCCCH
ATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPF
HHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
IEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGRQPRIYYGTILTGDQYLHCER
CCCHHHCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEHHH
TRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAAS
HHHHHHHHHCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SARVLLRLLPVLTAC
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972