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The map label for this gene is 148659832

Identifier: 148659832

GI number: 148659832

Start: 81982

End: 83031

Strand: Direct

Name: 148659832

Synonym: MRA_0074

Alternate gene names: NA

Gene position: 81982-83031 (Clockwise)

Preceding gene: 148659831

Following gene: 148659833

Centisome position: 1.85

GC content: 61.71

Gene sequence:

>1050_bases
ATGCTCTTCGCGGCCCTGCGTGACATGCAATGGAGAAAGCGCCGCCTGGTCATCACGATCATCAGCACCGGGCTGATCTT
CGGGATGACGCTTGTTTTGACCGGACTCGCGAACGGCTTCCGGGTGGAGGCCCGGCACACCGTCGATTCCATGGGTGTCG
ATGTATTCGTCGTCAGATCCGGCGCTGCTGGACCTTTTCTGGGTTCAATACCGTTTCCCGATGTTGACCTGGCCCGAGTG
GCCGCTGAACCCGGTGTCATGGCCGCGGCCCCGTTGGGCAGCGTGGGGACGATCATGAAAGAAGGCACGTCGACGCGAAA
CGTCACGGTCTTCGGCGCGCCCGAGCACGGACCTGGCATGCCACGGGTCTCAGAGGGTCGGTCACCGTCGAAACCGGACG
AAGTCGCGGCATCGAGCACGATGGGCCGACACCTCGGTGACACTGTCGAGGTCGGCGCGCGCAGATTGCGGGTCGTTGGC
ATTGTGCCGAATTCCACCGCGCTGGCCAAGATCCCCAATGTCTTCCTCACGACCGAGGGCTTACAGAAATTGGCGTACAA
CGGGCAGCCGAATATCACGTCCATCGGGATCATAGGTATGCCCCGACAGCTGCCGGAGGGTTACCAGACTTTCGATCGGG
TGGGCGCTGTCAATGATTTGGTGCGCCCATTGAAGGTCGCAGTGAATTCGATCTCGATCGTGGCTGTTTTGCTGTGGATT
GTGGCGGTGCTGATCGTCGGCTCGGTGGTGTACCTTTCGGCTCTTGAGCGGCTACGTGACTTCGCGGTGTTCAAGGCGAT
TGGCACGCCAACGCGCTCGATTATGGCCGGGCTCGCATTACAGGCGCTGGTCATTGCGTTGCTTGCGGCGGTGGTGGGCG
TCGTCCTGGCGCAGGTGTTGGCACCACTGTTTCCGATGATTGTCGCGGTACCCGTCGGTGCTTACCTGGCGCTACCGGTG
GCCGCGATCGTCATCGGTCTGTTCGCTAGTGTTGCCGGATTGAAGCGCGTGGTGACGGTCGATCCCGCGCAGGCGTTCGG
AGGTCCCTAG

Upstream 100 bases:

>100_bases
CACCACCCCGAACGCCTCTTCGACCACTAGCGGGCCGCGCCCTGACCACAAAACGTCAAGACCAGGCCCCACAAGTGCGC
CACGTTGGTAGCCTCTGGGA

Downstream 100 bases:

>100_bases
CGGTGGGCGATCTCAGCATTCAGAACCTCGTCGTTGAGTACTACAGCGGTGGATACGCGCTTAGGCCGATCAACGGTTTG
AACCTCGACGTGGCAGCCGG

Product: putative glutamine-transport transmembrane protein ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARV
AAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVG
IVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWI
VAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPV
AAIVIGLFASVAGLKRVVTVDPAQAFGGP

Sequences:

>Translated_349_residues
MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARV
AAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVG
IVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWI
VAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPV
AAIVIGLFASVAGLKRVVTVDPAQAFGGP
>Mature_349_residues
MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARV
AAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVG
IVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWI
VAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPV
AAIVIGLFASVAGLKRVVTVDPAQAFGGP

Specific function: Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y072_MYCTU (O53617)

Other databases:

- EMBL:   BX842572
- EMBL:   AE000516
- PIR:   A70849
- RefSeq:   NP_214586.1
- RefSeq:   NP_334488.1
- EnsemblBacteria:   EBMYCT00000002094
- EnsemblBacteria:   EBMYCT00000069466
- GeneID:   886984
- GeneID:   922828
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0078
- KEGG:   mtu:Rv0072
- TIGR:   MT0078
- TubercuList:   Rv0072
- GeneTree:   EBGT00050000016172
- HOGENOM:   HBG569186
- OMA:   DAQEAQF
- ProtClustDB:   CLSK790237
- GO:   GO:0009405
- GO:   GO:0006810
- InterPro:   IPR003838

Pfam domain/function: PF02687 FtsX

EC number: NA

Molecular weight: Translated: 36411; Mature: 36411

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ada4a80)-; HASH(0x1b8eba9c)-; HASH(0x1b04c4b4)-; HASH(0x1b84da8c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRS
CCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCEEEEEEC
GAAGPFLGSIPFPDVDLARVAAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGM
CCCCCCCCCCCCCCCHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCC
PRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVGIVPNSTALAKIPNVFLTTEG
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHEEEEEEECCCCCHHHHCCCCEEEHHH
LQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWI
HHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLFPMIVAVPVGAYLALPVAAIVIGLFASVAGLKRVVTVDPAQAFGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCH
>Mature Secondary Structure
MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRS
CCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCEEEEEEC
GAAGPFLGSIPFPDVDLARVAAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGM
CCCCCCCCCCCCCCCHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCC
PRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVGIVPNSTALAKIPNVFLTTEG
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHEEEEEEECCCCCHHHHCCCCEEEHHH
LQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWI
HHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLFPMIVAVPVGAYLALPVAAIVIGLFASVAGLKRVVTVDPAQAFGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036