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The map label for this gene is yciK [C]

Identifier: 148659828

GI number: 148659828

Start: 76659

End: 77570

Strand: Direct

Name: yciK [C]

Synonym: MRA_0070

Alternate gene names: 148659828

Gene position: 76659-77570 (Clockwise)

Preceding gene: 148659825

Following gene: 148659831

Centisome position: 1.73

GC content: 65.79

Gene sequence:

>912_bases
ATGACCAAATGGACTGCCGCCGACATTCCTGACCAGACCGGCCGGACCGCCGTCATCACGGGGGCCAACACCGGACTTGG
ATTCGAGACCGCCGCAGCGCTTGCCGCCCATGGTGCACACGTGGTGCTGGCTGTGCGCAACCTCGACAAGGGCAAGCAGG
CGGCGGCACGCATCACCGAGGCCACCCCCGGCGCCGAAGTAGAGCTTCAGGAGCTTGACCTGACCTCGCTGGCGTCGGTG
CGCGCCGCCGCGGCACAGCTGAAGTCTGACCACCAGCGCATCGACCTGCTGATCAACAACGCCGGGGTGATGTATACACC
CCGACAGACCACAGCAGACGGCTTCGAGATGCAGTTCGGCACCAACCACTTGGGCCATTTCGCGTTGACCGGCCTGTTGA
TTGATCGACTGCTGCCCGTCGCCGGTTCACGAGTGGTCACCATCAGCAGCGTCGGCCATCGCATCCGTGCCGCAATCCAT
TTCGACGACCTCCAGTGGGAACGCCGGTACAGGCGGGTCGCCGCCTACGGCCAAGCCAAGCTCGCCAACCTGCTGTTCAC
TTATGAACTTCAGCGTCGGTTAGCACCGGGCGGAACCACCATCGCGGTCGCGTCGCACCCGGGAGTGTCCAACACCGAAG
TGGTCCGCAACATGCCACGGCCGCTCGTCGCGGTGGCGGCCATACTGGCGCCGCTGATGCAAGACGCCGAACTGGGGGCC
CTGCCGACATTGCGTGCCGCCACCGATCCCGCGGTGCGCGGCGGCCAGTACTTCGGACCCGATGGCTTCGGTGAAATACG
GGGCTACCCGAAGGTGGTGGCCTCCAGCGCCCAGTCTCACGACGAGCAGCTGCAGCGCCGCCTGTGGGCTGTGTCCGAAG
AGCTCACCGGGGTCGTCTATCCCGTCGGATGA

Upstream 100 bases:

>100_bases
CGTACCTCCGAAAGCCTTGACAAAGCGGGGCGCGCGTTCCGTATAGTTCGGCTAAGCGGAGCGCTCGCCCCGCTTAGTCA
AAGCATAGCGAGGAGCCCTC

Downstream 100 bases:

>100_bases
GCCGGACTCAACGGCAACGGTTGGTCAACACTCGACGATGTTGACTGCGACGTTGATGGCGAGCCCGCCGGCCGAGGTTT
CCTTGTACTTGGTGTGCATG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASV
RAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIH
FDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGA
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG

Sequences:

>Translated_303_residues
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASV
RAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIH
FDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGA
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG
>Mature_302_residues
TKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVR
AAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHF
DDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGAL
PTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=305, Percent_Identity=43.9344262295082, Blast_Score=204, Evalue=7e-53,
Organism=Homo sapiens, GI186928839, Length=287, Percent_Identity=42.8571428571429, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI166795268, Length=285, Percent_Identity=40.7017543859649, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI10190746, Length=304, Percent_Identity=38.8157894736842, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI193804850, Length=299, Percent_Identity=39.1304347826087, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI7706523, Length=297, Percent_Identity=37.3737373737374, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI19923931, Length=262, Percent_Identity=43.5114503816794, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI146231950, Length=296, Percent_Identity=37.5, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI7705421, Length=246, Percent_Identity=27.2357723577236, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI13375997, Length=176, Percent_Identity=32.3863636363636, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI72534732, Length=160, Percent_Identity=32.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=143, Percent_Identity=35.6643356643357, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532791, Length=305, Percent_Identity=34.7540983606557, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI193207620, Length=307, Percent_Identity=34.2019543973941, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17532805, Length=306, Percent_Identity=34.3137254901961, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17558006, Length=295, Percent_Identity=30.8474576271186, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71992402, Length=298, Percent_Identity=32.5503355704698, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17535059, Length=297, Percent_Identity=31.986531986532, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32565532, Length=136, Percent_Identity=41.1764705882353, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505416, Length=309, Percent_Identity=26.537216828479, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI72001364, Length=298, Percent_Identity=29.5302013422819, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533174, Length=285, Percent_Identity=28.7719298245614, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533172, Length=285, Percent_Identity=28.7719298245614, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324820, Length=332, Percent_Identity=29.5180722891566, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573296, Length=295, Percent_Identity=43.728813559322, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI19921754, Length=295, Percent_Identity=42.3728813559322, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI22024069, Length=295, Percent_Identity=41.3559322033898, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161076371, Length=295, Percent_Identity=40.6779661016949, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586328, Length=293, Percent_Identity=39.5904436860068, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI45554248, Length=253, Percent_Identity=43.0830039525692, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24640117, Length=253, Percent_Identity=43.0830039525692, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI20129347, Length=298, Percent_Identity=35.5704697986577, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45553409, Length=250, Percent_Identity=37.2, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24647948, Length=250, Percent_Identity=37.2, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24647946, Length=250, Percent_Identity=37.2, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24647931, Length=300, Percent_Identity=35, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24656154, Length=262, Percent_Identity=35.8778625954198, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI19922628, Length=262, Percent_Identity=35.8778625954198, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21357041, Length=210, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=31.6831683168317, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32399; Mature: 32268

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITE
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHC
ATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFG
CCCCCCEEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCCCCEEEECC
TNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAK
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCEEEEEEEECCHHHHHHHHHHHHHCHHH
LANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
PVG
ECC
>Mature Secondary Structure 
TKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITE
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHC
ATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFG
CCCCCCEEEHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCCCCEEEECC
TNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAK
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCEEEEEEEECCHHHHHHHHHHHHHCHHH
LANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGA
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
LPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVY
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
PVG
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]