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The map label for this gene is pcoA [H]

Identifier: 148652521

GI number: 148652521

Start: 850338

End: 852044

Strand: Direct

Name: pcoA [H]

Synonym: PsycPRwf_0710

Alternate gene names: 148652521

Gene position: 850338-852044 (Clockwise)

Preceding gene: 148652520

Following gene: 148652522

Centisome position: 28.54

GC content: 46.22

Gene sequence:

>1707_bases
ATGAATAAAAAGAACATACTGAACCGCCGACGTTTTTTAACCGGATCCTCTGCTGTCCTTGGTGCCTCCTTGATGCCGAC
TATTGCTAGTAGCGCATTGGGACAATCGAGTCGCTCAGGCAGTCAGGGCGCTACTATTAACAGTGATAAACCCGATCATA
AAGTACCCATACTGACAGGCAAAGAGTTTGATCTTTATGTCAGCAAAAAACCCATCATTGTTGATGGCAAGTCAAGCACG
GCGACGCTCATTAATGACTCATTACCAGCGCCAACGCTAAAAATGCGCGAGGGCGATACGGTAGTGATACGCGTCCATAA
CCAAATGAATGAGTCGACCTCTATTCATTGGCATGGTCTACTAGTACCGTTTGAGATGGATGGCGTGCCCGGCATTAGTT
TTGATGGTATACCAGCAAATAGCACCTTTACGTATAAATTTACGCTGAAACAATCTGGCACTTATTGGTATCACTCGCAC
ACTGGATTCCAAGAACAAACCGGTATGCGCGGGGCCATCGTCATTGAGCCGAAAGGGCGCGAACGTCATCCTATCGAGGA
AGACCATGTCATTTTGCTCAGTGATTGGACGCACCGTGACCCGCACAACTTGGTTAAACTATTAAAGCAACGCGCAGACT
TTGATAATTATCATTTACCAGATTTTAAAAAGCTACTGTCCGATATTGCCGCAACAGATCTAAAAGCTGCTTTTGATAAG
CGCAAAATGTGGAATCAGATGCGCATGATGCCGACAGACTTTACTGATCTGTCTGGTGAAAAAACCTTTACCTATCTGAT
GAATGGTAAAACCACAGCGGCTAACTGGACGCAACTTGTCAAGGCTGGACAGCCTGTCAAACTACGTTTTATTAATGGTT
CAGCGCAGACGATATTTGATGTACGCATCCCCGGCCTAAAAATGAAAGTCGTCGCGACGGATGGGATTGATGTCAGTCCC
GTCGATATCGATGATTTCCGTATTGGGGTGGCCGAGACTTATGATGTCATCGTGACGCCCACTAAAGACGCGCATACCAT
ATTTGCTCAAAACATAGATCGGTCAGGCTATGTTGCGACAACGCTTGCTACCAAAAAAGGTGCTCGTCCTGCGATACCTG
CTATGGACAAAATCGAATGGCTGACGATGGCCGACATGATGGGCGCCATGGGATCGAATGGCTATAACGCTAAACATGCC
AAAACAGAATATGACTTTAAGTCCGATATGCGCGTTGATAGTCCGCGTATGAACCTTGATGACCCTGGTATTAATCTACG
TAACATTGATAGAAAGGTTTTGAATTATAGTCAGTTGCGCTCTGTCGGCGATGAGATAATGGCAGAGCAGCGCAAACCCA
CCAGAGAGATTGAAATACATCTGACGGGAAACATGGAGCGCTATATTTGGGCTCTAGACGGGGTTATGTTCAAAGATGCC
GCACCGGTCAATATTAAGCCCAACGAGCGCGTACGTATTACCTTAGTCAATGACACCATGATGAATCATCCCATGCATTT
GCATGGTATGTGGAGCGATCTGCGGATGCCTTCAGGTGAGTTTCAAGTACGTAAGCATACGATAATGGTACAGCCTGCAC
AAAAGATAAGCTTTGATGTCACCGGAGAAGCTGGCAGATGGGCATGGCATTGCCACTTGCTCTATCACATGGAAGCAGGG
ATGTTTAGAGAAGTTGCCGTTGTTTAA

Upstream 100 bases:

>100_bases
CTGTAGTGTTGGCTTAGATGTGAATAGATTCTGTTAAATATCGAAAATGTTATAACTATAAGCTTAACCACCATCTCTCA
AATTAAATCAGGTTATCATT

Downstream 100 bases:

>100_bases
TAAACCTTCGAATATGAGCCTTATTATGAAAATATATAAAGTAGGTCTACCGTTTATTGGCATGTCATCTTTGATGCTAC
TAATGTCACCTTTAGCAAAC

Product: CopA family copper resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MNKKNILNRRRFLTGSSAVLGASLMPTIASSALGQSSRSGSQGATINSDKPDHKVPILTGKEFDLYVSKKPIIVDGKSST
ATLINDSLPAPTLKMREGDTVVIRVHNQMNESTSIHWHGLLVPFEMDGVPGISFDGIPANSTFTYKFTLKQSGTYWYHSH
TGFQEQTGMRGAIVIEPKGRERHPIEEDHVILLSDWTHRDPHNLVKLLKQRADFDNYHLPDFKKLLSDIAATDLKAAFDK
RKMWNQMRMMPTDFTDLSGEKTFTYLMNGKTTAANWTQLVKAGQPVKLRFINGSAQTIFDVRIPGLKMKVVATDGIDVSP
VDIDDFRIGVAETYDVIVTPTKDAHTIFAQNIDRSGYVATTLATKKGARPAIPAMDKIEWLTMADMMGAMGSNGYNAKHA
KTEYDFKSDMRVDSPRMNLDDPGINLRNIDRKVLNYSQLRSVGDEIMAEQRKPTREIEIHLTGNMERYIWALDGVMFKDA
APVNIKPNERVRITLVNDTMMNHPMHLHGMWSDLRMPSGEFQVRKHTIMVQPAQKISFDVTGEAGRWAWHCHLLYHMEAG
MFREVAVV

Sequences:

>Translated_568_residues
MNKKNILNRRRFLTGSSAVLGASLMPTIASSALGQSSRSGSQGATINSDKPDHKVPILTGKEFDLYVSKKPIIVDGKSST
ATLINDSLPAPTLKMREGDTVVIRVHNQMNESTSIHWHGLLVPFEMDGVPGISFDGIPANSTFTYKFTLKQSGTYWYHSH
TGFQEQTGMRGAIVIEPKGRERHPIEEDHVILLSDWTHRDPHNLVKLLKQRADFDNYHLPDFKKLLSDIAATDLKAAFDK
RKMWNQMRMMPTDFTDLSGEKTFTYLMNGKTTAANWTQLVKAGQPVKLRFINGSAQTIFDVRIPGLKMKVVATDGIDVSP
VDIDDFRIGVAETYDVIVTPTKDAHTIFAQNIDRSGYVATTLATKKGARPAIPAMDKIEWLTMADMMGAMGSNGYNAKHA
KTEYDFKSDMRVDSPRMNLDDPGINLRNIDRKVLNYSQLRSVGDEIMAEQRKPTREIEIHLTGNMERYIWALDGVMFKDA
APVNIKPNERVRITLVNDTMMNHPMHLHGMWSDLRMPSGEFQVRKHTIMVQPAQKISFDVTGEAGRWAWHCHLLYHMEAG
MFREVAVV
>Mature_568_residues
MNKKNILNRRRFLTGSSAVLGASLMPTIASSALGQSSRSGSQGATINSDKPDHKVPILTGKEFDLYVSKKPIIVDGKSST
ATLINDSLPAPTLKMREGDTVVIRVHNQMNESTSIHWHGLLVPFEMDGVPGISFDGIPANSTFTYKFTLKQSGTYWYHSH
TGFQEQTGMRGAIVIEPKGRERHPIEEDHVILLSDWTHRDPHNLVKLLKQRADFDNYHLPDFKKLLSDIAATDLKAAFDK
RKMWNQMRMMPTDFTDLSGEKTFTYLMNGKTTAANWTQLVKAGQPVKLRFINGSAQTIFDVRIPGLKMKVVATDGIDVSP
VDIDDFRIGVAETYDVIVTPTKDAHTIFAQNIDRSGYVATTLATKKGARPAIPAMDKIEWLTMADMMGAMGSNGYNAKHA
KTEYDFKSDMRVDSPRMNLDDPGINLRNIDRKVLNYSQLRSVGDEIMAEQRKPTREIEIHLTGNMERYIWALDGVMFKDA
APVNIKPNERVRITLVNDTMMNHPMHLHGMWSDLRMPSGEFQVRKHTIMVQPAQKISFDVTGEAGRWAWHCHLLYHMEAG
MFREVAVV

Specific function: Required for the copper-inducible expression of copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=180, Percent_Identity=30.5555555555556, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323703, Length=524, Percent_Identity=24.8091603053435, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320714, Length=299, Percent_Identity=23.7458193979933, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321067, Length=141, Percent_Identity=35.4609929078014, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574104, Length=311, Percent_Identity=27.6527331189711, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24650186, Length=326, Percent_Identity=25.4601226993865, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI18859919, Length=304, Percent_Identity=27.3026315789474, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI221329998, Length=578, Percent_Identity=24.7404844290657, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330000, Length=278, Percent_Identity=28.4172661870504, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360167, Length=278, Percent_Identity=28.4172661870504, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24585842, Length=278, Percent_Identity=28.4172661870504, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 63947; Mature: 63947

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKNILNRRRFLTGSSAVLGASLMPTIASSALGQSSRSGSQGATINSDKPDHKVPILTG
CCCHHHHHHHHEECCCCHHHCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEEEEC
KEFDLYVSKKPIIVDGKSSTATLINDSLPAPTLKMREGDTVVIRVHNQMNESTSIHWHGL
CCEEEEECCCCEEEECCCCCEEEEECCCCCCEEEECCCCEEEEEEECCCCCCCEEEEEEE
LVPFEMDGVPGISFDGIPANSTFTYKFTLKQSGTYWYHSHTGFQEQTGMRGAIVIEPKGR
EEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCHHHCCCCEEEEECCCCC
ERHPIEEDHVILLSDWTHRDPHNLVKLLKQRADFDNYHLPDFKKLLSDIAATDLKAAFDK
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RKMWNQMRMMPTDFTDLSGEKTFTYLMNGKTTAANWTQLVKAGQPVKLRFINGSAQTIFD
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEE
VRIPGLKMKVVATDGIDVSPVDIDDFRIGVAETYDVIVTPTKDAHTIFAQNIDRSGYVAT
EECCCEEEEEEEECCCCCCCCCCCCEEEEEECEEEEEEECCCCCEEEEEECCCCCCEEEE
TLATKKGARPAIPAMDKIEWLTMADMMGAMGSNGYNAKHAKTEYDFKSDMRVDSPRMNLD
EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
DPGINLRNIDRKVLNYSQLRSVGDEIMAEQRKPTREIEIHLTGNMERYIWALDGVMFKDA
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCEEECCC
APVNIKPNERVRITLVNDTMMNHPMHLHGMWSDLRMPSGEFQVRKHTIMVQPAQKISFDV
CCCCCCCCCEEEEEEECCHHHCCCEEEEECHHHHCCCCCCEEEEEEEEEEECHHHCEEEE
TGEAGRWAWHCHLLYHMEAGMFREVAVV
CCCCCCEEEEEEEEEEECCCCCEEEECC
>Mature Secondary Structure
MNKKNILNRRRFLTGSSAVLGASLMPTIASSALGQSSRSGSQGATINSDKPDHKVPILTG
CCCHHHHHHHHEECCCCHHHCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEEEEC
KEFDLYVSKKPIIVDGKSSTATLINDSLPAPTLKMREGDTVVIRVHNQMNESTSIHWHGL
CCEEEEECCCCEEEECCCCCEEEEECCCCCCEEEECCCCEEEEEEECCCCCCCEEEEEEE
LVPFEMDGVPGISFDGIPANSTFTYKFTLKQSGTYWYHSHTGFQEQTGMRGAIVIEPKGR
EEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCHHHCCCCEEEEECCCCC
ERHPIEEDHVILLSDWTHRDPHNLVKLLKQRADFDNYHLPDFKKLLSDIAATDLKAAFDK
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RKMWNQMRMMPTDFTDLSGEKTFTYLMNGKTTAANWTQLVKAGQPVKLRFINGSAQTIFD
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEE
VRIPGLKMKVVATDGIDVSPVDIDDFRIGVAETYDVIVTPTKDAHTIFAQNIDRSGYVAT
EECCCEEEEEEEECCCCCCCCCCCCEEEEEECEEEEEEECCCCCEEEEEECCCCCCEEEE
TLATKKGARPAIPAMDKIEWLTMADMMGAMGSNGYNAKHAKTEYDFKSDMRVDSPRMNLD
EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
DPGINLRNIDRKVLNYSQLRSVGDEIMAEQRKPTREIEIHLTGNMERYIWALDGVMFKDA
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCEEECCC
APVNIKPNERVRITLVNDTMMNHPMHLHGMWSDLRMPSGEFQVRKHTIMVQPAQKISFDV
CCCCCCCCCEEEEEEECCHHHCCCEEEEECHHHHCCCCCCEEEEEEEEEEECHHHCEEEE
TGEAGRWAWHCHLLYHMEAGMFREVAVV
CCCCCCEEEEEEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]