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The map label for this gene is apbE [H]

Identifier: 148652507

GI number: 148652507

Start: 837930

End: 839012

Strand: Direct

Name: apbE [H]

Synonym: PsycPRwf_0696

Alternate gene names: 148652507

Gene position: 837930-839012 (Clockwise)

Preceding gene: 148652506

Following gene: 148652508

Centisome position: 28.13

GC content: 47.37

Gene sequence:

>1083_bases
ATGCACACAAATATGTCCAATCAAACAACACCGCAACTGGCAACGATTAAACTGTTTGCCATGGGTTGTCACATTCAAAT
TAGCTTAAATACCACAAGACTGAGCGCGCAACCTTCACAAATGAGAATAGACCAACAAGTCGCTTTTTTGACAAACGATA
TTCAGCAGCGCTTAGCTGACTGGGAACATATCTTCAGTCGTTTTGATGACAGCAGTGAGCTTATGAGACTGAATAACCGT
GGCGACCAATGGTCTGAGGTGAGTTCAGAATTATTTGAGGTGTTGCAGCGTGCCATTCACTTTGTCTCAAAGACTCAAGG
CTTAGTAACACCAACGTTATTGCACCCTCTATGGGACGCAGGCTATAAGCATTCATTTGAGACCTTGCCCAAAATGTCTG
TGCCATCATTACCTGTTACTAGCGTAAGCACCCCTACAAACGTGCAAGACACGACAAGTGCTAACCATGCCAATCAGCAG
ATAGAAGGTATTCAGCTTCGCCAGTTAGCTGACAGACAACATCAAGTATATCTGCCAGCTGGCATGGCACTGGATTTGAA
TGGATATGTCAAAGGGTGGTGCGCCATGCAGTTGGCGGAAAATATTAGCCGAGTTCATGACTGGCATATTCCCTGCTTAG
TCGATATGGGTGGGGATATCGCGATTGGTGTTCCAAAAAACCCAACAGATAAACCGGTGTCTTGGGGAGTGGCTGTTGCC
AAGCCGTATTTTGCCAATAGTGAGCACGTTCACAATGATGAAGATGTGGCGATCCTCAAGCTCAGCTCTGGGGCTGTCGC
CACATCTGGGCAAGATTATCGTCGCTGGTTGCACGACGGCCGCTGGCAACATCATTTGATCCATCCGCATGACTTGCGTC
CAGTAACAAGTGACGTCCTAACTGCAACGGTACTGGCGAAAGATGCGATGACGGCGGAGGTATACGCCAAATACTGCGTG
CTTCTTGGTGTTAAAGCAGCCGTGGCGTGGCTCAACAAACACCATATTGCGGCGTTGTTAATAGATAGGGATAACAAAGT
GATGGTGACTTCTGCCATGCGTCCAAACCTGCTTGCTAGTTAA

Upstream 100 bases:

>100_bases
GTTGAGGTAATAAGGGTTGTCGCTCGTACGCGATCTTCTCAATAAATAAGAAAAACCACAGATTATTTAGTTTGAATATT
TAGTCAAGGGAGGGCTTTGA

Downstream 100 bases:

>100_bases
TTTATCACGCGACATGCGCTAGATATCAATACATTAAGTAAAGCCATTCATAGGAGCATAGTCATGCATACAGACCATCC
TACCAGCAGTCATACTGCTT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MHTNMSNQTTPQLATIKLFAMGCHIQISLNTTRLSAQPSQMRIDQQVAFLTNDIQQRLADWEHIFSRFDDSSELMRLNNR
GDQWSEVSSELFEVLQRAIHFVSKTQGLVTPTLLHPLWDAGYKHSFETLPKMSVPSLPVTSVSTPTNVQDTTSANHANQQ
IEGIQLRQLADRQHQVYLPAGMALDLNGYVKGWCAMQLAENISRVHDWHIPCLVDMGGDIAIGVPKNPTDKPVSWGVAVA
KPYFANSEHVHNDEDVAILKLSSGAVATSGQDYRRWLHDGRWQHHLIHPHDLRPVTSDVLTATVLAKDAMTAEVYAKYCV
LLGVKAAVAWLNKHHIAALLIDRDNKVMVTSAMRPNLLAS

Sequences:

>Translated_360_residues
MHTNMSNQTTPQLATIKLFAMGCHIQISLNTTRLSAQPSQMRIDQQVAFLTNDIQQRLADWEHIFSRFDDSSELMRLNNR
GDQWSEVSSELFEVLQRAIHFVSKTQGLVTPTLLHPLWDAGYKHSFETLPKMSVPSLPVTSVSTPTNVQDTTSANHANQQ
IEGIQLRQLADRQHQVYLPAGMALDLNGYVKGWCAMQLAENISRVHDWHIPCLVDMGGDIAIGVPKNPTDKPVSWGVAVA
KPYFANSEHVHNDEDVAILKLSSGAVATSGQDYRRWLHDGRWQHHLIHPHDLRPVTSDVLTATVLAKDAMTAEVYAKYCV
LLGVKAAVAWLNKHHIAALLIDRDNKVMVTSAMRPNLLAS
>Mature_360_residues
MHTNMSNQTTPQLATIKLFAMGCHIQISLNTTRLSAQPSQMRIDQQVAFLTNDIQQRLADWEHIFSRFDDSSELMRLNNR
GDQWSEVSSELFEVLQRAIHFVSKTQGLVTPTLLHPLWDAGYKHSFETLPKMSVPSLPVTSVSTPTNVQDTTSANHANQQ
IEGIQLRQLADRQHQVYLPAGMALDLNGYVKGWCAMQLAENISRVHDWHIPCLVDMGGDIAIGVPKNPTDKPVSWGVAVA
KPYFANSEHVHNDEDVAILKLSSGAVATSGQDYRRWLHDGRWQHHLIHPHDLRPVTSDVLTATVLAKDAMTAEVYAKYCV
LLGVKAAVAWLNKHHIAALLIDRDNKVMVTSAMRPNLLAS

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=316, Percent_Identity=24.0506329113924, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 40210; Mature: 40210

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTNMSNQTTPQLATIKLFAMGCHIQISLNTTRLSAQPSQMRIDQQVAFLTNDIQQRLAD
CCCCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
WEHIFSRFDDSSELMRLNNRGDQWSEVSSELFEVLQRAIHFVSKTQGLVTPTLLHPLWDA
HHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GYKHSFETLPKMSVPSLPVTSVSTPTNVQDTTSANHANQQIEGIQLRQLADRQHQVYLPA
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCCCEEEECC
GMALDLNGYVKGWCAMQLAENISRVHDWHIPCLVDMGGDIAIGVPKNPTDKPVSWGVAVA
CCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEEC
KPYFANSEHVHNDEDVAILKLSSGAVATSGQDYRRWLHDGRWQHHLIHPHDLRPVTSDVL
CCCCCCCCCCCCCCCEEEEEECCCCEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
TATVLAKDAMTAEVYAKYCVLLGVKAAVAWLNKHHIAALLIDRDNKVMVTSAMRPNLLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MHTNMSNQTTPQLATIKLFAMGCHIQISLNTTRLSAQPSQMRIDQQVAFLTNDIQQRLAD
CCCCCCCCCCCCCEEEEEEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
WEHIFSRFDDSSELMRLNNRGDQWSEVSSELFEVLQRAIHFVSKTQGLVTPTLLHPLWDA
HHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GYKHSFETLPKMSVPSLPVTSVSTPTNVQDTTSANHANQQIEGIQLRQLADRQHQVYLPA
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCCCEEEECC
GMALDLNGYVKGWCAMQLAENISRVHDWHIPCLVDMGGDIAIGVPKNPTDKPVSWGVAVA
CCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEEC
KPYFANSEHVHNDEDVAILKLSSGAVATSGQDYRRWLHDGRWQHHLIHPHDLRPVTSDVL
CCCCCCCCCCCCCCCEEEEEECCCCEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
TATVLAKDAMTAEVYAKYCVLLGVKAAVAWLNKHHIAALLIDRDNKVMVTSAMRPNLLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]