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The map label for this gene is cmoA

Identifier: 148652102

GI number: 148652102

Start: 344360

End: 345184

Strand: Direct

Name: cmoA

Synonym: PsycPRwf_0290

Alternate gene names: 148652102

Gene position: 344360-345184 (Clockwise)

Preceding gene: 148652097

Following gene: 148652103

Centisome position: 11.56

GC content: 47.76

Gene sequence:

>825_bases
ATGTCTAATACAACAGATGCCGATGCTAAGCACCCTCAGTCCAATATCCTTGTTGAAGAAACTGTGGTGTATGACAATGT
GTTCACCACACCGTTAGACAAGGCCGCGCGCTTTTCATTTGATGAGCAAGTGGTGGCCTGTTTTCCTGACATGATTCGCC
GCAGTGTGCCAGGGTACGGGCAAATGCTGGCAATGTTGCCGATTTTTGCCAAGCGTCATTGCCAGGCTGGCCAAGTAAAT
GCTGAGGGCAAACGGGTCAGCCGAGTCTATGACCTTGGGTGCTCGCTGGGCGGGGCCACCATGGCGCTGCTGAATGAAAA
AGGCGGCTTTGGCAAAGAAGAGCTACAAATTAAAGCGGTAGACATCTCGCCGGCAATGACTCAAAAAGCTGAGGTATTGC
TGCAACAGAACTATCCAGAGCACGATATCGAAGTCATTACGGCTGATATTCGCGGATTTGAGCTTGAGCCTTGCGATATG
GTGATATTAAACCTAACCTTGCAGTTCTTACCGCCTGCTGACCGCACCCAAGTACTGCAAAGCATTTATAACGCCTTAAA
TGACGGTGGTATCTTGGTATTGACTGAAAAGACCCACACCGGCGATGAGCAAGATGATGCGTGGTTGGTTGAGCGCTATT
ATGACTTCAAGCGTGCCAATGGGTATAGCGAGCTTGAGATTAGCGGCAAACGTAATGCGTTAGAAAATGTGCTAATTACC
GACACTTTAGATCAGCATCATCAGCGTCTAGCAGAAGTAGGCTTTAATCGTAGTTTGACCTGGTTTCAGTTTTTAAACTT
TGCGTCTATGGTGGCATTTAAATAG

Upstream 100 bases:

>100_bases
AACGAGCTCGGTCTTAATTCTAACAAAATACAATCAGCCGATAAGTTAAAAACAGTAATGTTATAATACAGTGTGTTCAA
AATTGAATAAGAGACTTGAT

Downstream 100 bases:

>100_bases
CCCAAATTTTAAATAAGGCCGCTTGTAAACAGGATGATGGGTGTTCTCTGATCCTCTCAATAAATTGTATTCACATAACG
AATCCTCTATGACAAACCAC

Product: putative methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSNTTDADAKHPQSNILVEETVVYDNVFTTPLDKAARFSFDEQVVACFPDMIRRSVPGYGQMLAMLPIFAKRHCQAGQVN
AEGKRVSRVYDLGCSLGGATMALLNEKGGFGKEELQIKAVDISPAMTQKAEVLLQQNYPEHDIEVITADIRGFELEPCDM
VILNLTLQFLPPADRTQVLQSIYNALNDGGILVLTEKTHTGDEQDDAWLVERYYDFKRANGYSELEISGKRNALENVLIT
DTLDQHHQRLAEVGFNRSLTWFQFLNFASMVAFK

Sequences:

>Translated_274_residues
MSNTTDADAKHPQSNILVEETVVYDNVFTTPLDKAARFSFDEQVVACFPDMIRRSVPGYGQMLAMLPIFAKRHCQAGQVN
AEGKRVSRVYDLGCSLGGATMALLNEKGGFGKEELQIKAVDISPAMTQKAEVLLQQNYPEHDIEVITADIRGFELEPCDM
VILNLTLQFLPPADRTQVLQSIYNALNDGGILVLTEKTHTGDEQDDAWLVERYYDFKRANGYSELEISGKRNALENVLIT
DTLDQHHQRLAEVGFNRSLTWFQFLNFASMVAFK
>Mature_273_residues
SNTTDADAKHPQSNILVEETVVYDNVFTTPLDKAARFSFDEQVVACFPDMIRRSVPGYGQMLAMLPIFAKRHCQAGQVNA
EGKRVSRVYDLGCSLGGATMALLNEKGGFGKEELQIKAVDISPAMTQKAEVLLQQNYPEHDIEVITADIRGFELEPCDMV
ILNLTLQFLPPADRTQVLQSIYNALNDGGILVLTEKTHTGDEQDDAWLVERYYDFKRANGYSELEISGKRNALENVLITD
TLDQHHQRLAEVGFNRSLTWFQFLNFASMVAFK

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=250, Percent_Identity=43.6, Blast_Score=213, Evalue=8e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_PSYWF (A5WC54)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279195.1
- ProteinModelPortal:   A5WC54
- SMR:   A5WC54
- STRING:   A5WC54
- GeneID:   5206013
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0290
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK839536
- BioCyc:   PSP56811:PSYCPRWF_0290-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013217
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08242 Methyltransf_12

EC number: NA

Molecular weight: Translated: 30758; Mature: 30627

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: BINDING 59-59 BINDING 121-121 BINDING 164-164 BINDING 231-231

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTTDADAKHPQSNILVEETVVYDNVFTTPLDKAARFSFDEQVVACFPDMIRRSVPGYG
CCCCCCCCCCCCCCCEEEEHEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHH
QMLAMLPIFAKRHCQAGQVNAEGKRVSRVYDLGCSLGGATMALLNEKGGFGKEELQIKAV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHEEEEECCCCCCCCCEEEEEE
DISPAMTQKAEVLLQQNYPEHDIEVITADIRGFELEPCDMVILNLTLQFLPPADRTQVLQ
ECCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHEEEEEEHHEECCCCCHHHHHH
SIYNALNDGGILVLTEKTHTGDEQDDAWLVERYYDFKRANGYSELEISGKRNALENVLIT
HHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHEEEE
DTLDQHHQRLAEVGFNRSLTWFQFLNFASMVAFK
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNTTDADAKHPQSNILVEETVVYDNVFTTPLDKAARFSFDEQVVACFPDMIRRSVPGYG
CCCCCCCCCCCCCCEEEEHEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHH
QMLAMLPIFAKRHCQAGQVNAEGKRVSRVYDLGCSLGGATMALLNEKGGFGKEELQIKAV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHEEEEECCCCCCCCCEEEEEE
DISPAMTQKAEVLLQQNYPEHDIEVITADIRGFELEPCDMVILNLTLQFLPPADRTQVLQ
ECCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHEEEEEEHHEECCCCCHHHHHH
SIYNALNDGGILVLTEKTHTGDEQDDAWLVERYYDFKRANGYSELEISGKRNALENVLIT
HHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHEEEE
DTLDQHHQRLAEVGFNRSLTWFQFLNFASMVAFK
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA