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The map label for this gene is sdhB [H]

Identifier: 148652076

GI number: 148652076

Start: 311177

End: 311887

Strand: Direct

Name: sdhB [H]

Synonym: PsycPRwf_0264

Alternate gene names: 148652076

Gene position: 311177-311887 (Clockwise)

Preceding gene: 148652075

Following gene: 148652078

Centisome position: 10.45

GC content: 45.99

Gene sequence:

>711_bases
ATGAGCCGAGGTACTCGCACCATTGAGATTTACCGCTACGATCCTGATAAGGACGCAGCCCCTTACATGCAAACTTATAC
GATTGAGCTGTTAGACTCAGATCGTATGTTGCTTGACGTTTTATTACGTTTGAAAAAACAAGATGAATCCATCACTTTTA
GACGCTCATGCCGTGAAGGTATTTGTGGCTCTGATGGGGTGAACATCAATGGTAAAAACGGCTTGGCATGTTTGATTAAC
ATGAACACTTTGCCTGAGAAAATTACCATTCGTCCACTACCTGGCCTGCCTGTTGTGCGTGACCTTGTTGTGGATATGAA
CCAGTTTTATGAGCAGTATGAAAAAGTACATCCGTACTTAATCAACGATCAGCCTGCACCGCCTACTGAGCGTCTACAGT
CTCCAGAAGATCGTGAGAAGCTAAACGGTCTGTATGAGTGTATCTTATGTGCGTGCTGTTCAACCAGTTGCCCATCATTC
TGGTGGAACCCTGATAAGTTCTTAGGCCCATCAGCACTATTGAACGCTTATCGCTTCGTAGCAGACAGCCGTGACAGTGA
TACGCAAGCGCGTCTTGCTCGTATGGACGATCCGTTTAGCTTATTCCGTTGCCGTGGTATCATGAACTGTGTGGCCGTAT
GTCCAAAAGGCTTGAACCCAACCCGTGCTATCGGTCATTTACGTAACTTGTTATTAGAGCAGGCCGGTTAA

Upstream 100 bases:

>100_bases
GTTAATTATTTGAATTTAATTTTTTAAATTAGTAAAGCTGTTTTACAGATACTGTGACAGGTTATGCAAAAACAGCTTTA
CGCCGTGTGGAGTTAGCACT

Downstream 100 bases:

>100_bases
TATCTAATTAGCCCGTTTTAATACAGTAATTAATAGCATTAATTAATATTACAGGTTTAAGTTATCGGTTAGCATTACTT
ACGTGAATACGACAGACCTC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSRGTRTIEIYRYDPDKDAAPYMQTYTIELLDSDRMLLDVLLRLKKQDESITFRRSCREGICGSDGVNINGKNGLACLIN
MNTLPEKITIRPLPGLPVVRDLVVDMNQFYEQYEKVHPYLINDQPAPPTERLQSPEDREKLNGLYECILCACCSTSCPSF
WWNPDKFLGPSALLNAYRFVADSRDSDTQARLARMDDPFSLFRCRGIMNCVAVCPKGLNPTRAIGHLRNLLLEQAG

Sequences:

>Translated_236_residues
MSRGTRTIEIYRYDPDKDAAPYMQTYTIELLDSDRMLLDVLLRLKKQDESITFRRSCREGICGSDGVNINGKNGLACLIN
MNTLPEKITIRPLPGLPVVRDLVVDMNQFYEQYEKVHPYLINDQPAPPTERLQSPEDREKLNGLYECILCACCSTSCPSF
WWNPDKFLGPSALLNAYRFVADSRDSDTQARLARMDDPFSLFRCRGIMNCVAVCPKGLNPTRAIGHLRNLLLEQAG
>Mature_235_residues
SRGTRTIEIYRYDPDKDAAPYMQTYTIELLDSDRMLLDVLLRLKKQDESITFRRSCREGICGSDGVNINGKNGLACLINM
NTLPEKITIRPLPGLPVVRDLVVDMNQFYEQYEKVHPYLINDQPAPPTERLQSPEDREKLNGLYECILCACCSTSCPSFW
WNPDKFLGPSALLNAYRFVADSRDSDTQARLARMDDPFSLFRCRGIMNCVAVCPKGLNPTRAIGHLRNLLLEQAG

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=53.2467532467532, Blast_Score=260, Evalue=9e-70,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=66.3793103448276, Blast_Score=327, Evalue=4e-91,
Organism=Escherichia coli, GI1790596, Length=219, Percent_Identity=35.6164383561644, Blast_Score=144, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=51.5151515151515, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=51.7391304347826, Blast_Score=251, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17137106, Length=234, Percent_Identity=53.8461538461538, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=52.5862068965517, Blast_Score=243, Evalue=7e-65,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26815; Mature: 26684

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGTRTIEIYRYDPDKDAAPYMQTYTIELLDSDRMLLDVLLRLKKQDESITFRRSCREG
CCCCCEEEEEEEECCCCCCCCCHHEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCC
ICGSDGVNINGKNGLACLINMNTLPEKITIRPLPGLPVVRDLVVDMNQFYEQYEKVHPYL
CCCCCCCEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEE
INDQPAPPTERLQSPEDREKLNGLYECILCACCSTSCPSFWWNPDKFLGPSALLNAYRFV
ECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHH
ADSRDSDTQARLARMDDPFSLFRCRGIMNCVAVCPKGLNPTRAIGHLRNLLLEQAG
HCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRGTRTIEIYRYDPDKDAAPYMQTYTIELLDSDRMLLDVLLRLKKQDESITFRRSCREG
CCCCEEEEEEEECCCCCCCCCHHEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCC
ICGSDGVNINGKNGLACLINMNTLPEKITIRPLPGLPVVRDLVVDMNQFYEQYEKVHPYL
CCCCCCCEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEE
INDQPAPPTERLQSPEDREKLNGLYECILCACCSTSCPSFWWNPDKFLGPSALLNAYRFV
ECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHH
ADSRDSDTQARLARMDDPFSLFRCRGIMNCVAVCPKGLNPTRAIGHLRNLLLEQAG
HCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]