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The map label for this gene is moaC [H]

Identifier: 148652036

GI number: 148652036

Start: 260928

End: 261494

Strand: Direct

Name: moaC [H]

Synonym: PsycPRwf_0220

Alternate gene names: 148652036

Gene position: 260928-261494 (Clockwise)

Preceding gene: 148652035

Following gene: 148652037

Centisome position: 8.76

GC content: 49.21

Gene sequence:

>567_bases
ATGTCACTATCAAACTCTGAATCAAACTCAGAATTAACTTCTGAACAAAGCACGCCAGATTTAGCAAGCAACTCTGTGCA
AACACACGCCCACAAGCTATCGCACTTAGATGCCGATGGTGATATTCATATGGTGGATGTGGGCCATAAGACAGTGACCA
CGCGTGAAGCGGTAGCGCAAGGTTATGTGGTATTTCCACAAGACATCTATAGCCAGATTAAAGCCGCCGATGGCATGACC
AAGAAGGGCAGCATCACTCAGACGGCTCATATTGCCGGCATTATGGCCGCCAAGCGTACCCATGATTTAATCCCACTGTG
TCATCCGCTGCCACTTGATAAGGTGGGCTTAAGCTTTAGCTATGAGGATGAGGCATGCGCCATCAAAGTCACCTCCACGG
TGCGCGTCACCCATAAGACTGGGGTGGAGATGGAAGCGTTAACGGCGGTGAGTGTGGCCTGCTTGACCATTTATGATATG
ACCAAGGCGTTATCGCACGACATTATTATCGATGACATGCGCTTGGTGACTAAGACTGGTGGCAAGTCTGACTATCAGAA
GGCTTAG

Upstream 100 bases:

>100_bases
GTTATTCAAAGCCAAGGTTATTCAAAGTTGTTGCAAGCTATAGCCACTTTCTCAATAAAATTTAACCCAGTTAAGCCGAA
CATTTTAGGTCAAAGCTCTT

Downstream 100 bases:

>100_bases
CTAAGCTTAAAATGGGTTGGGTTGGATTGAATTTGCTTTGACGCTGAATAAATGAGGTAGCTGTCACTGGTCGTTATGTT
AAGAGCACCCAACAGGTGTG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSLSNSESNSELTSEQSTPDLASNSVQTHAHKLSHLDADGDIHMVDVGHKTVTTREAVAQGYVVFPQDIYSQIKAADGMT
KKGSITQTAHIAGIMAAKRTHDLIPLCHPLPLDKVGLSFSYEDEACAIKVTSTVRVTHKTGVEMEALTAVSVACLTIYDM
TKALSHDIIIDDMRLVTKTGGKSDYQKA

Sequences:

>Translated_188_residues
MSLSNSESNSELTSEQSTPDLASNSVQTHAHKLSHLDADGDIHMVDVGHKTVTTREAVAQGYVVFPQDIYSQIKAADGMT
KKGSITQTAHIAGIMAAKRTHDLIPLCHPLPLDKVGLSFSYEDEACAIKVTSTVRVTHKTGVEMEALTAVSVACLTIYDM
TKALSHDIIIDDMRLVTKTGGKSDYQKA
>Mature_187_residues
SLSNSESNSELTSEQSTPDLASNSVQTHAHKLSHLDADGDIHMVDVGHKTVTTREAVAQGYVVFPQDIYSQIKAADGMTK
KGSITQTAHIAGIMAAKRTHDLIPLCHPLPLDKVGLSFSYEDEACAIKVTSTVRVTHKTGVEMEALTAVSVACLTIYDMT
KALSHDIIIDDMRLVTKTGGKSDYQKA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=51.2820512820513, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32566331, Length=161, Percent_Identity=43.4782608695652, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574490, Length=156, Percent_Identity=48.7179487179487, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=50, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 20270; Mature: 20139

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSNSESNSELTSEQSTPDLASNSVQTHAHKLSHLDADGDIHMVDVGHKTVTTREAVAQ
CCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHC
GYVVFPQDIYSQIKAADGMTKKGSITQTAHIAGIMAAKRTHDLIPLCHPLPLDKVGLSFS
CEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCEEC
YEDEACAIKVTSTVRVTHKTGVEMEALTAVSVACLTIYDMTKALSHDIIIDDMRLVTKTG
CCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCC
GKSDYQKA
CCCCCCCC
>Mature Secondary Structure 
SLSNSESNSELTSEQSTPDLASNSVQTHAHKLSHLDADGDIHMVDVGHKTVTTREAVAQ
CCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHC
GYVVFPQDIYSQIKAADGMTKKGSITQTAHIAGIMAAKRTHDLIPLCHPLPLDKVGLSFS
CEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCEEC
YEDEACAIKVTSTVRVTHKTGVEMEALTAVSVACLTIYDMTKALSHDIIIDDMRLVTKTG
CCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCC
GKSDYQKA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]