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The map label for this gene is atpA [H]

Identifier: 148652007

GI number: 148652007

Start: 226051

End: 227595

Strand: Direct

Name: atpA [H]

Synonym: PsycPRwf_0191

Alternate gene names: 148652007

Gene position: 226051-227595 (Clockwise)

Preceding gene: 148652006

Following gene: 148652008

Centisome position: 7.59

GC content: 44.6

Gene sequence:

>1545_bases
ATGCAACAATTGAATCCAGCAGAAATCAGTCAACTGATTAAGCAGCGTATTCAAGACCTTGATACGAGTGCAACCGCTAA
AAATGAAGGCACTATTGTCAAAGTATCTGATGGTATTGTTCAGATTCATGGTCTTGAAGATGCGATGTACGGTGAGATGA
TTGAGTTTGAAGGCGATGTCTATGGTATGGCATTGAACCTTGAACAAGACTCCGTCGGTGCGGTTGTTTTGGGTGATTAC
CTAGGTCTTCAAGAAGGTCAAAAAGCTTACTGTACTGGCCGTATTTTAGAAGTACCAGTAGGTCCTGAATTATTAGGCCG
CGTGGTTGACGCCTTAGGTAACCCTATTGATGGTAAAGGCCCAATCAACGCTAAGCTAACTGATAAAGTTGAAAAAATCG
CCCCTGGTGTTATCGCTCGTCAATCTGTTGATGAGCCAGTAATGACCGGTTATAAAGCGGTTGATACCATGATTCCAATC
GGTCGTGGTCAGCGTGAGCTTATCATTGGTGACCGTCAGACCGGTAAAACTGCTATGGCCATCGACGCCATTATTGCTCA
GAAAAACTCTGGCATTAAGTGTGTGTACGTAGCCATCGGTCAAAAACGCTCAACCATCGCAAACGTAGTACGTAAGCTTG
AAGAAACTGGCGCTTTAGCCTACACAACTGTGGTTGTGGCTTCAGCTTCTGAGCCTGCAGCACTTCAGTACATCGCGCCA
TACTCTGGCTGTACTATGGGTGAATACTTCCGTGATCGTGGTGAAGACGCGCTAATCGTTTATGATGACTTATCAAAACA
AGCGGTAGCTTATCGTCAGATTTCACTACTACTACGTCGTCCACCAGGTCGTGAAGCTTATCCAGGTGACGTTTTCTATC
TTCACTCACGCCTATTAGAGCGCGCATCACGCGTAAACGCAGCGTATGTTGAAGAGTTCACTAACGGTGAAGTAAAAGGT
CAGACCGGTTCTTTAACCGCACTACCTATTATTGAAACTCAAGCAGGTGACGTATCTGCATTCGTACCAACCAACGTAAT
TTCTATTACTGATGGTCAGATCTTCTTAGAATCAAGTCTATTTAACTCAGGTATTCGTCCTGCAGTTAACGCCGGTATCT
CTGTATCACGTGTTGGTGGTGCCGCTCAGACTAAGATCATTAAGAAACTATCTGGTGGTATTCGTACTGCATTGGCTCAG
TATCGTGAATTGGCAGCGTTTGCTCAGTTTGCATCTGACCTTGATGATGCGACCAAGCAACAGCTTGATCACGGTGAGCG
TGTTACCGAATTAATGAAGCAGAAGCAGTATCAACCAATGTCAATTGCGGAACAAGCCGCGGTTATCTTCGCCTCGAACG
AAGGTTACTTAAGCGCTATTCCCGTTGAGAAAATTGGTGCATGGGAAGAGGCTTACCTACGTTACATGTATGACGAGCAA
GCTGACTTGATGCAAGAGATTAACGACACTGCAAACTATAATGATGATATTGCGGGCCGATTAAAATCTTCAGTTGAAAC
GTTTTTACAAAACCACACTTTCTAA

Upstream 100 bases:

>100_bases
AAAGTACTTATAACAGTAACTTTTGCCTAATAATAACAGTTACTAAGTACTAATAAACCGGCGAGTAAGCAGGCAATCAC
AAATTAAAGGAAACAAGGCA

Downstream 100 bases:

>100_bases
GTAACAAGGGTGCGATCAGCTTAGCTGGTCGCACTATTTGAAGTGTGACGTTTCAAGATTAATCCTCATTTAAACCCCGC
CGAATTGGAAATGTTATGGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQQLNPAEISQLIKQRIQDLDTSATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGDVYGMALNLEQDSVGAVVLGDY
LGLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKLTDKVEKIAPGVIARQSVDEPVMTGYKAVDTMIPI
GRGQRELIIGDRQTGKTAMAIDAIIAQKNSGIKCVYVAIGQKRSTIANVVRKLEETGALAYTTVVVASASEPAALQYIAP
YSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEEFTNGEVKG
QTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDDATKQQLDHGERVTELMKQKQYQPMSIAEQAAVIFASNEGYLSAIPVEKIGAWEEAYLRYMYDEQ
ADLMQEINDTANYNDDIAGRLKSSVETFLQNHTF

Sequences:

>Translated_514_residues
MQQLNPAEISQLIKQRIQDLDTSATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGDVYGMALNLEQDSVGAVVLGDY
LGLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKLTDKVEKIAPGVIARQSVDEPVMTGYKAVDTMIPI
GRGQRELIIGDRQTGKTAMAIDAIIAQKNSGIKCVYVAIGQKRSTIANVVRKLEETGALAYTTVVVASASEPAALQYIAP
YSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEEFTNGEVKG
QTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDDATKQQLDHGERVTELMKQKQYQPMSIAEQAAVIFASNEGYLSAIPVEKIGAWEEAYLRYMYDEQ
ADLMQEINDTANYNDDIAGRLKSSVETFLQNHTF
>Mature_514_residues
MQQLNPAEISQLIKQRIQDLDTSATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGDVYGMALNLEQDSVGAVVLGDY
LGLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKLTDKVEKIAPGVIARQSVDEPVMTGYKAVDTMIPI
GRGQRELIIGDRQTGKTAMAIDAIIAQKNSGIKCVYVAIGQKRSTIANVVRKLEETGALAYTTVVVASASEPAALQYIAP
YSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEEFTNGEVKG
QTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDDATKQQLDHGERVTELMKQKQYQPMSIAEQAAVIFASNEGYLSAIPVEKIGAWEEAYLRYMYDEQ
ADLMQEINDTANYNDDIAGRLKSSVETFLQNHTF

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=517, Percent_Identity=57.4468085106383, Blast_Score=585, Evalue=1e-167,
Organism=Homo sapiens, GI4757810, Length=517, Percent_Identity=57.4468085106383, Blast_Score=585, Evalue=1e-167,
Organism=Homo sapiens, GI32189394, Length=328, Percent_Identity=26.8292682926829, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913426, Length=381, Percent_Identity=26.246719160105, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913428, Length=318, Percent_Identity=28.9308176100629, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913424, Length=262, Percent_Identity=28.2442748091603, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1790172, Length=512, Percent_Identity=74.8046875, Blast_Score=785, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=388, Percent_Identity=25.7731958762887, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788251, Length=390, Percent_Identity=25.1282051282051, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=511, Percent_Identity=55.3816046966732, Blast_Score=569, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988080, Length=511, Percent_Identity=55.3816046966732, Blast_Score=568, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988074, Length=511, Percent_Identity=51.8590998043053, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=378, Percent_Identity=26.1904761904762, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=314, Percent_Identity=28.9808917197452, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=410, Percent_Identity=23.4146341463415, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=27.1653543307087, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=512, Percent_Identity=54.8828125, Blast_Score=572, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=30.1639344262295, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=331, Percent_Identity=28.0966767371601, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320016, Length=235, Percent_Identity=27.6595744680851, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24658560, Length=511, Percent_Identity=56.1643835616438, Blast_Score=567, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281361666, Length=316, Percent_Identity=28.4810126582279, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=316, Percent_Identity=28.4810126582279, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=316, Percent_Identity=28.4810126582279, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=435, Percent_Identity=24.8275862068966, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28574560, Length=427, Percent_Identity=24.3559718969555, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129479, Length=248, Percent_Identity=28.2258064516129, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55811; Mature: 55811

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLNPAEISQLIKQRIQDLDTSATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGDV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEECCCHHHHCCCEEECCCE
YGMALNLEQDSVGAVVLGDYLGLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKG
EEEEEECCCCCCCEEEEEHHHCCCCCCCEEECCEEEECCCCHHHHHHHHHHHCCCCCCCC
PINAKLTDKVEKIAPGVIARQSVDEPVMTGYKAVDTMIPIGRGQRELIIGDRQTGKTAMA
CCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
IDAIIAQKNSGIKCVYVAIGQKRSTIANVVRKLEETGALAYTTVVVASASEPAALQYIAP
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECC
YSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RASRVNAAYVEEFTNGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSL
HHHHCCHHHHHHHCCCEECCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHH
FNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDDATKQ
HCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLDHGERVTELMKQKQYQPMSIAEQAAVIFASNEGYLSAIPVEKIGAWEEAYLRYMYDEQ
HHHCHHHHHHHHHHHCCCCCHHHCCEEEEEECCCCCEEECCHHHHCCHHHHHHHHHHHHH
ADLMQEINDTANYNDDIAGRLKSSVETFLQNHTF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQLNPAEISQLIKQRIQDLDTSATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGDV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEECCCHHHHCCCEEECCCE
YGMALNLEQDSVGAVVLGDYLGLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKG
EEEEEECCCCCCCEEEEEHHHCCCCCCCEEECCEEEECCCCHHHHHHHHHHHCCCCCCCC
PINAKLTDKVEKIAPGVIARQSVDEPVMTGYKAVDTMIPIGRGQRELIIGDRQTGKTAMA
CCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
IDAIIAQKNSGIKCVYVAIGQKRSTIANVVRKLEETGALAYTTVVVASASEPAALQYIAP
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECC
YSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RASRVNAAYVEEFTNGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSL
HHHHCCHHHHHHHCCCEECCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHH
FNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDDATKQ
HCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLDHGERVTELMKQKQYQPMSIAEQAAVIFASNEGYLSAIPVEKIGAWEEAYLRYMYDEQ
HHHCHHHHHHHHHHHCCCCCHHHCCEEEEEECCCCCEEECCHHHHCCHHHHHHHHHHHHH
ADLMQEINDTANYNDDIAGRLKSSVETFLQNHTF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA