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The map label for this gene is atpB

Identifier: 148652003

GI number: 148652003

Start: 223321

End: 224187

Strand: Direct

Name: atpB

Synonym: PsycPRwf_0187

Alternate gene names: 148652003

Gene position: 223321-224187 (Clockwise)

Preceding gene: 148652002

Following gene: 148652004

Centisome position: 7.5

GC content: 41.06

Gene sequence:

>867_bases
ATGGCAGCTGAAATAACCTCGACTGATTATATTGCTCACCATTTGACCAACTGGACTTATGGCTACTTGCCTGGCGAAGG
CTGGAAAGTAGCTCATACTGCAAAAGAAGCCGGTGAGATGGGCTTTATGGCCATCCATTTGGATTCAATGCTTTGGTCAA
TTGGTCTGGGTATCGTGTTTTGCGCATTATTTTGGTTGGTTGCTAAAAAGGCGACCGCAGGTGTTCCTGGCAAGCTACAA
GCAGCGATCGAGATGATTGTTGAGTTTGTTGACACCAACGTTCGCGATTCTTATAACGGCACATCAAAGTTAATTGCGCC
ATTAGCATTAACAATCTTTGTGTGGATCTTCTTGATGAACTTGATGGACTTAATGCCCATCGACTACATTCCAGTACTTG
CCCAAAAGGTGGGTGCTGCTATGGGCCATGATCCCCATCATGTGTTCTTTAAAATCGTACCAACTACTGATCCGAACATC
ACTTTAGGTATGTCGTTCTCAGTTTTTGCATTGATTATTTATTACAGCATCAAAGAAAAAGGTCTAGGCGGTTTTGTTGG
TGAACTAACCCTTCATCCTTTCAGCGCTAAAAACCCAATTGCAAAGATTATTTTAATCCCAATCAACTTCATCCTAGAAT
TTGTTACTCTAATTGCCAAACCAATTTCACTTGGTCTACGTTTATTCGGTAACATGTACGCAGGTGAGCTGATCTTCGTA
TTGATTGCCTTAATGCCATTTTGGATTCAGTGGGCACTATCAGTACCTTGGGCAATTTTCCATATATTAATTATTACCCT
TCAGGCGTTCGTATTTATGATGTTAACGATAGTTTATCTATCACTAGCGTCACAAACCGAACATTAA

Upstream 100 bases:

>100_bases
GATTTTTTGAGCGCCGAAATTTAATTAGCAAAGAGTTCGAAATTACTATTTTTTGCTAATTAAATTAAAGGTTAACACAC
ACTTATAAGAAGCTAAGATT

Downstream 100 bases:

>100_bases
TTAAAGTTTTTCTTAGGTAAATGAGGATACATCAATGGATCCAGTATTAGGTGGTTACACAGTTATCGCAGTTGCATTAC
TAATTGGTTTTGGTGCTCTA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAAEITSTDYIAHHLTNWTYGYLPGEGWKVAHTAKEAGEMGFMAIHLDSMLWSIGLGIVFCALFWLVAKKATAGVPGKLQ
AAIEMIVEFVDTNVRDSYNGTSKLIAPLALTIFVWIFLMNLMDLMPIDYIPVLAQKVGAAMGHDPHHVFFKIVPTTDPNI
TLGMSFSVFALIIYYSIKEKGLGGFVGELTLHPFSAKNPIAKIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFV
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYLSLASQTEH

Sequences:

>Translated_288_residues
MAAEITSTDYIAHHLTNWTYGYLPGEGWKVAHTAKEAGEMGFMAIHLDSMLWSIGLGIVFCALFWLVAKKATAGVPGKLQ
AAIEMIVEFVDTNVRDSYNGTSKLIAPLALTIFVWIFLMNLMDLMPIDYIPVLAQKVGAAMGHDPHHVFFKIVPTTDPNI
TLGMSFSVFALIIYYSIKEKGLGGFVGELTLHPFSAKNPIAKIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFV
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYLSLASQTEH
>Mature_287_residues
AAEITSTDYIAHHLTNWTYGYLPGEGWKVAHTAKEAGEMGFMAIHLDSMLWSIGLGIVFCALFWLVAKKATAGVPGKLQA
AIEMIVEFVDTNVRDSYNGTSKLIAPLALTIFVWIFLMNLMDLMPIDYIPVLAQKVGAAMGHDPHHVFFKIVPTTDPNIT
LGMSFSVFALIIYYSIKEKGLGGFVGELTLHPFSAKNPIAKIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFVL
IALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYLSLASQTEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=290, Percent_Identity=56.2068965517241, Blast_Score=280, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_PSYWF (A5WBV5)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279096.1
- ProteinModelPortal:   A5WBV5
- SMR:   A5WBV5
- STRING:   A5WBV5
- GeneID:   5204575
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0187
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   LPWWSQF
- ProtClustDB:   PRK05815
- BioCyc:   PSP56811:PSYCPRWF_0187-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 32025; Mature: 31893

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x116de49c)-; HASH(0x125c190c)-; HASH(0x119403ac)-; HASH(0x129b0320)-; HASH(0x12599ec8)-; HASH(0x129b0260)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAEITSTDYIAHHLTNWTYGYLPGEGWKVAHTAKEAGEMGFMAIHLDSMLWSIGLGIVF
CCCCCCCHHHHHHHHCCCEEECCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
CALFWLVAKKATAGVPGKLQAAIEMIVEFVDTNVRDSYNGTSKLIAPLALTIFVWIFLMN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMDLMPIDYIPVLAQKVGAAMGHDPHHVFFKIVPTTDPNITLGMSFSVFALIIYYSIKEK
HHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHC
GLGGFVGELTLHPFSAKNPIAKIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFV
CCCCEEHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYLSLASQTEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
AAEITSTDYIAHHLTNWTYGYLPGEGWKVAHTAKEAGEMGFMAIHLDSMLWSIGLGIVF
CCCCCCHHHHHHHHCCCEEECCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
CALFWLVAKKATAGVPGKLQAAIEMIVEFVDTNVRDSYNGTSKLIAPLALTIFVWIFLMN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMDLMPIDYIPVLAQKVGAAMGHDPHHVFFKIVPTTDPNITLGMSFSVFALIIYYSIKEK
HHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHC
GLGGFVGELTLHPFSAKNPIAKIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFV
CCCCEEHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYLSLASQTEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA