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The map label for this gene is dsbC [H]

Identifier: 148651854

GI number: 148651854

Start: 48862

End: 49977

Strand: Direct

Name: dsbC [H]

Synonym: PsycPRwf_0037

Alternate gene names: 148651854

Gene position: 48862-49977 (Clockwise)

Preceding gene: 148651853

Following gene: 148651856

Centisome position: 1.64

GC content: 47.13

Gene sequence:

>1116_bases
ATGTCGCACTTTTTAAACACACTTAGGCTCATATGCAGTAAATCATTGACCCTATCGCTAGCTATGCCAGTTCTAATATC
GGCCTTGGTCATCATGCCCTCAGCCCATGCTGATTTGTCAGCCTTTAATGAGGCCTATGACAAGCTTGCTGCCAACGATA
GCCGCCCATTAAAAGCGCCAACGCCGCAGCAACAGGATTTTATTAAGCAGATACTGAGTAATGCGGGTATGATGACGCCC
ATTGCCTCTATACAGCCCTCAAAGCTGCCTTCTATGTACCAGATAACCTTGGTACAAAATCCCTCAACTGAGCCGCAGCC
ACCACTGCACATCACCGCTGACGGTGCTTATATTTTGCAAGGCGAATTAAAGCCCAATCCCAGTCCAGTAAAAGTCCCCA
CGCCGCAGCAATTACCGAGCAAAACTTTAAGTGGGATGCCAGTCAGTGATGATTTGCGAGCCTCTATGTTAAAAAACAGC
AGCCTATTAAAGAATATGACGCCCGATGTGGCGCTATATCACACCGCCGTGCCAGGGGTGATTTGGGGCGCAACCTTAAA
GGGGCAGCCTTTTATTACCAATACTGAGGCCACTGTATTTACCAGTGGTGAGATTTCGGTCATTGAAAATGGTCAATTTG
CCGGTCTAGATGCTGATTTTGAACAAAAGAAGAACCTTCATGTCCTCTCTAGTCTTGATGACGACAACCTGGTCATTTAT
CCGGCGACCACTACCGAAAAAGCAGTCATCTATGTCGCCACCGACATCAATTGTCCTTATTGCCGAGTTCTACATCAGGA
TATGGCCAAGCTGAATGCCAAAGGTGTGACGGTTAAAGTCATCGCTTATCCTTACTATGAGCAGTCACCAGAACAAATGC
GTCAGATATGGTGTGCCGCTGACAAAGCAGCCCGCAAACAAGCCTTAGATGAAGCGATGAGTGGCAAGCCTGTGAACAAT
ACCTGTCGCAGTGGTATCGATCATCTAAAGGCAAATCAGGTGAAGGCAGCAGGGCTGGCAGTATTTGCTACGCCTGCTAT
TTATCGAGAAGATGGGGCGGCATTTAACGCACCCTATAAAGACCCAAGTTTTCTCCCTTTTTTAGGGCTAAATTAA

Upstream 100 bases:

>100_bases
TGACCGTCTAGATGTAGCAATCCCCTCACTTTAGCGAGGGGAGGAAATCAATTGTCCTCAGTACTTGTTATTGCATTAAG
CGCTGAAATTAGGAGCTGTC

Downstream 100 bases:

>100_bases
CGCCTGAAGGCCGAACGAAATGTTAAGCGGCTAAGGCAACACCACGTTAATAATTTTCCAGCCAATTAGACCCTCACGCT
GCATCTGTAGCGTCAGCGGG

Product: hypothetical protein

Products: 3-oxo-D 4-steroid; protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSHFLNTLRLICSKSLTLSLAMPVLISALVIMPSAHADLSAFNEAYDKLAANDSRPLKAPTPQQQDFIKQILSNAGMMTP
IASIQPSKLPSMYQITLVQNPSTEPQPPLHITADGAYILQGELKPNPSPVKVPTPQQLPSKTLSGMPVSDDLRASMLKNS
SLLKNMTPDVALYHTAVPGVIWGATLKGQPFITNTEATVFTSGEISVIENGQFAGLDADFEQKKNLHVLSSLDDDNLVIY
PATTTEKAVIYVATDINCPYCRVLHQDMAKLNAKGVTVKVIAYPYYEQSPEQMRQIWCAADKAARKQALDEAMSGKPVNN
TCRSGIDHLKANQVKAAGLAVFATPAIYREDGAAFNAPYKDPSFLPFLGLN

Sequences:

>Translated_371_residues
MSHFLNTLRLICSKSLTLSLAMPVLISALVIMPSAHADLSAFNEAYDKLAANDSRPLKAPTPQQQDFIKQILSNAGMMTP
IASIQPSKLPSMYQITLVQNPSTEPQPPLHITADGAYILQGELKPNPSPVKVPTPQQLPSKTLSGMPVSDDLRASMLKNS
SLLKNMTPDVALYHTAVPGVIWGATLKGQPFITNTEATVFTSGEISVIENGQFAGLDADFEQKKNLHVLSSLDDDNLVIY
PATTTEKAVIYVATDINCPYCRVLHQDMAKLNAKGVTVKVIAYPYYEQSPEQMRQIWCAADKAARKQALDEAMSGKPVNN
TCRSGIDHLKANQVKAAGLAVFATPAIYREDGAAFNAPYKDPSFLPFLGLN
>Mature_370_residues
SHFLNTLRLICSKSLTLSLAMPVLISALVIMPSAHADLSAFNEAYDKLAANDSRPLKAPTPQQQDFIKQILSNAGMMTPI
ASIQPSKLPSMYQITLVQNPSTEPQPPLHITADGAYILQGELKPNPSPVKVPTPQQLPSKTLSGMPVSDDLRASMLKNSS
LLKNMTPDVALYHTAVPGVIWGATLKGQPFITNTEATVFTSGEISVIENGQFAGLDADFEQKKNLHVLSSLDDDNLVIYP
ATTTEKAVIYVATDINCPYCRVLHQDMAKLNAKGVTVKVIAYPYYEQSPEQMRQIWCAADKAARKQALDEAMSGKPVNNT
CRSGIDHLKANQVKAAGLAVFATPAIYREDGAAFNAPYKDPSFLPFLGLN

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=131, Percent_Identity=38.1679389312977, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: NA

Molecular weight: Translated: 40256; Mature: 40124

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHFLNTLRLICSKSLTLSLAMPVLISALVIMPSAHADLSAFNEAYDKLAANDSRPLKAP
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
TPQQQDFIKQILSNAGMMTPIASIQPSKLPSMYQITLVQNPSTEPQPPLHITADGAYILQ
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCEEEEE
GELKPNPSPVKVPTPQQLPSKTLSGMPVSDDLRASMLKNSSLLKNMTPDVALYHTAVPGV
ECCCCCCCCCCCCCCHHCCHHHHCCCCCCHHHHHHHHHCHHHHHHCCCCEEEEEHHCCCC
IWGATLKGQPFITNTEATVFTSGEISVIENGQFAGLDADFEQKKNLHVLSSLDDDNLVIY
EECCCCCCCCEEECCCEEEEECCCEEEEECCEEECCCCCHHHCCCEEEEECCCCCCEEEE
PATTTEKAVIYVATDINCPYCRVLHQDMAKLNAKGVTVKVIAYPYYEQSPEQMRQIWCAA
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHH
DKAARKQALDEAMSGKPVNNTCRSGIDHLKANQVKAAGLAVFATPAIYREDGAAFNAPYK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCCEEEEECCEEEECCCCEECCCCC
DPSFLPFLGLN
CCCCCCCCCCC
>Mature Secondary Structure 
SHFLNTLRLICSKSLTLSLAMPVLISALVIMPSAHADLSAFNEAYDKLAANDSRPLKAP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
TPQQQDFIKQILSNAGMMTPIASIQPSKLPSMYQITLVQNPSTEPQPPLHITADGAYILQ
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCEEEEE
GELKPNPSPVKVPTPQQLPSKTLSGMPVSDDLRASMLKNSSLLKNMTPDVALYHTAVPGV
ECCCCCCCCCCCCCCHHCCHHHHCCCCCCHHHHHHHHHCHHHHHHCCCCEEEEEHHCCCC
IWGATLKGQPFITNTEATVFTSGEISVIENGQFAGLDADFEQKKNLHVLSSLDDDNLVIY
EECCCCCCCCEEECCCEEEEECCCEEEEECCEEECCCCCHHHCCCEEEEECCCCCCEEEE
PATTTEKAVIYVATDINCPYCRVLHQDMAKLNAKGVTVKVIAYPYYEQSPEQMRQIWCAA
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHH
DKAARKQALDEAMSGKPVNNTCRSGIDHLKANQVKAAGLAVFATPAIYREDGAAFNAPYK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCCEEEEECCEEEECCCCEECCCCC
DPSFLPFLGLN
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-oxo-D 5-steroid; protein with reduced SH groups [C]

Specific reaction: 3-oxo-D 5-steroid = 3-oxo-D 4-steroid protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: Isomerases; Intramolecular Oxidoreductases; Transposing S-S Bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8168497 [H]