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The map label for this gene is czcC [H]

Identifier: 148550836

GI number: 148550836

Start: 309141

End: 310208

Strand: Reverse

Name: czcC [H]

Synonym: Swit_5400

Alternate gene names: 148550836

Gene position: 310208-309141 (Counterclockwise)

Preceding gene: NA

Following gene: 148550834

Centisome position: 99.99

GC content: 70.32

Gene sequence:

>1068_bases
ATGAAAAAGTTGATCGCGGCCGTATTGGCTGCGGCGTCCTGCGCATCGATCGCGCAGGCGCAAGCACAGGCGCAACAAGC
GCCGGTCCCGGCTGCGCCAACATCGGCACAGCCCATGCCGGCTTTCACGCTCGATCAGGCCGTGTTGGCGGCAGGTGGGT
CGGCACCGGCCAACGCGGCGGCAGCAGCGGGCATCGAAGCCGCACAGGCTGGACGCTCCGTCGCGGGCCTCCGCCCCAAT
CCGACCTTTCAGGGTCAGGTCGAGAATGTCGTGGGTTCCGGGCCTTATCGGGGGCTGCGGAGCGCTGAAACGACGGTCGG
GGTTGCGATCCCGATCGAGCTGGGCGGCAAGCGAAGCGCGCGTGTCGCCGTCGCCGGCGCGCAGCTATCTCGGGCGCAGC
TCCAAGCCGCGATCGCAGAGGCCGATATCCGCGTGCAGGTGACGCAGCTCTATGTCGAGGCGGTCGCGGCCGAACGCCGC
TTGGCGACGGCACGCGACCAAGCCCGGATCGCGGCGGAAGTCCTGCGCGGCGCCGGGGTCCGCGTTCAGGCGGGCCGGGC
ATCGCCGCTCGAACAGCAGCGCGCCGACGTGGCGCGGATCAACGCGGATGCCAACGTCGAGCGGCTGACGCGGCTTGCGG
AGGCGGCCAGGACCAATCTCGCGCGCCGGATCGGTCGTCCGATAGATGGCGCGCTGGACGTAACACTGCTCGATCGCCTC
CCTGCCGCGACCTTCGGGCCGGTCGCCCCGCCAAGTGCGCAAGGCACGCTGGCGCTGGCGGCGGCCGATGCCGATCTGGC
CATCGCCGACGCCGGCATCCGGCTTGCTCGGGCCAATCGGGTGCCCGACATCAACGTCGGACCGGCGCTGCGGCGACTGG
AAGCGACCAACGACACCGCCGCGGTGTTCGCGATCTCGATCCCGATCCCGGTGTTCAACAATGGCCGGGCCGCCATCGCG
CAGGCGACCGCTGAGCGGACGCGGGCGGACGCGGTGCGGCGCGTAACCGCGCTCGATGTCGAGCAGGCTATGGGTCGTGC
GGCTGAGCGGAACAGGAAAGTGTCATAA

Upstream 100 bases:

>100_bases
ATCGCGCTTGGTCGATCCTGGGCTGAGGCCGCCCACCGCCTGACATCTTCCGCTGGCCGGCATCAGCCGGCTCGACGCAA
TTTGTCAGGATCACCAGATA

Downstream 100 bases:

>100_bases
GGCACTGTTTGGCTCGATACAGCGATAGATGGTGGCCGGGTGAACGTTGAAGGTCCTTGCGACGGCGCTAATGGACTTAC
CCTCGAGAACGAGTTGGCGA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKKLIAAVLAAASCASIAQAQAQAQQAPVPAAPTSAQPMPAFTLDQAVLAAGGSAPANAAAAAGIEAAQAGRSVAGLRPN
PTFQGQVENVVGSGPYRGLRSAETTVGVAIPIELGGKRSARVAVAGAQLSRAQLQAAIAEADIRVQVTQLYVEAVAAERR
LATARDQARIAAEVLRGAGVRVQAGRASPLEQQRADVARINADANVERLTRLAEAARTNLARRIGRPIDGALDVTLLDRL
PAATFGPVAPPSAQGTLALAAADADLAIADAGIRLARANRVPDINVGPALRRLEATNDTAAVFAISIPIPVFNNGRAAIA
QATAERTRADAVRRVTALDVEQAMGRAAERNRKVS

Sequences:

>Translated_355_residues
MKKLIAAVLAAASCASIAQAQAQAQQAPVPAAPTSAQPMPAFTLDQAVLAAGGSAPANAAAAAGIEAAQAGRSVAGLRPN
PTFQGQVENVVGSGPYRGLRSAETTVGVAIPIELGGKRSARVAVAGAQLSRAQLQAAIAEADIRVQVTQLYVEAVAAERR
LATARDQARIAAEVLRGAGVRVQAGRASPLEQQRADVARINADANVERLTRLAEAARTNLARRIGRPIDGALDVTLLDRL
PAATFGPVAPPSAQGTLALAAADADLAIADAGIRLARANRVPDINVGPALRRLEATNDTAAVFAISIPIPVFNNGRAAIA
QATAERTRADAVRRVTALDVEQAMGRAAERNRKVS
>Mature_355_residues
MKKLIAAVLAAASCASIAQAQAQAQQAPVPAAPTSAQPMPAFTLDQAVLAAGGSAPANAAAAAGIEAAQAGRSVAGLRPN
PTFQGQVENVVGSGPYRGLRSAETTVGVAIPIELGGKRSARVAVAGAQLSRAQLQAAIAEADIRVQVTQLYVEAVAAERR
LATARDQARIAAEVLRGAGVRVQAGRASPLEQQRADVARINADANVERLTRLAEAARTNLARRIGRPIDGALDVTLLDRL
PAATFGPVAPPSAQGTLALAAADADLAIADAGIRLARANRVPDINVGPALRRLEATNDTAAVFAISIPIPVFNNGRAAIA
QATAERTRADAVRRVTALDVEQAMGRAAERNRKVS

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 36346; Mature: 36346

Theoretical pI: Translated: 11.54; Mature: 11.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIAAVLAAASCASIAQAQAQAQQAPVPAAPTSAQPMPAFTLDQAVLAAGGSAPANAA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHH
AAAGIEAAQAGRSVAGLRPNPTFQGQVENVVGSGPYRGLRSAETTVGVAIPIELGGKRSA
HHHCHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCC
RVAVAGAQLSRAQLQAAIAEADIRVQVTQLYVEAVAAERRLATARDQARIAAEVLRGAGV
EEEEECHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVQAGRASPLEQQRADVARINADANVERLTRLAEAARTNLARRIGRPIDGALDVTLLDRL
EEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHC
PAATFGPVAPPSAQGTLALAAADADLAIADAGIRLARANRVPDINVGPALRRLEATNDTA
CCCCCCCCCCCCCCCEEEEEECCCCEEEECCCEEEECCCCCCCCCCCHHHHHHHCCCCCE
AVFAISIPIPVFNNGRAAIAQATAERTRADAVRRVTALDVEQAMGRAAERNRKVS
EEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLIAAVLAAASCASIAQAQAQAQQAPVPAAPTSAQPMPAFTLDQAVLAAGGSAPANAA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHH
AAAGIEAAQAGRSVAGLRPNPTFQGQVENVVGSGPYRGLRSAETTVGVAIPIELGGKRSA
HHHCHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCC
RVAVAGAQLSRAQLQAAIAEADIRVQVTQLYVEAVAAERRLATARDQARIAAEVLRGAGV
EEEEECHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVQAGRASPLEQQRADVARINADANVERLTRLAEAARTNLARRIGRPIDGALDVTLLDRL
EEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHC
PAATFGPVAPPSAQGTLALAAADADLAIADAGIRLARANRVPDINVGPALRRLEATNDTA
CCCCCCCCCCCCCCCEEEEEECCCCEEEECCCEEEECCCCCCCCCCCHHHHHHHCCCCCE
AVFAISIPIPVFNNGRAAIAQATAERTRADAVRRVTALDVEQAMGRAAERNRKVS
EEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]