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The map label for this gene is ykoU [H]

Identifier: 148550718

GI number: 148550718

Start: 181186

End: 183162

Strand: Direct

Name: ykoU [H]

Synonym: Swit_5282

Alternate gene names: 148550718

Gene position: 181186-183162 (Clockwise)

Preceding gene: 148550717

Following gene: 148550719

Centisome position: 58.4

GC content: 64.29

Gene sequence:

>1977_bases
ATGCGGTTGCCGCGATCGGCGACACGTGGGGCGTCGGTCGGCGAGCCGAGTCCGGGACGCGCTGGAACGAGTCCGGCGCT
CGCGCACTTTGGACTCCATGAAGAACAACGGCCATCCATCATGGCGCGCATGACCGCAGCGCCAAGGAAAGCGGCTTCCA
CCAGCCGCGCGCCGCCCTTCCGCGCAGTGCAACTCGCAACGCTGGTCGACACGGTTCCTACCGGCAACCGCTGGCTGCAC
GAGATGAAGTATGACGGTTACCGCGTGCTGCTGAGCGTCGGCGGGGGCGAGGCCGTTGCCTATACCCGCTCGGGTCTCGA
CTGGTCGGAGAAGTTTAGCGGACTGGTTGCCGACGCCCTGAAGCTGAAGGTTTCCTCCGCGCTCATCGACGGCGAGGCGG
TCGTGCTCGATGCCGACGGCCGCTCGAGTTTCCAGGCCCTGCAAAACGCGCTCAAAGGGGCGCCGGCTTCGATCGATTAT
TTCGCGTTCGACCTGCTGGAGCTCGACGGCGAGGATCTAACCCAGTTGCCACTCACGGAGCGCAAGGCGAAGCTCGCGAA
GATCCTGCCCAAGGGCAAGTCGCGGTTGCGCTATTCGGATCACATTGCCGGCAATGGCGAGAAGTTGCTCGACCAGTTCT
GCGCGGCGGGCCTCGAAGGGGTGATCTCGAAGCGGGCCGACGGCCGCTATGTCGGCTCGCGATCGGGCGGCTGGCTGAAG
ACCAAATGCATCAAGCGGCAGGAGTTCGTCGTGGTCGGCTGGACCCCTTCGGACAAGTCGCGGTTATTCCGATCGCTGAT
CCTGGGTGTCCATGAGGACGGCGTCCTGCGCTATGCCGGCAAGGTCGGCACCGGCTTCGATACCCAGGAGATCATCGACC
TGATGGCGGTGATGGCGCCGCTCGAGCAGGAGGCGCCGACCGTCAAGGCGCCGCGCGCAGAGGTGCGCGGGGCGCACTGG
CTGCGGCCAACGCTGGTCGCAGAAATTGCATTTACCGAAATGACAAACGAAGGGACCCTCCGGCATCCGTCCTTTCTGGG
CCTGCGAGAAGACAAGAAGCCCGAGGCTGTGGTCGTCGAGACCGAGGCGCCGGTTGAGGCGGTGACGGCCGAGACCTCGT
CGATCAAGATCACCAACCGCGACCGTGTCATTTTTCCCGAAGGGAAGCTTACCAAGGGTCAGCTGGCCGATTATTATACG
CAGGTCGCTCCGATCATGCTGCCCTGGATCGGTTCGCGGCCGATCAGCCTCGTTCGCTGCCCGCAAGGCCGAGCCAAGAA
ATGCTTCTTCCAGAAGCATGACGCGGGCAGTTTTGGCGACGCTGTACGGCATGTCGCCATTCGCGAGAAGGACGGGCACG
ACGAGCCCTATCTCTATGTCGATACCGCGGACGGCCTGCTCACATGCGTACAGATGGGCACGATCGAGTTCCATGGTTGG
GGCGCCAGGATCGAGGATGTCGAGAGGGCCGACCGGCTGGTCTTCGATCTTGATCCCGACGAGGGCCTGGATTTCGAGAA
TGTGCGCAGCGCCGCCTTCCACTTTCGCGAGATCCTGCAGTCGATCGGGCTCGAGACCTTCCCGATGGTGACCGGCGGCA
AGGGCGTCCATGTGATCGCGCCGCTTGTTCCGCAAGCGGAGTGGCCGGAGGTGAAAGACTTTGCGCATCGGCTGGCCCAA
GCGGTTGCCCAGAGTGACCCTGAGCATTTCACGGCCGCCCTGCCGAAAGCGCAGCGCAAGGGCCGCATCTTTGTCGACTA
TCTTCGCAACCAGCGCGGTGCGACGGCGGTCATGCCCTATGGGGTCCGCGCGCGCGAAGGCGCGCCGGTCGCCGTACCCA
TCACATGGAAGGAAATGGAGACGATCGACAAGCCCTCGCACTGGACCATTCGCGATGGCGCCGAACTGGTGAAGCGGGCC
GGCTCCAAGGCGCTCAGCGGTTGGGGCCGCGCCGACCAGACCCTGCCTGACCTGTGA

Upstream 100 bases:

>100_bases
GCGCGATACGCGCGCGGTCCTGGGGCCCGCGAGCGGTCTTGTCGTCTGCCATTGCTCATCTCCTTCGTCGGTGGCCTAGA
TCCGCAACGCCGGGGGGACG

Downstream 100 bases:

>100_bases
AGATCGCCACCTATAATGTGAACGGCGTCAATGGCCGGCTGCCGGTGCTGCTGCGCTGGCTTGAGGAAGCGCAGCCTGAT
GTGGTTGTGCTCCAGGAATT

Product: DNA ligase D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MRLPRSATRGASVGEPSPGRAGTSPALAHFGLHEEQRPSIMARMTAAPRKAASTSRAPPFRAVQLATLVDTVPTGNRWLH
EMKYDGYRVLLSVGGGEAVAYTRSGLDWSEKFSGLVADALKLKVSSALIDGEAVVLDADGRSSFQALQNALKGAPASIDY
FAFDLLELDGEDLTQLPLTERKAKLAKILPKGKSRLRYSDHIAGNGEKLLDQFCAAGLEGVISKRADGRYVGSRSGGWLK
TKCIKRQEFVVVGWTPSDKSRLFRSLILGVHEDGVLRYAGKVGTGFDTQEIIDLMAVMAPLEQEAPTVKAPRAEVRGAHW
LRPTLVAEIAFTEMTNEGTLRHPSFLGLREDKKPEAVVVETEAPVEAVTAETSSIKITNRDRVIFPEGKLTKGQLADYYT
QVAPIMLPWIGSRPISLVRCPQGRAKKCFFQKHDAGSFGDAVRHVAIREKDGHDEPYLYVDTADGLLTCVQMGTIEFHGW
GARIEDVERADRLVFDLDPDEGLDFENVRSAAFHFREILQSIGLETFPMVTGGKGVHVIAPLVPQAEWPEVKDFAHRLAQ
AVAQSDPEHFTAALPKAQRKGRIFVDYLRNQRGATAVMPYGVRAREGAPVAVPITWKEMETIDKPSHWTIRDGAELVKRA
GSKALSGWGRADQTLPDL

Sequences:

>Translated_658_residues
MRLPRSATRGASVGEPSPGRAGTSPALAHFGLHEEQRPSIMARMTAAPRKAASTSRAPPFRAVQLATLVDTVPTGNRWLH
EMKYDGYRVLLSVGGGEAVAYTRSGLDWSEKFSGLVADALKLKVSSALIDGEAVVLDADGRSSFQALQNALKGAPASIDY
FAFDLLELDGEDLTQLPLTERKAKLAKILPKGKSRLRYSDHIAGNGEKLLDQFCAAGLEGVISKRADGRYVGSRSGGWLK
TKCIKRQEFVVVGWTPSDKSRLFRSLILGVHEDGVLRYAGKVGTGFDTQEIIDLMAVMAPLEQEAPTVKAPRAEVRGAHW
LRPTLVAEIAFTEMTNEGTLRHPSFLGLREDKKPEAVVVETEAPVEAVTAETSSIKITNRDRVIFPEGKLTKGQLADYYT
QVAPIMLPWIGSRPISLVRCPQGRAKKCFFQKHDAGSFGDAVRHVAIREKDGHDEPYLYVDTADGLLTCVQMGTIEFHGW
GARIEDVERADRLVFDLDPDEGLDFENVRSAAFHFREILQSIGLETFPMVTGGKGVHVIAPLVPQAEWPEVKDFAHRLAQ
AVAQSDPEHFTAALPKAQRKGRIFVDYLRNQRGATAVMPYGVRAREGAPVAVPITWKEMETIDKPSHWTIRDGAELVKRA
GSKALSGWGRADQTLPDL
>Mature_658_residues
MRLPRSATRGASVGEPSPGRAGTSPALAHFGLHEEQRPSIMARMTAAPRKAASTSRAPPFRAVQLATLVDTVPTGNRWLH
EMKYDGYRVLLSVGGGEAVAYTRSGLDWSEKFSGLVADALKLKVSSALIDGEAVVLDADGRSSFQALQNALKGAPASIDY
FAFDLLELDGEDLTQLPLTERKAKLAKILPKGKSRLRYSDHIAGNGEKLLDQFCAAGLEGVISKRADGRYVGSRSGGWLK
TKCIKRQEFVVVGWTPSDKSRLFRSLILGVHEDGVLRYAGKVGTGFDTQEIIDLMAVMAPLEQEAPTVKAPRAEVRGAHW
LRPTLVAEIAFTEMTNEGTLRHPSFLGLREDKKPEAVVVETEAPVEAVTAETSSIKITNRDRVIFPEGKLTKGQLADYYT
QVAPIMLPWIGSRPISLVRCPQGRAKKCFFQKHDAGSFGDAVRHVAIREKDGHDEPYLYVDTADGLLTCVQMGTIEFHGW
GARIEDVERADRLVFDLDPDEGLDFENVRSAAFHFREILQSIGLETFPMVTGGKGVHVIAPLVPQAEWPEVKDFAHRLAQ
AVAQSDPEHFTAALPKAQRKGRIFVDYLRNQRGATAVMPYGVRAREGAPVAVPITWKEMETIDKPSHWTIRDGAELVKRA
GSKALSGWGRADQTLPDL

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG3285

COG function: function code L; Predicted eukaryotic-type DNA primase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 72114; Mature: 72114

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPRSATRGASVGEPSPGRAGTSPALAHFGLHEEQRPSIMARMTAAPRKAASTSRAPPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCH
RAVQLATLVDTVPTGNRWLHEMKYDGYRVLLSVGGGEAVAYTRSGLDWSEKFSGLVADAL
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHH
KLKVSSALIDGEAVVLDADGRSSFQALQNALKGAPASIDYFAFDLLELDGEDLTQLPLTE
HHHHHHHEECCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHEEEHHHCCCCCCCCCCCHH
RKAKLAKILPKGKSRLRYSDHIAGNGEKLLDQFCAAGLEGVISKRADGRYVGSRSGGWLK
HHHHHHHHCCCCHHHCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEE
TKCIKRQEFVVVGWTPSDKSRLFRSLILGVHEDGVLRYAGKVGTGFDTQEIIDLMAVMAP
HHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
LEQEAPTVKAPRAEVRGAHWLRPTLVAEIAFTEMTNEGTLRHPSFLGLREDKKPEAVVVE
HHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEE
TEAPVEAVTAETSSIKITNRDRVIFPEGKLTKGQLADYYTQVAPIMLPWIGSRPISLVRC
CCCCCHHEECCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEC
PQGRAKKCFFQKHDAGSFGDAVRHVAIREKDGHDEPYLYVDTADGLLTCVQMGTIEFHGW
CCCCCHHHHEECCCCCCHHHHHHHHEEECCCCCCCCEEEEECCCHHHHHHHHCCEEEECC
GARIEDVERADRLVFDLDPDEGLDFENVRSAAFHFREILQSIGLETFPMVTGGKGVHVIA
CCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEE
PLVPQAEWPEVKDFAHRLAQAVAQSDPEHFTAALPKAQRKGRIFVDYLRNQRGATAVMPY
ECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCEEEHHHHCCCCCEEECCC
GVRAREGAPVAVPITWKEMETIDKPSHWTIRDGAELVKRAGSKALSGWGRADQTLPDL
CCCCCCCCCEEEEEEHHHHHHCCCCCCEEECCHHHHHHHCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRLPRSATRGASVGEPSPGRAGTSPALAHFGLHEEQRPSIMARMTAAPRKAASTSRAPPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCH
RAVQLATLVDTVPTGNRWLHEMKYDGYRVLLSVGGGEAVAYTRSGLDWSEKFSGLVADAL
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHH
KLKVSSALIDGEAVVLDADGRSSFQALQNALKGAPASIDYFAFDLLELDGEDLTQLPLTE
HHHHHHHEECCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHEEEHHHCCCCCCCCCCCHH
RKAKLAKILPKGKSRLRYSDHIAGNGEKLLDQFCAAGLEGVISKRADGRYVGSRSGGWLK
HHHHHHHHCCCCHHHCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEE
TKCIKRQEFVVVGWTPSDKSRLFRSLILGVHEDGVLRYAGKVGTGFDTQEIIDLMAVMAP
HHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
LEQEAPTVKAPRAEVRGAHWLRPTLVAEIAFTEMTNEGTLRHPSFLGLREDKKPEAVVVE
HHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEE
TEAPVEAVTAETSSIKITNRDRVIFPEGKLTKGQLADYYTQVAPIMLPWIGSRPISLVRC
CCCCCHHEECCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEC
PQGRAKKCFFQKHDAGSFGDAVRHVAIREKDGHDEPYLYVDTADGLLTCVQMGTIEFHGW
CCCCCHHHHEECCCCCCHHHHHHHHEEECCCCCCCCEEEEECCCHHHHHHHHCCEEEECC
GARIEDVERADRLVFDLDPDEGLDFENVRSAAFHFREILQSIGLETFPMVTGGKGVHVIA
CCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEE
PLVPQAEWPEVKDFAHRLAQAVAQSDPEHFTAALPKAQRKGRIFVDYLRNQRGATAVMPY
ECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCEEEHHHHCCCCCEEECCC
GVRAREGAPVAVPITWKEMETIDKPSHWTIRDGAELVKRAGSKALSGWGRADQTLPDL
CCCCCCCCCEEEEEEHHHHHHCCCCCCEEECCHHHHHHHCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]