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The map label for this gene is katE [H]

Identifier: 148550685

GI number: 148550685

Start: 136172

End: 138379

Strand: Direct

Name: katE [H]

Synonym: Swit_5248

Alternate gene names: 148550685

Gene position: 136172-138379 (Clockwise)

Preceding gene: 148550684

Following gene: 148550686

Centisome position: 43.89

GC content: 64.63

Gene sequence:

>2208_bases
ATGCCCAGGAAACCCGCGACCGACAAAGATGTGCTCGTTCCTGCCGACATTGCGCCTGGCAAGCCCGTCTCGGGAGAGTC
GCGGCAGAAGGCCTCGCCGGTGCCCGCCGACGCACAGCTGTCGGAAAGCTATGCTGAAAAACAGGGAGACGGCGGTGAGA
CCCACCAGGTCGCAGCCGACGGCGCGCCGGTGCTCACCACGGGCCATGGCGCTCCGGTCGCCGACGACCAGAACAGCCTG
AAGCAGGGTGCGCGCGGCCCGACGCTGCTCGAGGACTTCCACTTTCGCGAGAAGATCTTCCACTTCGACCATGAGCGGAT
CCCCGAGCGCGTGGTCCATGCCCGCGGCTATGGCGCGCACGGCTTTTTCGAGCTGACCGACAGCCTGGCGGACGTGACCC
GCGCCGACATCTTCCAGCGCGTTGGCGAGCGCACGCCGGCCTTCGTGCGCTTCTCGACCGTGGCGGGCTCGAAGGGTTCG
TTCGATCTCGCGCGCGATGTGCGCGGCTTCGCCGTCAAGCTCTATACCAAGGAAGGCAACTGGGACCTGGTCGGCAACAA
CATCCCGGTCTTCTTCATCCAGGATGCGATCAAGTTTCCCGACCTCGTCCATGCGGCAAAGCCCGAGCCTGACCGCGCCT
TCCCGCAGGCGCAGACCGCCCATGACAATTTCTGGGATTTCATCAGCCTGACGCCCGAGTCCATGCACATGATCATGTGG
GCCATGTCGGACCGGGCGATCCCGCGCTCGTTCCGCACGATGGAGGGCTTTGGCGTCCATACCTTCCGGCTCGTCAGCGC
CGAGGGCAAGTCGACCTTCGTCAAGTTCCACTGGAAGCCCAAGCAGGGCCTGCAGTCGGTGCTGTGGAACGAGGCGGTCA
AGATCAACGGCGCCGACCCGGACTTCCATCGTCGCGATCTGTGGGAAGCGATCAATGGCGGCGACTTTCCCGAATGGGAG
CTCGGCGTCCAGCTGTTCGACCAGGCCTTTGCCGACCAGTTCGATTTCGACGTGCTCGATGCGACCAAGATCATTCCGGA
AGAGATCCTGCCCGTCCGGGTCGTGGGCCGTCTGGTGCTTGACCGGGTCGTCGACAATTTCTTCGCCGAGACCGAACAGG
TCGCCTTCTGCACGCAGAATGTCGTGCCCGGCATCGACTTCACCAACGACCCGCTGCTCCAGGGGCGTAATTTCTCCTAC
CTCGATACGCAGCTCAAGCGCCTGGGCTCGCCCAACTTCACTCATATCCCGATCAACGCGCCCAAATGCCCCGTGGCCCA
TTTCCAGCAGGACGGGCACATGGCGATGACCAACCCCCGGGGGCGGGTCAATTATGAGCCCAACAGCTGGGGTGCGACGC
TCGGCGGACCGCGCGAGGATCCGGTCCGGGGGTTCCGGAGCTTCGCCGAGGAGGCTGATGGCGCCAAGCTGCGCATCCGC
CCGGAAAGCTTTGCCGATCACTACAGCCAGGCCCGGCAATTCTATGTGAGCCAGGAGCCGATCGAGCAGAAGCATATCGC
CGATGCCCTGGTTTTCGAGCTCAGCAAGGTCGAACGGCCGGACATTCGCGCCCGTGTCGTCTCGCACCTGATCAACATCG
ACGACGGCCTGGCCGGCACCGTCGCGGACGGCCTGGGCCTTCCCGAATTGCCCGCGCCCGCACAGGCCGCGCAGCCGACC
CGGGGCGACTTGCCCCCGTCCGAAGCACTGTCGATCGTGAAGAACGGACCGCCGAGCTTCAAGGGGCGCAAGCTGGGCAT
TCTCCTGAGCGACGGCGCCGATGCCGCGCTGTTTGGCGGCCTCGTCAAGGCGCTCGACAAGGTGGGCGCGGTCTATGACG
TGATCGCTCCCAAGATCGGCGGCGTGACGCTCGATGATGGGACCAAGGTTGCGGCCAAGCAGAAGATCGACGGCGGACCT
TCGGTGCTGTTCGACGCGGTGGCCATCGTCGTCTCGGCCGACGGCGCGGCGCTGCTTGCCGATGACGCCGCCACGCAGGA
CTTCGTGCGCGATGCCTTTGGCCATTGCAAATATATCGGCCTCACGCTCGATGCGCAGCCGATCTTTGCCAATGCCGGCA
TCCTCGAGAAGCTCGACGATGCCTGTATCGAGCTTGGCGCAGCCAAGGATGCCACGGCCTTCGTCGATACGATCGCGGCG
CTGCGCTTTTGGCCCCGCGAACTCAAGGTCGACCTGGATGCCAAATGA

Upstream 100 bases:

>100_bases
CCGGGCCTCGGGAAACTCAAAACCGTTCCGGCGGTTTGTCGTTCACACCCGCCCTGCGTCCCGCAGGGCGGTTTATCGAC
ATGACCTGACAGGAGCTTCT

Downstream 100 bases:

>100_bases
GGCCGGCGATCTGCCGCCCCTGCCCTCGCCCGAGCGGCTGCGCGAACTGATGTTCGATGCGGCGAGGTTGGGGCGGACGG
ACGTGCTACCGGCCCTGCTG

Product: catalase

Products: NA

Alternate protein names: KAT2 [H]

Number of amino acids: Translated: 735; Mature: 734

Protein sequence:

>735_residues
MPRKPATDKDVLVPADIAPGKPVSGESRQKASPVPADAQLSESYAEKQGDGGETHQVAADGAPVLTTGHGAPVADDQNSL
KQGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAHGFFELTDSLADVTRADIFQRVGERTPAFVRFSTVAGSKGS
FDLARDVRGFAVKLYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHAAKPEPDRAFPQAQTAHDNFWDFISLTPESMHMIMW
AMSDRAIPRSFRTMEGFGVHTFRLVSAEGKSTFVKFHWKPKQGLQSVLWNEAVKINGADPDFHRRDLWEAINGGDFPEWE
LGVQLFDQAFADQFDFDVLDATKIIPEEILPVRVVGRLVLDRVVDNFFAETEQVAFCTQNVVPGIDFTNDPLLQGRNFSY
LDTQLKRLGSPNFTHIPINAPKCPVAHFQQDGHMAMTNPRGRVNYEPNSWGATLGGPREDPVRGFRSFAEEADGAKLRIR
PESFADHYSQARQFYVSQEPIEQKHIADALVFELSKVERPDIRARVVSHLINIDDGLAGTVADGLGLPELPAPAQAAQPT
RGDLPPSEALSIVKNGPPSFKGRKLGILLSDGADAALFGGLVKALDKVGAVYDVIAPKIGGVTLDDGTKVAAKQKIDGGP
SVLFDAVAIVVSADGAALLADDAATQDFVRDAFGHCKYIGLTLDAQPIFANAGILEKLDDACIELGAAKDATAFVDTIAA
LRFWPRELKVDLDAK

Sequences:

>Translated_735_residues
MPRKPATDKDVLVPADIAPGKPVSGESRQKASPVPADAQLSESYAEKQGDGGETHQVAADGAPVLTTGHGAPVADDQNSL
KQGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAHGFFELTDSLADVTRADIFQRVGERTPAFVRFSTVAGSKGS
FDLARDVRGFAVKLYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHAAKPEPDRAFPQAQTAHDNFWDFISLTPESMHMIMW
AMSDRAIPRSFRTMEGFGVHTFRLVSAEGKSTFVKFHWKPKQGLQSVLWNEAVKINGADPDFHRRDLWEAINGGDFPEWE
LGVQLFDQAFADQFDFDVLDATKIIPEEILPVRVVGRLVLDRVVDNFFAETEQVAFCTQNVVPGIDFTNDPLLQGRNFSY
LDTQLKRLGSPNFTHIPINAPKCPVAHFQQDGHMAMTNPRGRVNYEPNSWGATLGGPREDPVRGFRSFAEEADGAKLRIR
PESFADHYSQARQFYVSQEPIEQKHIADALVFELSKVERPDIRARVVSHLINIDDGLAGTVADGLGLPELPAPAQAAQPT
RGDLPPSEALSIVKNGPPSFKGRKLGILLSDGADAALFGGLVKALDKVGAVYDVIAPKIGGVTLDDGTKVAAKQKIDGGP
SVLFDAVAIVVSADGAALLADDAATQDFVRDAFGHCKYIGLTLDAQPIFANAGILEKLDDACIELGAAKDATAFVDTIAA
LRFWPRELKVDLDAK
>Mature_734_residues
PRKPATDKDVLVPADIAPGKPVSGESRQKASPVPADAQLSESYAEKQGDGGETHQVAADGAPVLTTGHGAPVADDQNSLK
QGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAHGFFELTDSLADVTRADIFQRVGERTPAFVRFSTVAGSKGSF
DLARDVRGFAVKLYTKEGNWDLVGNNIPVFFIQDAIKFPDLVHAAKPEPDRAFPQAQTAHDNFWDFISLTPESMHMIMWA
MSDRAIPRSFRTMEGFGVHTFRLVSAEGKSTFVKFHWKPKQGLQSVLWNEAVKINGADPDFHRRDLWEAINGGDFPEWEL
GVQLFDQAFADQFDFDVLDATKIIPEEILPVRVVGRLVLDRVVDNFFAETEQVAFCTQNVVPGIDFTNDPLLQGRNFSYL
DTQLKRLGSPNFTHIPINAPKCPVAHFQQDGHMAMTNPRGRVNYEPNSWGATLGGPREDPVRGFRSFAEEADGAKLRIRP
ESFADHYSQARQFYVSQEPIEQKHIADALVFELSKVERPDIRARVVSHLINIDDGLAGTVADGLGLPELPAPAQAAQPTR
GDLPPSEALSIVKNGPPSFKGRKLGILLSDGADAALFGGLVKALDKVGAVYDVIAPKIGGVTLDDGTKVAAKQKIDGGPS
VLFDAVAIVVSADGAALLADDAATQDFVRDAFGHCKYIGLTLDAQPIFANAGILEKLDDACIELGAAKDATAFVDTIAAL
RFWPRELKVDLDAK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=468, Percent_Identity=44.4444444444444, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI48994891, Length=733, Percent_Identity=50.0682128240109, Blast_Score=674, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147792, Length=459, Percent_Identity=44.4444444444444, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25151141, Length=459, Percent_Identity=44.4444444444444, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71998444, Length=486, Percent_Identity=42.1810699588477, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321525, Length=513, Percent_Identity=36.8421052631579, Blast_Score=316, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6320462, Length=493, Percent_Identity=37.1196754563895, Blast_Score=309, Evalue=1e-84,
Organism=Drosophila melanogaster, GI17981717, Length=495, Percent_Identity=40.4040404040404, Blast_Score=361, Evalue=1e-99,
Organism=Drosophila melanogaster, GI19920968, Length=434, Percent_Identity=40.5529953917051, Blast_Score=341, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 80283; Mature: 80152

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKPATDKDVLVPADIAPGKPVSGESRQKASPVPADAQLSESYAEKQGDGGETHQVAAD
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECC
GAPVLTTGHGAPVADDQNSLKQGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAH
CCCEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
GFFELTDSLADVTRADIFQRVGERTPAFVRFSTVAGSKGSFDLARDVRGFAVKLYTKEGN
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHCCCCEEEEEEEECCC
WDLVGNNIPVFFIQDAIKFPDLVHAAKPEPDRAFPQAQTAHDNFWDFISLTPESMHMIMW
EEEECCCCCEEEECCHHCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHEEECHHHHHHHHH
AMSDRAIPRSFRTMEGFGVHTFRLVSAEGKSTFVKFHWKPKQGLQSVLWNEAVKINGADP
HHCCCCCCHHHHHHCCCCCEEEEEEECCCCCEEEEEEECHHHHHHHHHHCCCEEECCCCC
DFHRRDLWEAINGGDFPEWELGVQLFDQAFADQFDFDVLDATKIIPEEILPVRVVGRLVL
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHH
DRVVDNFFAETEQVAFCTQNVVPGIDFTNDPLLQGRNFSYLDTQLKRLGSPNFTHIPINA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCC
PKCPVAHFQQDGHMAMTNPRGRVNYEPNSWGATLGGPREDPVRGFRSFAEEADGAKLRIR
CCCCHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEC
PESFADHYSQARQFYVSQEPIEQKHIADALVFELSKVERPDIRARVVSHLINIDDGLAGT
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHH
VADGLGLPELPAPAQAAQPTRGDLPPSEALSIVKNGPPSFKGRKLGILLSDGADAALFGG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
LVKALDKVGAVYDVIAPKIGGVTLDDGTKVAAKQKIDGGPSVLFDAVAIVVSADGAALLA
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCHHHHHHHHHHEEECCCCEEEE
DDAATQDFVRDAFGHCKYIGLTLDAQPIFANAGILEKLDDACIELGAAKDATAFVDTIAA
CCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LRFWPRELKVDLDAK
HHHCCHHEEEECCCC
>Mature Secondary Structure 
PRKPATDKDVLVPADIAPGKPVSGESRQKASPVPADAQLSESYAEKQGDGGETHQVAAD
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECC
GAPVLTTGHGAPVADDQNSLKQGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAH
CCCEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
GFFELTDSLADVTRADIFQRVGERTPAFVRFSTVAGSKGSFDLARDVRGFAVKLYTKEGN
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHCCCCEEEEEEEECCC
WDLVGNNIPVFFIQDAIKFPDLVHAAKPEPDRAFPQAQTAHDNFWDFISLTPESMHMIMW
EEEECCCCCEEEECCHHCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHEEECHHHHHHHHH
AMSDRAIPRSFRTMEGFGVHTFRLVSAEGKSTFVKFHWKPKQGLQSVLWNEAVKINGADP
HHCCCCCCHHHHHHCCCCCEEEEEEECCCCCEEEEEEECHHHHHHHHHHCCCEEECCCCC
DFHRRDLWEAINGGDFPEWELGVQLFDQAFADQFDFDVLDATKIIPEEILPVRVVGRLVL
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHH
DRVVDNFFAETEQVAFCTQNVVPGIDFTNDPLLQGRNFSYLDTQLKRLGSPNFTHIPINA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCC
PKCPVAHFQQDGHMAMTNPRGRVNYEPNSWGATLGGPREDPVRGFRSFAEEADGAKLRIR
CCCCHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEC
PESFADHYSQARQFYVSQEPIEQKHIADALVFELSKVERPDIRARVVSHLINIDDGLAGT
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHH
VADGLGLPELPAPAQAAQPTRGDLPPSEALSIVKNGPPSFKGRKLGILLSDGADAALFGG
HHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
LVKALDKVGAVYDVIAPKIGGVTLDDGTKVAAKQKIDGGPSVLFDAVAIVVSADGAALLA
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHCCCCCHHHHHHHHHHEEECCCCEEEE
DDAATQDFVRDAFGHCKYIGLTLDAQPIFANAGILEKLDDACIELGAAKDATAFVDTIAA
CCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LRFWPRELKVDLDAK
HHHCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198032; 11481431 [H]