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The map label for this gene is norB [H]

Identifier: 148550639

GI number: 148550639

Start: 90886

End: 93165

Strand: Reverse

Name: norB [H]

Synonym: Swit_5200

Alternate gene names: 148550639

Gene position: 93165-90886 (Counterclockwise)

Preceding gene: 148550640

Following gene: 148550637

Centisome position: 30.03

GC content: 64.47

Gene sequence:

>2280_bases
ATGTCGACGACGAAACGGCTGTGGATCGGCCTGGCTGCCGTCATCTTCGCAGGATTCGCGGTGATGCTGTGGCTCGGGTC
GGACCTTATGCGTACCGCGCCGCCGATCCCCGAACGGGTCGTGACCGCTTCCGGGCGCACCGTCTTCACACGCGACGATA
TCGAGACCGGCCAACAGGTTTGGCAGTCGATGGGCGGCCAGCAGCTCGGCAGCGTGTGGGGTCACGGCGCATTGATCGCG
CCCGACTGGTCCGCCGACTGGCTGCACCGGGAGGCGCTGGCCCAGCTCGACGCCGTTGCCCGCACGAAGGGCGCGGCCAG
CTTCGACATGCTGTCGCTGGCAGATAAGGCGGCTTTGCAGGCCGAGCTACGTCCCGGCTTCCGTGCCAACACCTATGACG
CTGCGACCGGCACGCTGACGATCAGCGACGCGCGCGCTGCAGCGATCGCCGGCGTGGCAAGGCATTATGACAGCCTGTTC
TCCGCTGACCCGGCAACGCGCGATTTGCGCGTCGCCTACGCCATGAAGGAGAACACACTTCCCGATCCGGCGCGGCGCAG
GGAACTCGCGGCCTTCTTCTTCTGGACAGCCTGGGCGACCGTGACCGATCGGCCCGGCGATATGGTGAGCTTTACCAACA
ACTGGCCCTCCGAACCGCTGGTCGGCAACGTGCCCACGTCCGGCACCTTCATGTGGTCGCTTTTCAGCATCCTCTTCATG
CTCGCCGGCATCGGCCTTCTCGCGTGGCACTATGCGGTCTGGCACGGCAAGGAACCGCCGCTCACCCCGCCCGCGGCCGA
TCCGCTCAAGGGGATCGTTCTGACACCCTCGATGCGTGCCAGCGCCAAATATTTCTGGATCGTCATCGCGCTCCTGCTCG
CGCAGATCGGCCTGGGGGCGGCGACCGCGCATTATCAGGTCGAGGGCCAGCATTTCTACGGCATCAACCTCGCCGACTGG
CTACCCTACAGCCTGACTCGAAGCTGGCACACCCAGCTCGCGGTGCTGTGGATCGCGACGGCCTGGCTCGGCACCGGCCT
CTATATCGCGCCCGCCATCTCCGGCCATGAGCCGCCGTGGCAGCGCGCCGGTGTCAACTTCCTGTTCGTCAGCCTGATCG
TCATCGTCGTCGGCGCGTTCGCCGGACAATGGCTGGCGGTGATGCAGAAGATGGGCCTCACCGAAAACTTCTGGTTCGGG
CATCAAGGCTGGGAATATGTCGATCTTGGCCGGTTCTGGCAGATATACCTCTTCATCGGCCTGCTGCTGTGGCTCTTCCT
CGTGGGTCGCGCGCTCTGGCCCGCGATCCGGCGCCGGGATGAGATGTCCTCGATCGTCGGCCTGCTGTTCCTCTCCACGG
TGGCGATCGGTCTCTTCTATGGCGCGGGGCTCATGTATGGCGCGCGCAGCCACCTGTCCGAGGTTGAGTATTGGCGTTGG
TGGGTGGTCCATCTCTGGGTCGAGGGCTTCTTCGAGATTTTCGCGGTCGCCGTCATCAGCTTCCTGTTCGTAAAGCTGGG
GCTGGTGCGCGGCCGCACGGCCACGGTCAATGTGCTGTTCGCGACGATCGTCTTCCTGTCGGGCGGCGTGCTTGGCATGT
TCCACCATCTCTATTTCGTCGGCACGTCGATGGCGGGCGTGGCGCTCGGCGCCAGTTTCTCCGCGCTTGAGGTGGTCCCG
CTCGCGTTAATCGGCCTCGAGGCGATGGACACCTGGTCGCACAGTCGCGCGACGCCGTGGATGGCGCGCTACAAATGGCC
GATCATGTTTTTCCTCGCGGTGAGCTTCTGGAATCTGGTCGGCGCCGGCCTGTTCGGCTTCCTCATCAACACGCCGATCG
CGCTCTATTACGTCCAGGGACTCAACCTGACCCCGCTGCACGGCCATACCGCGCTCTTCGGCGTCTATGGGATGCTCGGC
ATCGGCCTGATGCTCTTCTGCCTGCGCGGCCTGCGCGATCATATCCATTGGAACGAAGGCTGGCTACGCGCGAGCTTCTG
GTGCTTCAACATCGGGCTTGCCCTGATGGCCCTGCTCACGCTGCTGCCGATGGGCGTGCTGCAACTTCAGGCGGCGCTCG
ATCATGGCTACGCCTATGCGCGGTCGGCCGCGTTTATGGATCGGCCGCTGATCCATTTCCTCGTGTGGATGCGCACCCCC
GGCGATGTGGTATTTGCCGCTGGCGCGCTGCTGCTGACGGCGTTTGTCGCGCTGCAATGGCTTCGGCCCATACCGGAAGT
ACCCGCCTCTACTGCAAAGGCGAACGAACAGAGCGTTTGA

Upstream 100 bases:

>100_bases
AGCGTATGCACCGTCTGCTGCTGGCGGCATCGGTCATCGCGCTGATCGGCGCCGTCGGCGGCAGTCACGGGCTTTTCTAA
AGGAAGAGGGACGGGGAACG

Downstream 100 bases:

>100_bases
CTAACACCTACGTGCCGATTTGTGGATATCAGTCAGCCCGTAAAATGACTGCTGTGGTGTAGAGGGAATGCAATTCCCAT
CCTAAGGATGCATAGAGACC

Product: putative nitric-oxide reductase

Products: NA

Alternate protein names: NOR large subunit; Nitric oxide reductase cytochrome b subunit [H]

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MSTTKRLWIGLAAVIFAGFAVMLWLGSDLMRTAPPIPERVVTASGRTVFTRDDIETGQQVWQSMGGQQLGSVWGHGALIA
PDWSADWLHREALAQLDAVARTKGAASFDMLSLADKAALQAELRPGFRANTYDAATGTLTISDARAAAIAGVARHYDSLF
SADPATRDLRVAYAMKENTLPDPARRRELAAFFFWTAWATVTDRPGDMVSFTNNWPSEPLVGNVPTSGTFMWSLFSILFM
LAGIGLLAWHYAVWHGKEPPLTPPAADPLKGIVLTPSMRASAKYFWIVIALLLAQIGLGAATAHYQVEGQHFYGINLADW
LPYSLTRSWHTQLAVLWIATAWLGTGLYIAPAISGHEPPWQRAGVNFLFVSLIVIVVGAFAGQWLAVMQKMGLTENFWFG
HQGWEYVDLGRFWQIYLFIGLLLWLFLVGRALWPAIRRRDEMSSIVGLLFLSTVAIGLFYGAGLMYGARSHLSEVEYWRW
WVVHLWVEGFFEIFAVAVISFLFVKLGLVRGRTATVNVLFATIVFLSGGVLGMFHHLYFVGTSMAGVALGASFSALEVVP
LALIGLEAMDTWSHSRATPWMARYKWPIMFFLAVSFWNLVGAGLFGFLINTPIALYYVQGLNLTPLHGHTALFGVYGMLG
IGLMLFCLRGLRDHIHWNEGWLRASFWCFNIGLALMALLTLLPMGVLQLQAALDHGYAYARSAAFMDRPLIHFLVWMRTP
GDVVFAAGALLLTAFVALQWLRPIPEVPASTAKANEQSV

Sequences:

>Translated_759_residues
MSTTKRLWIGLAAVIFAGFAVMLWLGSDLMRTAPPIPERVVTASGRTVFTRDDIETGQQVWQSMGGQQLGSVWGHGALIA
PDWSADWLHREALAQLDAVARTKGAASFDMLSLADKAALQAELRPGFRANTYDAATGTLTISDARAAAIAGVARHYDSLF
SADPATRDLRVAYAMKENTLPDPARRRELAAFFFWTAWATVTDRPGDMVSFTNNWPSEPLVGNVPTSGTFMWSLFSILFM
LAGIGLLAWHYAVWHGKEPPLTPPAADPLKGIVLTPSMRASAKYFWIVIALLLAQIGLGAATAHYQVEGQHFYGINLADW
LPYSLTRSWHTQLAVLWIATAWLGTGLYIAPAISGHEPPWQRAGVNFLFVSLIVIVVGAFAGQWLAVMQKMGLTENFWFG
HQGWEYVDLGRFWQIYLFIGLLLWLFLVGRALWPAIRRRDEMSSIVGLLFLSTVAIGLFYGAGLMYGARSHLSEVEYWRW
WVVHLWVEGFFEIFAVAVISFLFVKLGLVRGRTATVNVLFATIVFLSGGVLGMFHHLYFVGTSMAGVALGASFSALEVVP
LALIGLEAMDTWSHSRATPWMARYKWPIMFFLAVSFWNLVGAGLFGFLINTPIALYYVQGLNLTPLHGHTALFGVYGMLG
IGLMLFCLRGLRDHIHWNEGWLRASFWCFNIGLALMALLTLLPMGVLQLQAALDHGYAYARSAAFMDRPLIHFLVWMRTP
GDVVFAAGALLLTAFVALQWLRPIPEVPASTAKANEQSV
>Mature_758_residues
STTKRLWIGLAAVIFAGFAVMLWLGSDLMRTAPPIPERVVTASGRTVFTRDDIETGQQVWQSMGGQQLGSVWGHGALIAP
DWSADWLHREALAQLDAVARTKGAASFDMLSLADKAALQAELRPGFRANTYDAATGTLTISDARAAAIAGVARHYDSLFS
ADPATRDLRVAYAMKENTLPDPARRRELAAFFFWTAWATVTDRPGDMVSFTNNWPSEPLVGNVPTSGTFMWSLFSILFML
AGIGLLAWHYAVWHGKEPPLTPPAADPLKGIVLTPSMRASAKYFWIVIALLLAQIGLGAATAHYQVEGQHFYGINLADWL
PYSLTRSWHTQLAVLWIATAWLGTGLYIAPAISGHEPPWQRAGVNFLFVSLIVIVVGAFAGQWLAVMQKMGLTENFWFGH
QGWEYVDLGRFWQIYLFIGLLLWLFLVGRALWPAIRRRDEMSSIVGLLFLSTVAIGLFYGAGLMYGARSHLSEVEYWRWW
VVHLWVEGFFEIFAVAVISFLFVKLGLVRGRTATVNVLFATIVFLSGGVLGMFHHLYFVGTSMAGVALGASFSALEVVPL
ALIGLEAMDTWSHSRATPWMARYKWPIMFFLAVSFWNLVGAGLFGFLINTPIALYYVQGLNLTPLHGHTALFGVYGMLGI
GLMLFCLRGLRDHIHWNEGWLRASFWCFNIGLALMALLTLLPMGVLQLQAALDHGYAYARSAAFMDRPLIHFLVWMRTPG
DVVFAAGALLLTAFVALQWLRPIPEVPASTAKANEQSV

Specific function: Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen red

COG id: COG3256

COG function: function code P; Nitric oxide reductase large subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.7.99.7 [H]

Molecular weight: Translated: 84004; Mature: 83873

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTKRLWIGLAAVIFAGFAVMLWLGSDLMRTAPPIPERVVTASGRTVFTRDDIETGQQV
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHEECCCCEEEECCCHHHHHHH
WQSMGGQQLGSVWGHGALIAPDWSADWLHREALAQLDAVARTKGAASFDMLSLADKAALQ
HHHCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AELRPGFRANTYDAATGTLTISDARAAAIAGVARHYDSLFSADPATRDLRVAYAMKENTL
HHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCCCC
PDPARRRELAAFFFWTAWATVTDRPGDMVSFTNNWPSEPLVGNVPTSGTFMWSLFSILFM
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LAGIGLLAWHYAVWHGKEPPLTPPAADPLKGIVLTPSMRASAKYFWIVIALLLAQIGLGA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
ATAHYQVEGQHFYGINLADWLPYSLTRSWHTQLAVLWIATAWLGTGLYIAPAISGHEPPW
EEEEEEECCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCH
QRAGVNFLFVSLIVIVVGAFAGQWLAVMQKMGLTENFWFGHQGWEYVDLGRFWQIYLFIG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
LLLWLFLVGRALWPAIRRRDEMSSIVGLLFLSTVAIGLFYGAGLMYGARSHLSEVEYWRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVVHLWVEGFFEIFAVAVISFLFVKLGLVRGRTATVNVLFATIVFLSGGVLGMFHHLYFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GTSMAGVALGASFSALEVVPLALIGLEAMDTWSHSRATPWMARYKWPIMFFLAVSFWNLV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GAGLFGFLINTPIALYYVQGLNLTPLHGHTALFGVYGMLGIGLMLFCLRGLRDHIHWNEG
HHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WLRASFWCFNIGLALMALLTLLPMGVLQLQAALDHGYAYARSAAFMDRPLIHFLVWMRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
GDVVFAAGALLLTAFVALQWLRPIPEVPASTAKANEQSV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STTKRLWIGLAAVIFAGFAVMLWLGSDLMRTAPPIPERVVTASGRTVFTRDDIETGQQV
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHEECCCCEEEECCCHHHHHHH
WQSMGGQQLGSVWGHGALIAPDWSADWLHREALAQLDAVARTKGAASFDMLSLADKAALQ
HHHCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AELRPGFRANTYDAATGTLTISDARAAAIAGVARHYDSLFSADPATRDLRVAYAMKENTL
HHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCCCC
PDPARRRELAAFFFWTAWATVTDRPGDMVSFTNNWPSEPLVGNVPTSGTFMWSLFSILFM
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LAGIGLLAWHYAVWHGKEPPLTPPAADPLKGIVLTPSMRASAKYFWIVIALLLAQIGLGA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
ATAHYQVEGQHFYGINLADWLPYSLTRSWHTQLAVLWIATAWLGTGLYIAPAISGHEPPW
EEEEEEECCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCH
QRAGVNFLFVSLIVIVVGAFAGQWLAVMQKMGLTENFWFGHQGWEYVDLGRFWQIYLFIG
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
LLLWLFLVGRALWPAIRRRDEMSSIVGLLFLSTVAIGLFYGAGLMYGARSHLSEVEYWRW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVVHLWVEGFFEIFAVAVISFLFVKLGLVRGRTATVNVLFATIVFLSGGVLGMFHHLYFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GTSMAGVALGASFSALEVVPLALIGLEAMDTWSHSRATPWMARYKWPIMFFLAVSFWNLV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GAGLFGFLINTPIALYYVQGLNLTPLHGHTALFGVYGMLGIGLMLFCLRGLRDHIHWNEG
HHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WLRASFWCFNIGLALMALLTLLPMGVLQLQAALDHGYAYARSAAFMDRPLIHFLVWMRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
GDVVFAAGALLLTAFVALQWLRPIPEVPASTAKANEQSV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7711073; 10984043 [H]