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The map label for this gene is stc [H]

Identifier: 148550572

GI number: 148550572

Start: 22271

End: 24025

Strand: Reverse

Name: stc [H]

Synonym: Swit_5133

Alternate gene names: 148550572

Gene position: 24025-22271 (Counterclockwise)

Preceding gene: 148550573

Following gene: 148550571

Centisome position: 7.74

GC content: 59.77

Gene sequence:

>1755_bases
ATGGCGGCGCCTGGCGAACGCCGGATCGCCACAGAAAGGGGTGAACGGCTCATTCGCTATGCGATGCCGGAGATGACACG
GCTTTACAAAGCGTTTCACACGCAGGATTGGGTGCTGGCCTGCCTTGACGTCAGCGGATTTGTCATTTGCTCGATCGGCG
ACGCCGAAGGGCCGTGCCGCGAACTGGAGAGTCTTTTCCGGAACGGGGTTTCCCTCAGCGAAAGTGCGATCGGCACCGGA
GCGCCGGGATGCGCGCTCGTGGAACAGAAACCCTTTATTGTCCACGCCAACGAGCATTTCCTTGACGAGATTCATGGCTA
TTCTTGCGCGGCCGTTCCTCTGTTCGACGTTAACGGGGACCTGATCGGCGTCTTGAATGCCACCTGCCGCAGCGGCAGGG
ATCTGTCATCAGTTTGCGAGGCGTTGCGGGTTGCCGCCCGAGCCATAGAAAATCATATGCTGCTTGACCTTCCGGGCGCT
CTGCACGTCTCGTTACATTATCACCCTGACCTGCTTCGCACGCCCTTGGCTGCCGTTCTCGCTTTCTCGGAACATGGGCA
ATTGCTCGGTGGGAACCAGATCGCGCGCAAGCTGCTTGGGCATACGCGTTCGGCGACAGAGTTCGATCACATGTTCGACC
TGCCTTTTGCGCGTGCGGTTGACGAGCTTAGCGGCCGCAATGCCGAACCGATCGTGACAGACACGCCGGCCGGCATCCGC
GTCCACCTCAGTCTCGCCCGCCATGCAGATGACGTTATGCGGGTTGGTAAGGCGCTCTTGCCGCCGCCCTCGGGCAAGCG
TTCGTCTCATGCCTCTTCTGACATGTTCTGTTCCGATCCCGCCCTGCTGGACACCATTGGCGACGCGAAGCTGGCGTTCG
CTCGTGATATTCCTGTTCTCCTAACCGGCGAGACGGGAACTGGAAAGGAGGTTCTTGCGCGGGAGCTGCACGCCTCAGGG
CCGCGGCGAAACGGGCCGTTCGTGCCGGTAAATTGTGCGTCCATTCCCGACGGACTGATCGAGGCCGAATTGTTCGGATA
TGTGGAAGGGGCGTTTACCGGCGCTCGCCGGGGAGGCGCTCCGGGTAAATTTGAGCAGGCCCATGGTGGAACACTCTTCC
TGGATGAGATCGGGGACATGCCGCTCTCGCTACAGGCTCGTCTTCTGCGGGTTCTGCAGGAGCGGGCCGTCATGCCGGTG
GGCGGATCGAAGGACAGGCCGATCGATATCTCTCTGGTCTGTGCGACCCATCGTGACCTCAAGGCGCTCGTCGCCACGGG
CGAATTTCGGGAAGACCTTTACTACCGCATTGATGGACTCTGCGTCACCTTGCCCCCCTTACGCGAGCGAGCGGATTTGT
CGGAACTCATAGGACAAATCGTCGATCGCGAAATCGGCGATCGTTTGACACTTTCCCTCTCGGATGACGCACTGGAATGT
CTGCGGTCCTTCGCATGGCCCGGGAACATCCGCCAACTGAGCCTCATTCTTCGTCGGGCCATCGCGCTCGCTGCCGGGAG
CGCGCTGATCGCGCCAAGGCATCTTCCAGAGGAGATGAGGCAAACTCGTTCGAATGTGGGGCGCGAGGTGGCTTCGCTCG
AACGAACGGAGCGGGATGCGGTATTAATGGCGCTCCATCAATGTGCGGGAAATATTGCCGCTACGGCTCGTCAATTGGGG
GTCGGCCGGCCGACGCTTTATCGTAAGATGCGTAAGTATAATATCGAAGTGCAGGGCGTTAAGACCATATTTTAA

Upstream 100 bases:

>100_bases
CGAGAGTATCGTGTCGCAGTGGGTGCCCGAGCCGATCACGCGTTCCTGGGAGCGATCAAGACGCCTGGGTTTGAGCGCGT
CCGACAAGAGGTTGTTCGAC

Downstream 100 bases:

>100_bases
CTCTCCATGACGTGTTAGTTGGTTGCGCATTAGCCTTACCGCAAGGTTTTTCGGTTATTTGCGCGAAACAGATAAATGAG
AATCATTACGTAGATTTGAT

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MAAPGERRIATERGERLIRYAMPEMTRLYKAFHTQDWVLACLDVSGFVICSIGDAEGPCRELESLFRNGVSLSESAIGTG
APGCALVEQKPFIVHANEHFLDEIHGYSCAAVPLFDVNGDLIGVLNATCRSGRDLSSVCEALRVAARAIENHMLLDLPGA
LHVSLHYHPDLLRTPLAAVLAFSEHGQLLGGNQIARKLLGHTRSATEFDHMFDLPFARAVDELSGRNAEPIVTDTPAGIR
VHLSLARHADDVMRVGKALLPPPSGKRSSHASSDMFCSDPALLDTIGDAKLAFARDIPVLLTGETGTGKEVLARELHASG
PRRNGPFVPVNCASIPDGLIEAELFGYVEGAFTGARRGGAPGKFEQAHGGTLFLDEIGDMPLSLQARLLRVLQERAVMPV
GGSKDRPIDISLVCATHRDLKALVATGEFREDLYYRIDGLCVTLPPLRERADLSELIGQIVDREIGDRLTLSLSDDALEC
LRSFAWPGNIRQLSLILRRAIALAAGSALIAPRHLPEEMRQTRSNVGREVASLERTERDAVLMALHQCAGNIAATARQLG
VGRPTLYRKMRKYNIEVQGVKTIF

Sequences:

>Translated_584_residues
MAAPGERRIATERGERLIRYAMPEMTRLYKAFHTQDWVLACLDVSGFVICSIGDAEGPCRELESLFRNGVSLSESAIGTG
APGCALVEQKPFIVHANEHFLDEIHGYSCAAVPLFDVNGDLIGVLNATCRSGRDLSSVCEALRVAARAIENHMLLDLPGA
LHVSLHYHPDLLRTPLAAVLAFSEHGQLLGGNQIARKLLGHTRSATEFDHMFDLPFARAVDELSGRNAEPIVTDTPAGIR
VHLSLARHADDVMRVGKALLPPPSGKRSSHASSDMFCSDPALLDTIGDAKLAFARDIPVLLTGETGTGKEVLARELHASG
PRRNGPFVPVNCASIPDGLIEAELFGYVEGAFTGARRGGAPGKFEQAHGGTLFLDEIGDMPLSLQARLLRVLQERAVMPV
GGSKDRPIDISLVCATHRDLKALVATGEFREDLYYRIDGLCVTLPPLRERADLSELIGQIVDREIGDRLTLSLSDDALEC
LRSFAWPGNIRQLSLILRRAIALAAGSALIAPRHLPEEMRQTRSNVGREVASLERTERDAVLMALHQCAGNIAATARQLG
VGRPTLYRKMRKYNIEVQGVKTIF
>Mature_583_residues
AAPGERRIATERGERLIRYAMPEMTRLYKAFHTQDWVLACLDVSGFVICSIGDAEGPCRELESLFRNGVSLSESAIGTGA
PGCALVEQKPFIVHANEHFLDEIHGYSCAAVPLFDVNGDLIGVLNATCRSGRDLSSVCEALRVAARAIENHMLLDLPGAL
HVSLHYHPDLLRTPLAAVLAFSEHGQLLGGNQIARKLLGHTRSATEFDHMFDLPFARAVDELSGRNAEPIVTDTPAGIRV
HLSLARHADDVMRVGKALLPPPSGKRSSHASSDMFCSDPALLDTIGDAKLAFARDIPVLLTGETGTGKEVLARELHASGP
RRNGPFVPVNCASIPDGLIEAELFGYVEGAFTGARRGGAPGKFEQAHGGTLFLDEIGDMPLSLQARLLRVLQERAVMPVG
GSKDRPIDISLVCATHRDLKALVATGEFREDLYYRIDGLCVTLPPLRERADLSELIGQIVDREIGDRLTLSLSDDALECL
RSFAWPGNIRQLSLILRRAIALAAGSALIAPRHLPEEMRQTRSNVGREVASLERTERDAVLMALHQCAGNIAATARQLGV
GRPTLYRKMRKYNIEVQGVKTIF

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=324, Percent_Identity=40.7407407407407, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789233, Length=296, Percent_Identity=40.2027027027027, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1788905, Length=305, Percent_Identity=37.7049180327869, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=38.9057750759878, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=40.2640264026403, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=40, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=38.1656804733728, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789087, Length=304, Percent_Identity=39.1447368421053, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI87082152, Length=336, Percent_Identity=35.4166666666667, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081858, Length=575, Percent_Identity=28.5217391304348, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081872, Length=210, Percent_Identity=44.7619047619048, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=35.126582278481, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1789828, Length=297, Percent_Identity=35.6902356902357, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 63447; Mature: 63316

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPGERRIATERGERLIRYAMPEMTRLYKAFHTQDWVLACLDVSGFVICSIGDAEGPCR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCHHH
ELESLFRNGVSLSESAIGTGAPGCALVEQKPFIVHANEHFLDEIHGYSCAAVPLFDVNGD
HHHHHHHCCCCCCHHCCCCCCCCCEEECCCCEEEECCHHHHHHHCCCCEEEEEEEECCCC
LIGVLNATCRSGRDLSSVCEALRVAARAIENHMLLDLPGALHVSLHYHPDLLRTPLAAVL
EEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCEEEEEEEECCHHHHHHHHHHH
AFSEHGQLLGGNQIARKLLGHTRSATEFDHMFDLPFARAVDELSGRNAEPIVTDTPAGIR
HHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEECCCCCEE
VHLSLARHADDVMRVGKALLPPPSGKRSSHASSDMFCSDPALLDTIGDAKLAFARDIPVL
EEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEHCCCCCEE
LTGETGTGKEVLARELHASGPRRNGPFVPVNCASIPDGLIEAELFGYVEGAFTGARRGGA
EECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PGKFEQAHGGTLFLDEIGDMPLSLQARLLRVLQERAVMPVGGSKDRPIDISLVCATHRDL
CCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHH
KALVATGEFREDLYYRIDGLCVTLPPLRERADLSELIGQIVDREIGDRLTLSLSDDALEC
HHHHHCCHHHHHHHHEECCEEEECCCCHHHCCHHHHHHHHHHHHCCCEEEEEECHHHHHH
LRSFAWPGNIRQLSLILRRAIALAAGSALIAPRHLPEEMRQTRSNVGREVASLERTERDA
HHHHCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLMALHQCAGNIAATARQLGVGRPTLYRKMRKYNIEVQGVKTIF
HHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure 
AAPGERRIATERGERLIRYAMPEMTRLYKAFHTQDWVLACLDVSGFVICSIGDAEGPCR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCHHH
ELESLFRNGVSLSESAIGTGAPGCALVEQKPFIVHANEHFLDEIHGYSCAAVPLFDVNGD
HHHHHHHCCCCCCHHCCCCCCCCCEEECCCCEEEECCHHHHHHHCCCCEEEEEEEECCCC
LIGVLNATCRSGRDLSSVCEALRVAARAIENHMLLDLPGALHVSLHYHPDLLRTPLAAVL
EEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCEEEEEEEECCHHHHHHHHHHH
AFSEHGQLLGGNQIARKLLGHTRSATEFDHMFDLPFARAVDELSGRNAEPIVTDTPAGIR
HHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEECCCCCEE
VHLSLARHADDVMRVGKALLPPPSGKRSSHASSDMFCSDPALLDTIGDAKLAFARDIPVL
EEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEHCCCCCEE
LTGETGTGKEVLARELHASGPRRNGPFVPVNCASIPDGLIEAELFGYVEGAFTGARRGGA
EECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PGKFEQAHGGTLFLDEIGDMPLSLQARLLRVLQERAVMPVGGSKDRPIDISLVCATHRDL
CCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHH
KALVATGEFREDLYYRIDGLCVTLPPLRERADLSELIGQIVDREIGDRLTLSLSDDALEC
HHHHHCCHHHHHHHHEECCEEEECCCCHHHCCHHHHHHHHHHHHCCCEEEEEECHHHHHH
LRSFAWPGNIRQLSLILRRAIALAAGSALIAPRHLPEEMRQTRSNVGREVASLERTERDA
HHHHCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLMALHQCAGNIAATARQLGVGRPTLYRKMRKYNIEVQGVKTIF
HHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA