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The map label for this gene is murG

Identifier: 148380719

GI number: 148380719

Start: 2914702

End: 2915766

Strand: Reverse

Name: murG

Synonym: CBO2761

Alternate gene names: 148380719

Gene position: 2915766-2914702 (Counterclockwise)

Preceding gene: 148380721

Following gene: 148380718

Centisome position: 75.01

GC content: 28.83

Gene sequence:

>1065_bases
TTGAAAAAGATTATAATGACAGGTGGAGGAACAGCAGGCCATGTTACACCAAATTTAGCTTTAGTTCCAGAATTGAAAAA
ATTAGGCTATGAAATAAAGTATATAGGGAGCATAGAAGGAATAGAAAGAAAAATTATAGAAAAAGAAGGGATAGAATATT
TCCCCATCTCTAGTGGAAAATTAAGAAGATACTTTGATTTGAAAAATTTCTCTGATCCATTTAAAGTGCTAAAGGGAGTG
TTTCAAGCAAAAAAAATAATTAAAAGAGAAAAACCAGATATAGTTTTTTCAAAGGGCGGGTTTGTAACTGTGCCAGTAGT
TATAGCAGCTCATTTAAATAAAATACCAGTTATAGCTCATGAGTCAGATATAACTCCAGGTCTTGCAAATAAATTAGCTA
CTCCTTATTGTACAAGGGTATGCGTTACTTTTCCAGAGTCAGTAAAACATATAAAAGGAGATAAAGCTGTATTAACAGGT
ACACCTATAAGAAGAGAATTATTAGAAGGAAATAAGCTTGAAGGTATAAAGTTATGTGGATTTAAAGATAATAAACCTAT
TCTTTTAATAATTGGAGGAAGTTTAGGTTCGAAAATTATAAACGAAATAGTCAGAAAAAATCTGGACAATATACTTTCAA
AATTCAATATAATACACATTTGCGGAAAGTCTAACTTAGATGAAAATTTAGAAAATAGAAAGGGATATGCTCAATTTGAG
TATGTAAATGAAGAGCTACCAGATTTAATGAAAGCGTCAGATTTAGTAATATCAAGAGCAGGAGCAAATGTAATATATGA
ACTTTTAGCACTTAAAAAGCCAAATCTTTTAATACCTTTATCTAAAAAATCTAGTAGAGGGGACCAAATTTTAAATGCAG
CTTCCTTTGAAAAAAGTGGCTATAGTTTAGTTTTAAAGGAGGAAGAGCTTGAAGATAAAACCTTAATAAAAAAGTTAAAT
TATTTGTATGAAAACAGAAATGTATATATAAATAATATGTCCAAAAGTAAAATGGATAATGGCGTTAAAAATATAACAGA
ATTGATAAAAAAATATACAAAATAA

Upstream 100 bases:

>100_bases
ATTTTTTCTTTGGAAGAAATTTTACTGAAACTAATAATGATTTACAAAAAATAAAAATTAAGTTATATACATAATGAATT
AAAGAAAGGGGAATATAATT

Downstream 100 bases:

>100_bases
ATATATGGTATTAAAATTAAAGCTAAATTAAACTAATCTTGCATAGTTTAATAAATTCAAAAAAGAATATATATTAAGTT
AAATATAGAATAATAATTTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKKIIMTGGGTAGHVTPNLALVPELKKLGYEIKYIGSIEGIERKIIEKEGIEYFPISSGKLRRYFDLKNFSDPFKVLKGV
FQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAHESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTG
TPIRRELLEGNKLEGIKLCGFKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFE
YVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSGYSLVLKEEELEDKTLIKKLN
YLYENRNVYINNMSKSKMDNGVKNITELIKKYTK

Sequences:

>Translated_354_residues
MKKIIMTGGGTAGHVTPNLALVPELKKLGYEIKYIGSIEGIERKIIEKEGIEYFPISSGKLRRYFDLKNFSDPFKVLKGV
FQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAHESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTG
TPIRRELLEGNKLEGIKLCGFKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFE
YVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSGYSLVLKEEELEDKTLIKKLN
YLYENRNVYINNMSKSKMDNGVKNITELIKKYTK
>Mature_354_residues
MKKIIMTGGGTAGHVTPNLALVPELKKLGYEIKYIGSIEGIERKIIEKEGIEYFPISSGKLRRYFDLKNFSDPFKVLKGV
FQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAHESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTG
TPIRRELLEGNKLEGIKLCGFKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFE
YVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSGYSLVLKEEELEDKTLIKKLN
YLYENRNVYINNMSKSKMDNGVKNITELIKKYTK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=314, Percent_Identity=29.6178343949045, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CLOB1 (A7FX11)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385003.1
- ProteinModelPortal:   A7FX11
- SMR:   A7FX11
- STRING:   A7FX11
- GeneID:   5395928
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2702
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK00726
- BioCyc:   CBOT441770:CLB_2702-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39608; Mature: 39608

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIMTGGGTAGHVTPNLALVPELKKLGYEIKYIGSIEGIERKIIEKEGIEYFPISSGK
CCEEEEECCCCCCCCCCCEEECCHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEECCCCC
LRRYFDLKNFSDPFKVLKGVFQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAH
CEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHCCCCCEEEE
ESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTGTPIRRELLEGNKLEGIKLCG
CCCCCCHHHHHHCCHHHHHHHEECCHHHHHCCCCCEEEECCHHHHHHHCCCCCCCEEEEC
FKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFE
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCCCCHHH
YVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCC
YSLVLKEEELEDKTLIKKLNYLYENRNVYINNMSKSKMDNGVKNITELIKKYTK
CEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIIMTGGGTAGHVTPNLALVPELKKLGYEIKYIGSIEGIERKIIEKEGIEYFPISSGK
CCEEEEECCCCCCCCCCCEEECCHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEECCCCC
LRRYFDLKNFSDPFKVLKGVFQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAH
CEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHCCCCCEEEE
ESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTGTPIRRELLEGNKLEGIKLCG
CCCCCCHHHHHHCCHHHHHHHEECCHHHHHCCCCCEEEECCHHHHHHHCCCCCCCEEEEC
FKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFE
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCCCCHHH
YVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCC
YSLVLKEEELEDKTLIKKLNYLYENRNVYINNMSKSKMDNGVKNITELIKKYTK
CEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA