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The map label for this gene is flhF [H]

Identifier: 148380602

GI number: 148380602

Start: 2795795

End: 2797021

Strand: Reverse

Name: flhF [H]

Synonym: CBO2644

Alternate gene names: 148380602

Gene position: 2797021-2795795 (Counterclockwise)

Preceding gene: 148380603

Following gene: 148380601

Centisome position: 71.96

GC content: 27.06

Gene sequence:

>1227_bases
ATGAAAATAAAAAAATATGTAGTCAATGATATGAATGAAGCAATGACTAGAATTCGTTATGAACTTGGAGCAGATGCTAT
AATAATAAGTCAAAGAAAAATAAGAAAGGGAGGCTTTTTAGGCCTCTTTTCTAAAAAATCCTTAGAAGTTACTGCAGCTA
TAGATAATTATTCAACAGAAAAAAAATATAACTCTAATACTGTAAATAAAATTAATAAGGGAAATAATATAGAAGTTATT
AAAAGGATGCTAGAAGAAAGAAATAATAATGTTAAATATGATAACAACATAAATCATGATACTAATGCATTAGATAGATA
TAAGGAAATTTTAGAATCTAAAAGTGAAGGCGCCCAAAATAAGAGTCTTAAAGGAAAAAAGTTTTCAGAATCAAAAGATT
TAATGGATGAAATAAGAGATTTAAAGAAAATAGTTAAGGATATAGGAAAAAGCGAAAAATCTTATGCAGATGAAAATTCC
TCATTAGTGAAATTTTTTAAGGATTTGGACTTAGAAGAAGAATTTATTGAAGAAATAATAAAAAAAGTAGGTAATTTAGA
GGAGAATTTAGAAGAAAGAGAGAAAATAAAAAGAGTAATAGAAGATACTATAGATGTTAGAGTGAATTCTGTAGGTAAGG
TTACTGTCTTGGTAGGGCCTACTGGTGTGGGTAAAACTACAACAATTGCAAAGTTAGCAGGTAAGCTTTCTTTAATAGAT
AAAAAGAAAGTAGGTCTCATAACTATAGATACCTATAGAATAGGTGCAGTAGAACAACTAAAAACTTACGCAGATATTAT
GAATATTCCATTTAAAGTAGTATTTTCTATTAAGGATATGGAAAAAGCTATTATAGATTTAGACTATTGTGATGTTATAT
TAGTAGATACTACAGGGAGAAGTAGTAAAAATATGATGCAGATATCAGAGTTAAGGGCTTTTATAGAAAAAATAAAAGAA
AAATCAGTGCATTTAGTAATCAGTGCCTCTACTAAAAATAAGGATATAGAAACTATAGTAAAAGGGTATTCTATTTTAGA
ATATGAAAATATAATAATAACAAAGCTAGATGAAACTAGTATCTATGGTTCAATTTTAACTATATTAGATAAAGGTAAAA
ATCCTATTAGTTTTATAACCACAGGTCAAGATGTACCAGATGATATAAAGGAAGGAAACAAAGAGGAAATAGCAAAGATT
GTATTAGGAGAGAATAAATTATGCTAG

Upstream 100 bases:

>100_bases
GAAGGCTTATAGAGATGGTATTTCCAGCGGTGAACGTACTTTCTTTAAATGAGGTACCTAACGATGTGGAGATAAGAACT
GAAGGAGTGGTTACGCTACA

Downstream 100 bases:

>100_bases
ACCAGGCAGAAAAACTTAGACAATTAGTAAATAATAAGGCTGGAAGCGTAAATTCCCCTAAAATAATTACAGTAACATCT
GGTAAAGGAGGAGTGGGAAA

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKIRKGGFLGLFSKKSLEVTAAIDNYSTEKKYNSNTVNKINKGNNIEVI
KRMLEERNNNVKYDNNINHDTNALDRYKEILESKSEGAQNKSLKGKKFSESKDLMDEIRDLKKIVKDIGKSEKSYADENS
SLVKFFKDLDLEEEFIEEIIKKVGNLEENLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSIKDMEKAIIDLDYCDVILVDTTGRSSKNMMQISELRAFIEKIKE
KSVHLVISASTKNKDIETIVKGYSILEYENIIITKLDETSIYGSILTILDKGKNPISFITTGQDVPDDIKEGNKEEIAKI
VLGENKLC

Sequences:

>Translated_408_residues
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKIRKGGFLGLFSKKSLEVTAAIDNYSTEKKYNSNTVNKINKGNNIEVI
KRMLEERNNNVKYDNNINHDTNALDRYKEILESKSEGAQNKSLKGKKFSESKDLMDEIRDLKKIVKDIGKSEKSYADENS
SLVKFFKDLDLEEEFIEEIIKKVGNLEENLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSIKDMEKAIIDLDYCDVILVDTTGRSSKNMMQISELRAFIEKIKE
KSVHLVISASTKNKDIETIVKGYSILEYENIIITKLDETSIYGSILTILDKGKNPISFITTGQDVPDDIKEGNKEEIAKI
VLGENKLC
>Mature_408_residues
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKIRKGGFLGLFSKKSLEVTAAIDNYSTEKKYNSNTVNKINKGNNIEVI
KRMLEERNNNVKYDNNINHDTNALDRYKEILESKSEGAQNKSLKGKKFSESKDLMDEIRDLKKIVKDIGKSEKSYADENS
SLVKFFKDLDLEEEFIEEIIKKVGNLEENLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSIKDMEKAIIDLDYCDVILVDTTGRSSKNMMQISELRAFIEKIKE
KSVHLVISASTKNKDIETIVKGYSILEYENIIITKLDETSIYGSILTILDKGKNPISFITTGQDVPDDIKEGNKEEIAKI
VLGENKLC

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=258, Percent_Identity=28.6821705426357, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789874, Length=199, Percent_Identity=32.1608040201005, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788963, Length=201, Percent_Identity=28.3582089552239, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17539958, Length=183, Percent_Identity=31.6939890710383, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325345, Length=197, Percent_Identity=31.4720812182741, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647949, Length=199, Percent_Identity=29.6482412060301, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 46173; Mature: 46173

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKIRKGGFLGLFSKKSLEVTAAIDNYSTE
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCEEEEECCCCEEEEEEECCCCCC
KKYNSNTVNKINKGNNIEVIKRMLEERNNNVKYDNNINHDTNALDRYKEILESKSEGAQN
CCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
KSLKGKKFSESKDLMDEIRDLKKIVKDIGKSEKSYADENSSLVKFFKDLDLEEEFIEEII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
KKVGNLEENLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
HHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHEEC
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSIKDMEKAIIDLDYCDVILVDTTGR
CCCCCEEEEECEECCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCCEEEEECCCC
SSKNMMQISELRAFIEKIKEKSVHLVISASTKNKDIETIVKGYSILEYENIIITKLDETS
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCHHEEECCEEEEECCCHH
IYGSILTILDKGKNPISFITTGQDVPDDIKEGNKEEIAKIVLGENKLC
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKIRKGGFLGLFSKKSLEVTAAIDNYSTE
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCEEEEECCCCEEEEEEECCCCCC
KKYNSNTVNKINKGNNIEVIKRMLEERNNNVKYDNNINHDTNALDRYKEILESKSEGAQN
CCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
KSLKGKKFSESKDLMDEIRDLKKIVKDIGKSEKSYADENSSLVKFFKDLDLEEEFIEEII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
KKVGNLEENLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
HHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHEEC
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSIKDMEKAIIDLDYCDVILVDTTGR
CCCCCEEEEECEECCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCCEEEEECCCC
SSKNMMQISELRAFIEKIKEKSVHLVISASTKNKDIETIVKGYSILEYENIIITKLDETS
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCHHEEECCEEEEECCCHH
IYGSILTILDKGKNPISFITTGQDVPDDIKEGNKEEIAKIVLGENKLC
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447978; 9384377 [H]