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The map label for this gene is nsr [H]

Identifier: 148379516

GI number: 148379516

Start: 1682460

End: 1683155

Strand: Direct

Name: nsr [H]

Synonym: CBO1548

Alternate gene names: 148379516

Gene position: 1682460-1683155 (Clockwise)

Preceding gene: 148379514

Following gene: 148379519

Centisome position: 43.29

GC content: 25.0

Gene sequence:

>696_bases
ATGATAAGAATTAATGATTTAAAAGAAAGAGAGAAATATATTTTAAAGTATAGAATTAATGATATGTTTACTAAAGATAT
GAATCCTTTTATAGAACTTTTCTTTTTCAAAAAAAATGAGCATATTTGTAGAGAAGATGAAGAACTTAATTATCTTTTTT
TTCTTGTGAAAGGAAAAGCTAAAGTATATACAACTCTTAGCAATGGCAAGTCTTTGTTACTTTGCTTTTATGATGATTTT
AAATTATTGGGCGATGTAGAAATTATTAATTTAGAAAATGCATCTTCAAATGTGCAGGTTATAGAGGATACATATTGCCT
AGCTATATCCTTAAAAAATGTAAGATTGTATTTGCTTAATGATGCTAAATTTTTAAGGTTTATTTGTAGTTCTTTAGGTG
GAAAATTGAATAGATGTTCAAAAAACAGTTCTATAAATTTACTTTATCCTTTAGAAAATAGATTAGCCAGTTATATTCTT
GCTACTGGTGAAAGAGTAAATAATAATGAAGAAAGAATAATAAAGTTTAATGAAAACTTAACTGAAATAGGAGAGCTTCT
AGGTACAAGTTATAGACATTTATTAAGAACATTAAATAATCTTAGTTGTAAGGGAGCTATAAGAAAGAAAAGCAATTACT
TTCAAGTATTAGATGAGAAAATTCTAAAAAAGCTTGCAGCAGATCTATATAAATAA

Upstream 100 bases:

>100_bases
AGAAAAATTAAAATATTAAACTTAATTTATCATGAAAAAGTTGTAAAGGGATATGACATATGTCATACTTAAAACAGAAA
TTTACAAGGGGTTTAAAGTT

Downstream 100 bases:

>100_bases
TTATTTTGAAAAAATATTTTAAATAATTGTATTAAAAATCAACCTTTAAAATCAACCGAAAGGTTGATTTTTTTATGAGA
AATTTTCGTATCATAAAAAT

Product: cyclic nucleotide-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MIRINDLKEREKYILKYRINDMFTKDMNPFIELFFFKKNEHICREDEELNYLFFLVKGKAKVYTTLSNGKSLLLCFYDDF
KLLGDVEIINLENASSNVQVIEDTYCLAISLKNVRLYLLNDAKFLRFICSSLGGKLNRCSKNSSINLLYPLENRLASYIL
ATGERVNNNEERIIKFNENLTEIGELLGTSYRHLLRTLNNLSCKGAIRKKSNYFQVLDEKILKKLAADLYK

Sequences:

>Translated_231_residues
MIRINDLKEREKYILKYRINDMFTKDMNPFIELFFFKKNEHICREDEELNYLFFLVKGKAKVYTTLSNGKSLLLCFYDDF
KLLGDVEIINLENASSNVQVIEDTYCLAISLKNVRLYLLNDAKFLRFICSSLGGKLNRCSKNSSINLLYPLENRLASYIL
ATGERVNNNEERIIKFNENLTEIGELLGTSYRHLLRTLNNLSCKGAIRKKSNYFQVLDEKILKKLAADLYK
>Mature_231_residues
MIRINDLKEREKYILKYRINDMFTKDMNPFIELFFFKKNEHICREDEELNYLFFLVKGKAKVYTTLSNGKSLLLCFYDDF
KLLGDVEIINLENASSNVQVIEDTYCLAISLKNVRLYLLNDAKFLRFICSSLGGKLNRCSKNSSINLLYPLENRLASYIL
ATGERVNNNEERIIKFNENLTEIGELLGTSYRHLLRTLNNLSCKGAIRKKSNYFQVLDEKILKKLAADLYK

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=209, Percent_Identity=33.9712918660287, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 27018; Mature: 27018

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRINDLKEREKYILKYRINDMFTKDMNPFIELFFFKKNEHICREDEELNYLFFLVKGKA
CEECCCHHHHHHEEEEEEHHHHHHCCCCHHEEEEEEECCCCCCCCCCCCEEEEEEEECCE
KVYTTLSNGKSLLLCFYDDFKLLGDVEIINLENASSNVQVIEDTYCLAISLKNVRLYLLN
EEEEEECCCCEEEEEEECCCEECCCEEEEEECCCCCCCEEEECEEEEEEEEECEEEEEEC
DAKFLRFICSSLGGKLNRCSKNSSINLLYPLENRLASYILATGERVNNNEERIIKFNENL
CHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCH
TEIGELLGTSYRHLLRTLNNLSCKGAIRKKSNYFQVLDEKILKKLAADLYK
HHHHHHHCHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRINDLKEREKYILKYRINDMFTKDMNPFIELFFFKKNEHICREDEELNYLFFLVKGKA
CEECCCHHHHHHEEEEEEHHHHHHCCCCHHEEEEEEECCCCCCCCCCCCEEEEEEEECCE
KVYTTLSNGKSLLLCFYDDFKLLGDVEIINLENASSNVQVIEDTYCLAISLKNVRLYLLN
EEEEEECCCCEEEEEEECCCEECCCEEEEEECCCCCCCEEEECEEEEEEEEECEEEEEEC
DAKFLRFICSSLGGKLNRCSKNSSINLLYPLENRLASYILATGERVNNNEERIIKFNENL
CHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCH
TEIGELLGTSYRHLLRTLNNLSCKGAIRKKSNYFQVLDEKILKKLAADLYK
HHHHHHHCHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]