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The map label for this gene is copA [H]

Identifier: 148379284

GI number: 148379284

Start: 1419463

End: 1421898

Strand: Direct

Name: copA [H]

Synonym: CBO1304

Alternate gene names: 148379284

Gene position: 1419463-1421898 (Clockwise)

Preceding gene: 148379283

Following gene: 148379285

Centisome position: 36.52

GC content: 31.77

Gene sequence:

>2436_bases
ATGAAGAAATTATCATTTAATATAGAAGGAATGACTTGTGCAGCTTGTGCTAAAGCTGTGGAGAGGGTTTCTAAAAAATT
AGAAGGTGTTCAAGAGGCTAATGTGAACATAGCTACAGAAAAGTTAAGTATAATTTTTGATGAAAAAAAATGTAATACTT
TAGATATAGAAAAAGCCATAGAAAAAGCAGGATACAAAGCTTTTTTAGATGGGCAGCATATGAATTTAAAGATAGAAGGA
ATGACTTGTGCAGCTTGTGCCAAAGCTGTAGAAAGAGTTTCAAGAAAGTTAGAGGGTGTTATAGAAGCCAATGTTAATAT
AGCAACAGAAAAGCTTGATATAACTTTTGATAAATCAAAAGTAAGTATAAATGATATAAAAAGAGCTATAGAAAAGGCAG
GATATAAGGCTTTAGAAGAAAAAAATATAGAAGAAGAGAAAAAGGGAAAAGAAGATGCAATAAAATCTTTGTGGAGAAGA
TTTATAACTTCTTTAATATTTGCAGTACCTTTGCTTACTATATCTATGGGAAGTATGATGGGATTAAAGTTACCTAAAAT
TATTGATCCAATGCATAGCCCTTTAAATTTTGGATTAATACAACTTATTTTAGTAATTCCAATTATATTGGTAGGAAACA
AGTTCTTTAGGGTAGGGTTTAAATCTTTAGTTAAAGGAAGCCCTAATATGGACTCTTTAATTTCTATTGGTACATCAGCA
GCTGTAGTATATGGTATTTTCGCTATATTCCAAATATCTAAAGGAAATATGCATTATGCTCATGACTTGTATTTTGAATC
TGGAGCTACTATTTTAACCTTAATAACTTTAGGAAAATATTTAGAATCCGTATCTAAAGGTAAAACTTCTGAAGCTATAA
AAAAATTGATGGCCTTAGCTCCTAAAAATGCAACTATAATAAGAGACAATAAGGAAATAATAATTCCTATAGAAGAAGTT
AAAATAAATGATATAGTTTTAGTTAAACCAGGAGAAAAGCTTCCTGTGGATGGGGAAATTATTGAAGGTTCTACAGCTAT
AGATGAATCTATGCTTACAGGAGAAAGTTTACCTGTAGAAAAACATATAGGAGATATAGCAGTAGCAGGAAGCATAAATA
AGCATGGATTAATAAAATATAAAGCTACTAAAGTTGGGAAAGATACTACTTTAGCACAAATTATAAAACTTGTAGAAGAG
GCTCAGGGTAGTAAAGCTCCTATTGCAAGGCTAGCAGATAAAATTTCCGCTTATTTTGTACCAACAGTAATAGCTTTAGC
TATAATTTCTTCTTTAGCTTGGTATGTTAGTGGAAAATCTTTAATATTTTCATTAACTATATTTATTTCTGTATTGGTAA
TAGCTTGTCCGTGTGCTTTAGGATTAGCAACACCAACAGCTATTATGGTAGGCACAGGAAAAGGAGCAGAAAATGGGGTT
CTTATAAAAAGTGGAGGAGCTTTAGAAACTGCTCATAAAGTTCAGAGTATTATATTCGATAAAACAGGAACTATTACAGA
AGGAAAACCAAAAGTAACAGATATTTTGGTTTCCGAAGGAGTAGATGAAAAATATTTACTTCAAGTAGCAGCTACTGCAG
AAAAGGGTTCAGAACATCCATTAGGTGAAGCTATAGTAAAAAAAGCAGAAGAAGAAAATTTAGAATTATTTCAAGGTAAA
AATTTTAGAGCAATACCTGGTAAAGGCATAGAGGTTATTATAGGGGATAAAAAAGTGCTTCTTGGAAATTTAAGACTTAT
GGAAGAATATGAGGTAGAAATAAAGGATTTTATGGATAAATCTCATAAACTTTCAAAGGAAGGTAAGACCCCAATGTTTA
TAGCCATAGAAAATAAAATTAAAGGAATAATAGCTGTAGCAGACACTCTTAAGGAAAATAGTAAAAAAGCTATAGAGAAG
CTTCATGATATGGGTGTGGAAGTAGTTATGATAACTGGAGATAACAAAAATACCGCAGAGGCTATAGGAAAACAAGTAGG
TATAGATAAGATTTTTGCAGAAGTTCTTCCTAGTGATAAGGCTAACTGGGTAAAAAAACTTCAGCAAGAAGGAAAAATTG
TAGCTATGGTAGGAGATGGAATTAATGATGCTCCAGCGTTAGCTCAAGCAGATATTGGTATAGCCATAGGATCTGGAACA
GATGTAGCTATAGAATCTGCAGATATTGTGCTTATAAAAAGTGATTTAATGGATGTACCAACAGCTCTTAAGTTAAGTAG
AGCTACTATAAAAAATATTAAAGAAAACCTATTTTGGGCTTTTGGGTACAATACTTTGGGGATTCCAGTAGCTATGGGTG
TTTTATATATTTTTGGAGGACCGCTTTTAAATCCAATGATTGCAGCAGCGGCTATGAGTTTTAGTTCAGTTTCAGTACTT
TTAAATGCCTTAAGATTAAGAAGATTTAAATCTTAA

Upstream 100 bases:

>100_bases
TGATAATGGAGAAGAAAAGGTAGATGAAATTATAGATACATTAACTAAGTTGCTTGGTAAATAATAAATTTTAAATATCA
ATTCAAAGGTGGTGTAAAAA

Downstream 100 bases:

>100_bases
TATAAGTAAAATATAATAGTGATTACTTTTAATTTATTTGAGAAAGTTTAAAACTCAAATAGGCCTAAGTAAACAAAATT
ATATAAAATAAATTTTATTA

Product: copper-translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MKKLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAIEKAGYKAFLDGQHMNLKIEG
MTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSKVSINDIKRAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRR
FITSLIFAVPLLTISMGSMMGLKLPKIIDPMHSPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALAPKNATIIRDNKEIIIPIEEV
KINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVEKHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEE
AQGSKAPIARLADKISAYFVPTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHPLGEAIVKKAEEENLELFQGK
NFRAIPGKGIEVIIGDKKVLLGNLRLMEEYEVEIKDFMDKSHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKAIEK
LHDMGVEVVMITGDNKNTAEAIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIVAMVGDGINDAPALAQADIGIAIGSGT
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGGPLLNPMIAAAAMSFSSVSVL
LNALRLRRFKS

Sequences:

>Translated_811_residues
MKKLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAIEKAGYKAFLDGQHMNLKIEG
MTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSKVSINDIKRAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRR
FITSLIFAVPLLTISMGSMMGLKLPKIIDPMHSPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALAPKNATIIRDNKEIIIPIEEV
KINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVEKHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEE
AQGSKAPIARLADKISAYFVPTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHPLGEAIVKKAEEENLELFQGK
NFRAIPGKGIEVIIGDKKVLLGNLRLMEEYEVEIKDFMDKSHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKAIEK
LHDMGVEVVMITGDNKNTAEAIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIVAMVGDGINDAPALAQADIGIAIGSGT
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGGPLLNPMIAAAAMSFSSVSVL
LNALRLRRFKS
>Mature_811_residues
MKKLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAIEKAGYKAFLDGQHMNLKIEG
MTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSKVSINDIKRAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRR
FITSLIFAVPLLTISMGSMMGLKLPKIIDPMHSPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALAPKNATIIRDNKEIIIPIEEV
KINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVEKHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEE
AQGSKAPIARLADKISAYFVPTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHPLGEAIVKKAEEENLELFQGK
NFRAIPGKGIEVIIGDKKVLLGNLRLMEEYEVEIKDFMDKSHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKAIEK
LHDMGVEVVMITGDNKNTAEAIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIVAMVGDGINDAPALAQADIGIAIGSGT
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGGPLLNPMIAAAAMSFSSVSVL
LNALRLRRFKS

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=863, Percent_Identity=40.4403244495944, Blast_Score=575, Evalue=1e-164,
Organism=Homo sapiens, GI115529486, Length=903, Percent_Identity=37.6522702104097, Blast_Score=546, Evalue=1e-155,
Organism=Homo sapiens, GI55743073, Length=543, Percent_Identity=45.48802946593, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI28373107, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI28373105, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI28373115, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373111, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373113, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373103, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI28373109, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI10835220, Length=216, Percent_Identity=31.4814814814815, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI27886529, Length=216, Percent_Identity=31.4814814814815, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI310128958, Length=210, Percent_Identity=31.9047619047619, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI4502285, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI24638454, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI209413709, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI118498343, Length=172, Percent_Identity=35.4651162790698, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI48762685, Length=190, Percent_Identity=30.5263157894737, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI48762691, Length=190, Percent_Identity=30.5263157894737, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI48762689, Length=190, Percent_Identity=30.5263157894737, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI48762687, Length=190, Percent_Identity=30.5263157894737, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI153946397, Length=240, Percent_Identity=27.5, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI51944966, Length=361, Percent_Identity=22.9916897506925, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI22748667, Length=379, Percent_Identity=24.2744063324538, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4502271, Length=375, Percent_Identity=24, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI237681111, Length=346, Percent_Identity=22.8323699421965, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI237681109, Length=346, Percent_Identity=22.8323699421965, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI21361181, Length=346, Percent_Identity=22.8323699421965, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI297374799, Length=344, Percent_Identity=23.546511627907, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI83700225, Length=344, Percent_Identity=23.546511627907, Blast_Score=81, Evalue=5e-15,
Organism=Escherichia coli, GI1786691, Length=850, Percent_Identity=38.9411764705882, Blast_Score=566, Evalue=1e-162,
Organism=Escherichia coli, GI1789879, Length=751, Percent_Identity=33.422103861518, Blast_Score=348, Evalue=7e-97,
Organism=Escherichia coli, GI1786914, Length=452, Percent_Identity=34.5132743362832, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI2367363, Length=602, Percent_Identity=22.7574750830565, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17556548, Length=880, Percent_Identity=37.0454545454545, Blast_Score=482, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17554158, Length=227, Percent_Identity=32.15859030837, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988506, Length=227, Percent_Identity=32.15859030837, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193210130, Length=227, Percent_Identity=32.15859030837, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566766, Length=215, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17557770, Length=215, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17557486, Length=215, Percent_Identity=28.3720930232558, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71997262, Length=190, Percent_Identity=32.1052631578947, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71997275, Length=190, Percent_Identity=32.1052631578947, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193203356, Length=225, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193203354, Length=225, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71997269, Length=172, Percent_Identity=34.8837209302326, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17541776, Length=204, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559224, Length=324, Percent_Identity=23.4567901234568, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=119, Percent_Identity=37.8151260504202, Blast_Score=80, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320475, Length=869, Percent_Identity=34.0621403912543, Blast_Score=435, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6319772, Length=673, Percent_Identity=28.5289747399703, Blast_Score=290, Evalue=6e-79,
Organism=Saccharomyces cerevisiae, GI6321430, Length=527, Percent_Identity=26.5654648956357, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6325221, Length=528, Percent_Identity=27.2727272727273, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321271, Length=650, Percent_Identity=24.9230769230769, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321432, Length=169, Percent_Identity=31.3609467455621, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320245, Length=317, Percent_Identity=24.6056782334385, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320244, Length=311, Percent_Identity=24.4372990353698, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320243, Length=311, Percent_Identity=24.4372990353698, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221329854, Length=639, Percent_Identity=34.8982785602504, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI17136664, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762455, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762453, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762447, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762457, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762449, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762445, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762451, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24668704, Length=192, Percent_Identity=31.7708333333333, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24668708, Length=192, Percent_Identity=31.7708333333333, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281366617, Length=192, Percent_Identity=31.7708333333333, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24668696, Length=203, Percent_Identity=31.5270935960591, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI161085803, Length=203, Percent_Identity=31.5270935960591, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281366676, Length=248, Percent_Identity=25.8064516129032, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281362164, Length=268, Percent_Identity=25, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553437, Length=268, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553435, Length=270, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45553439, Length=270, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648576, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553441, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648580, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648578, Length=268, Percent_Identity=24.6268656716418, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648582, Length=227, Percent_Identity=25.9911894273128, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 87549; Mature: 87549

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00154 ATPASE_E1_E2 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAI
CCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCCEECHHHHH
EKAGYKAFLDGQHMNLKIEGMTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSK
HHCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCC
VSINDIKRAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRRFITSLIFAVPLLTISMGSMM
CCHHHHHHHHHHHCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKLPKIIDPMHSPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCCCHH
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALA
HHHHHHHHHHEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PKNATIIRDNKEIIIPIEEVKINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVE
CCCCEEEECCCEEEEEEHEEEECCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCCCCHH
KHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEEAQGSKAPIARLADKISAYFV
HHCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCE
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHP
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
LGEAIVKKAEEENLELFQGKNFRAIPGKGIEVIIGDKKVLLGNLRLMEEYEVEIKDFMDK
HHHHHHHHHCCCCCHHHCCCCEEECCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHH
SHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKAIEKLHDMGVEVVMITGDNKNTAE
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
AIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIVAMVGDGINDAPALAQADIGIAIGSGT
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCEEEECCCC
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGG
CEEEECCCEEEEECCHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCC
PLLNPMIAAAAMSFSSVSVLLNALRLRRFKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLSFNIEGMTCAACAKAVERVSKKLEGVQEANVNIATEKLSIIFDEKKCNTLDIEKAI
CCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEEECCCCCEECHHHHH
EKAGYKAFLDGQHMNLKIEGMTCAACAKAVERVSRKLEGVIEANVNIATEKLDITFDKSK
HHCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCC
VSINDIKRAIEKAGYKALEEKNIEEEKKGKEDAIKSLWRRFITSLIFAVPLLTISMGSMM
CCHHHHHHHHHHHCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKLPKIIDPMHSPLNFGLIQLILVIPIILVGNKFFRVGFKSLVKGSPNMDSLISIGTSA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCCCHH
AVVYGIFAIFQISKGNMHYAHDLYFESGATILTLITLGKYLESVSKGKTSEAIKKLMALA
HHHHHHHHHHEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
PKNATIIRDNKEIIIPIEEVKINDIVLVKPGEKLPVDGEIIEGSTAIDESMLTGESLPVE
CCCCEEEECCCEEEEEEHEEEECCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCCCCHH
KHIGDIAVAGSINKHGLIKYKATKVGKDTTLAQIIKLVEEAQGSKAPIARLADKISAYFV
HHCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PTVIALAIISSLAWYVSGKSLIFSLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCE
LIKSGGALETAHKVQSIIFDKTGTITEGKPKVTDILVSEGVDEKYLLQVAATAEKGSEHP
EEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
LGEAIVKKAEEENLELFQGKNFRAIPGKGIEVIIGDKKVLLGNLRLMEEYEVEIKDFMDK
HHHHHHHHHCCCCCHHHCCCCEEECCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHH
SHKLSKEGKTPMFIAIENKIKGIIAVADTLKENSKKAIEKLHDMGVEVVMITGDNKNTAE
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
AIGKQVGIDKIFAEVLPSDKANWVKKLQQEGKIVAMVGDGINDAPALAQADIGIAIGSGT
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCEEEECCCC
DVAIESADIVLIKSDLMDVPTALKLSRATIKNIKENLFWAFGYNTLGIPVAMGVLYIFGG
CEEEECCCEEEEECCHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCC
PLLNPMIAAAAMSFSSVSVLLNALRLRRFKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA