Click here to switch to the map view.

The map label for this gene is xdhC2 [H]

Identifier: 148379268

GI number: 148379268

Start: 1399427

End: 1399900

Strand: Direct

Name: xdhC2 [H]

Synonym: CBO1287

Alternate gene names: 148379268

Gene position: 1399427-1399900 (Clockwise)

Preceding gene: 148379267

Following gene: 148379269

Centisome position: 36.0

GC content: 30.17

Gene sequence:

>474_bases
ATGAGTTTAAAAAGAAAAATAAAACTTACAGTTAATGATAAAAAGTATGAAATAGAAATAGATATTAGAGAATCTTTATC
AGAAGTATTAAGAAGTAGATTACATTTAACAGGTGTTAAACAAGGATGTCTTGTAGGAGAATGTGGAGCATGTACTGTCT
TAATAGATGGTGTCCCAACAGACTCATGTATTTACTTAGCGGCTTGGGCTGATGGTAAAACAATAAAAACTATTGAGGGA
GTACAAAAAAATGGTGAGCTTTCAGAGGTTCAAAAAGCCTTTATAGATGAAGGTGCTGTACAATGTGGATTCTGTACACC
GGGTTTAGTTTTAACTACAACAGCTTTAGTAGAAAGCGAAAAAAACTATACTGATGATGAAATAAAAAGAGAAATATCAG
GTCATTTATGTAGATGTACTGGATATAATAAAATATTTAATGCTACCAAAAAAGCTATTTTAAAAAGAAAATAA

Upstream 100 bases:

>100_bases
CAAGAATTAACTTATAGAGGACTTAAAGAATCTGCTAAAAGAGCAGAAAGTCTTGAAAATATAAAGTAATAGGATACAGT
TAGGGGGATGATGAATATAT

Downstream 100 bases:

>100_bases
TATTTAGGTTTATAATATGATAATCACTACAAGGTAAGTTTTGACAAGATTATTTTTAAAGTATAATATTAAGATATATA
GTTTAATTATTAAATGATTT

Product: xanthine dehydrogenase family protein, iron-sulfur binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSLKRKIKLTVNDKKYEIEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEG
VQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK

Sequences:

>Translated_157_residues
MSLKRKIKLTVNDKKYEIEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEG
VQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
>Mature_156_residues
SLKRKIKLTVNDKKYEIEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEGV
QKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=162, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=32.484076433121, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=55.2447552447552, Blast_Score=162, Evalue=9e-42,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=37.6543209876543, Blast_Score=117, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=152, Percent_Identity=38.8157894736842, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.012987012987, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=34.2105263157895, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=33.125, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=33.125, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=34.2105263157895, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=34.1935483870968, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 17329; Mature: 17198

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKRKIKLTVNDKKYEIEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPT
CCCCEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DSCIYLAAWADGKTIKTIEGVQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESE
CCEEEEEEECCCCEEHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
KNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
CCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLKRKIKLTVNDKKYEIEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPT
CCCEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DSCIYLAAWADGKTIKTIEGVQKNGELSEVQKAFIDEGAVQCGFCTPGLVLTTTALVESE
CCEEEEEEECCCCEEHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
KNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
CCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]