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The map label for this gene is patH [H]

Identifier: 148379166

GI number: 148379166

Start: 1295099

End: 1295923

Strand: Direct

Name: patH [H]

Synonym: CBO1181

Alternate gene names: 148379166

Gene position: 1295099-1295923 (Clockwise)

Preceding gene: 148379165

Following gene: 148379167

Centisome position: 33.32

GC content: 26.91

Gene sequence:

>825_bases
TTGAATATAAAAAAGTTTAAAAAAATATTTTTAAGTATGTCATTAGTTGTAGCCTTAGGAGTAGCATTAACAGCATGTGC
TCAGAAGAATAAAGAAATAAAGGAAAATAAAAATACAATAAAAATAGGAACTTCAGGACAGTACTATCCTTTTACTTTTA
TAGATAAAGATAGTAATAAAGTCCAAGGATTTGAAATAGATATTTGGGAAGAAATAGGTAAAAGAACAGGTTATAAACCA
GAATTTAAGGTAGCAGATTGGACAGGCATTATGGGAATGCTAGATACAGGTAAAATAGATACTGTAGCCAATGAGATAAC
TGTAACAGATAAGAAAAAAGAAAAATATTATTTTTCAAAACCTTATGTTTATTCAGGAGTACAGTTAGCTACTAAAAAAG
GAAATAATAATATAAAATCTTTAAAGGATTTAGAGGGAAAAAGTGTAGCTACGCAGGTAGGAACTAATTATTCTCAATCC
ATAGAAGATCATAATAATAAGAATAAAGGAGAAGATATAAAAACAAAACAATATAATAGTTTTTCAGGTATGTTCCAAGA
TGTGGATTTAGGTAGAGTTGATGCTTTAATAGAAGACAAATTAGCCTGTCTTGTAAATATAAAAAAATCAGGATTAAATT
TACAGTTAGCCGGTGAACCTATAGAAGAGATGGAAAATGCATATCCTTTTGTAAAGAAGGATGAAAATAAAGAAAAAATA
GAAAAAATAAATAAAGCTTTAGATGATATGAAAAATGATGGAACTTTACAAAATATATCTAAAAAATGGTTTGGAGAAAA
TGTTACAGAAAAGAGTAAAAAATAA

Upstream 100 bases:

>100_bases
GTAATGGTAGAGTTATTTAATTTTATGCAAAAATTATTAGAAAGAAAAATAGGAAAAGCTTATTAAAATTTAATATTAAT
AGTATTAGGAGGATATAGAA

Downstream 100 bases:

>100_bases
TCTATTTGATTAAATTTAAATATTTTTAATATAAAATTTTAAAGATATTAATATAAAATCCATAGTTACAAATAATAAAA
TAAAAAACAGTGGTGATTAT

Product: polar amino acid ABC transporter amino acid-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNIKKFKKIFLSMSLVVALGVALTACAQKNKEIKENKNTIKIGTSGQYYPFTFIDKDSNKVQGFEIDIWEEIGKRTGYKP
EFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSKPYVYSGVQLATKKGNNNIKSLKDLEGKSVATQVGTNYSQS
IEDHNNKNKGEDIKTKQYNSFSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK

Sequences:

>Translated_274_residues
MNIKKFKKIFLSMSLVVALGVALTACAQKNKEIKENKNTIKIGTSGQYYPFTFIDKDSNKVQGFEIDIWEEIGKRTGYKP
EFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSKPYVYSGVQLATKKGNNNIKSLKDLEGKSVATQVGTNYSQS
IEDHNNKNKGEDIKTKQYNSFSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK
>Mature_274_residues
MNIKKFKKIFLSMSLVVALGVALTACAQKNKEIKENKNTIKIGTSGQYYPFTFIDKDSNKVQGFEIDIWEEIGKRTGYKP
EFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSKPYVYSGVQLATKKGNNNIKSLKDLEGKSVATQVGTNYSQS
IEDHNNKNKGEDIKTKQYNSFSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK

Specific function: Probably part of a binding-protein-dependent transport system for an amino acid [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=260, Percent_Identity=35.7692307692308, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1787031, Length=260, Percent_Identity=31.1538461538462, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788649, Length=267, Percent_Identity=27.3408239700375, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787085, Length=230, Percent_Identity=27.8260869565217, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787088, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788648, Length=236, Percent_Identity=25.4237288135593, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 30977; Mature: 30977

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01034 GLYCOSYL_HYDROL_F16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKKFKKIFLSMSLVVALGVALTACAQKNKEIKENKNTIKIGTSGQYYPFTFIDKDSNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCCCEEEEEEEECCCCC
VQGFEIDIWEEIGKRTGYKPEFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSK
CCCEEEHHHHHHHHHCCCCCCEEECCHHHHHHCCCCCCHHHHHCEEEECCCCCCCEEECC
PYVYSGVQLATKKGNNNIKSLKDLEGKSVATQVGTNYSQSIEDHNNKNKGEDIKTKQYNS
CEEECCEEEEEECCCCCHHHHHHCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCC
FSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
HHCCHHCCCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCHHHHHHCCCCCCCCCCHHHH
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK
HHHHHHHHHHCCCCCHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MNIKKFKKIFLSMSLVVALGVALTACAQKNKEIKENKNTIKIGTSGQYYPFTFIDKDSNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCCCEEEEEEEECCCCC
VQGFEIDIWEEIGKRTGYKPEFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSK
CCCEEEHHHHHHHHHCCCCCCEEECCHHHHHHCCCCCCHHHHHCEEEECCCCCCCEEECC
PYVYSGVQLATKKGNNNIKSLKDLEGKSVATQVGTNYSQSIEDHNNKNKGEDIKTKQYNS
CEEECCEEEEEECCCCCHHHHHHCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCC
FSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
HHCCHHCCCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCHHHHHHCCCCCCCCCCHHHH
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK
HHHHHHHHHHCCCCCHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA