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The map label for this gene is gufA [H]

Identifier: 148379162

GI number: 148379162

Start: 1291175

End: 1291984

Strand: Direct

Name: gufA [H]

Synonym: CBO1177

Alternate gene names: 148379162

Gene position: 1291175-1291984 (Clockwise)

Preceding gene: 148379161

Following gene: 148379163

Centisome position: 33.22

GC content: 37.28

Gene sequence:

>810_bases
ATGACTTGGTTTAAAGAATTGAATCCTATTATGCAGGCTCTTTTAGCTACATTATTTACCTGGGCAGTTACAGCTTTAGG
AGCATCATTAGTGTTTTTCTTTAAAAATATAAATAAAAAAGTATTAAATGCTATGTTAGGTTTTGCAGCAGGAGTAATGA
TTGCGGCTAGCTATTGGTCACTTTTAGCACCGGCTATAGAAATGGCAGAATCCCAGGGCAAAATTGCATGGATACCGGCA
GCAGTAGGTTTTCTAGCAGGAGGAATATTTTTAAGAATAGTAGATAGAATTCTTCCACACCTTCATTTAGGTAAAGATAG
AGATGAGGCGGAGGGAATTAAAACTAGTTGGCAAAAGAGCATATTATTAGTTTTAGCTATAACCCTTCATAACATACCAG
AAGGATTAGCTGTAGGGGTGGCCTTTGGAGCAGTAGGGGCCAATATAGAGTCTGCATCTTTAGCAGGAGCTATAGCTTTA
GCATTAGGTATAGGAATTCAAAACTTTCCTGAAGGAGCAGCAGTATCTATACCACTAAGAAGAGAAGGAAATAGTAGATT
AAAAAGTTTTTGGTATGGGCAAGCTTCTGGTATAGTTGAACCTATAGCAGGTGTTATAGGGGCAGCGGCAGTATTATTTA
TAAGAAATTTATTACCCTATGCCTTATCCTTTGCAGCTGGAGCCATGATATTTGTTGTAGTAGAGGAACTAATTCCTGAA
GCCCAGGAAGGAAAGGATACAGATATATCATCTATAGGAGTATTAATTGGATTTACTGTAATGATGATATTAGATGTAGC
TTTAGGCTAA

Upstream 100 bases:

>100_bases
TAAATATTGATTATATTAGTAGTACGTGATAAAATCAAAATAAGGAATTATCAAGTAATAATTATTATCGTTTATTTAGA
ACTAGAAAGAAGGGGATAGT

Downstream 100 bases:

>100_bases
ACAGAGTTCTTGGCTTCAGAGGGAGTTTTTACTCACTCTGAAGCTTATTAACAGAATTCTTAGGAGTTTTACTCCTTAGA
AGTTGTTATCCTTTAGGGGA

Product: zinc transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTWFKELNPIMQALLATLFTWAVTALGASLVFFFKNINKKVLNAMLGFAAGVMIAASYWSLLAPAIEMAESQGKIAWIPA
AVGFLAGGIFLRIVDRILPHLHLGKDRDEAEGIKTSWQKSILLVLAITLHNIPEGLAVGVAFGAVGANIESASLAGAIAL
ALGIGIQNFPEGAAVSIPLRREGNSRLKSFWYGQASGIVEPIAGVIGAAAVLFIRNLLPYALSFAAGAMIFVVVEELIPE
AQEGKDTDISSIGVLIGFTVMMILDVALG

Sequences:

>Translated_269_residues
MTWFKELNPIMQALLATLFTWAVTALGASLVFFFKNINKKVLNAMLGFAAGVMIAASYWSLLAPAIEMAESQGKIAWIPA
AVGFLAGGIFLRIVDRILPHLHLGKDRDEAEGIKTSWQKSILLVLAITLHNIPEGLAVGVAFGAVGANIESASLAGAIAL
ALGIGIQNFPEGAAVSIPLRREGNSRLKSFWYGQASGIVEPIAGVIGAAAVLFIRNLLPYALSFAAGAMIFVVVEELIPE
AQEGKDTDISSIGVLIGFTVMMILDVALG
>Mature_268_residues
TWFKELNPIMQALLATLFTWAVTALGASLVFFFKNINKKVLNAMLGFAAGVMIAASYWSLLAPAIEMAESQGKIAWIPAA
VGFLAGGIFLRIVDRILPHLHLGKDRDEAEGIKTSWQKSILLVLAITLHNIPEGLAVGVAFGAVGANIESASLAGAIALA
LGIGIQNFPEGAAVSIPLRREGNSRLKSFWYGQASGIVEPIAGVIGAAAVLFIRNLLPYALSFAAGAMIFVVVEELIPEA
QEGKDTDISSIGVLIGFTVMMILDVALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=329, Percent_Identity=42.2492401215805, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI229577422, Length=335, Percent_Identity=39.1044776119403, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1789419, Length=259, Percent_Identity=30.1158301158301, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17507805, Length=320, Percent_Identity=48.125, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24652846, Length=164, Percent_Identity=54.2682926829268, Blast_Score=175, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28389; Mature: 28258

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWFKELNPIMQALLATLFTWAVTALGASLVFFFKNINKKVLNAMLGFAAGVMIAASYWS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAPAIEMAESQGKIAWIPAAVGFLAGGIFLRIVDRILPHLHLGKDRDEAEGIKTSWQKS
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ILLVLAITLHNIPEGLAVGVAFGAVGANIESASLAGAIALALGIGIQNFPEGAAVSIPLR
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
REGNSRLKSFWYGQASGIVEPIAGVIGAAAVLFIRNLLPYALSFAAGAMIFVVVEELIPE
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AQEGKDTDISSIGVLIGFTVMMILDVALG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TWFKELNPIMQALLATLFTWAVTALGASLVFFFKNINKKVLNAMLGFAAGVMIAASYWS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAPAIEMAESQGKIAWIPAAVGFLAGGIFLRIVDRILPHLHLGKDRDEAEGIKTSWQKS
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ILLVLAITLHNIPEGLAVGVAFGAVGANIESASLAGAIALALGIGIQNFPEGAAVSIPLR
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
REGNSRLKSFWYGQASGIVEPIAGVIGAAAVLFIRNLLPYALSFAAGAMIFVVVEELIPE
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AQEGKDTDISSIGVLIGFTVMMILDVALG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]