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The map label for this gene is resE [H]

Identifier: 148379032

GI number: 148379032

Start: 1143046

End: 1144452

Strand: Direct

Name: resE [H]

Synonym: CBO1042

Alternate gene names: 148379032

Gene position: 1143046-1144452 (Clockwise)

Preceding gene: 148379031

Following gene: 148379035

Centisome position: 29.41

GC content: 28.36

Gene sequence:

>1407_bases
ATGAAAATGTCTTTAAAGAAAAAACTTTCTTTAGGATTTTTAATTGCGGTTATAGGTTCAATAATAATTGCTAGTTCCAT
ATCTAATTATATGATAAATAACAGATTCAATGAATATTTGGTTCAAGAACATAAAAATAAAATAAACCAAATTATAGTGG
CAATTGAAGATATGTATAAAGAGGATAAAGGCTTTCAAGCATTAAAGTATGATGAAATAAAAAGATATGCAGTTTTAAAT
GAACTTTATATAGAGATAAAAGATAAAAAGGGGAGCAAGATATTTACCTCTGGGGATGACCATCTTAAACATAGAAGTAT
GATGAATTCTATGATGGGGCATGGAATGGGTAATATGATGGGGAAAATGAAAAATTTAGATTTAGGGGATTATAAAGAAG
AAGAACAATGGCTTAAAAAGAACAATGTGACTTTTGGAAAGATAACTATTGGATATTTTGGTACTTCATATTTAAACAAT
GGAGCATTAACATTTAAAAGAACCTTAAATCATTCCTTTATTGTATCTATGGTCATAACCTTTATTTTAGGGCTTATACT
GAGCTGGATTTTATCAAAACAACTTTCAAAACCTTTGGTTAAAATAAAAGAAATAGCTAATACAATGAGAATGGGCAATT
TAAATATAAGGTCTAATATAAAAAGTAATACGACAGAAATTCAGGAATTATCAAATTCTATAAATTATTTAGCAGAAACA
CTACAACAACAGGAGGCTCTTCGTAAAAGATTGACTTCAGATATGGCTCATGAAATAAGAACTCCAATTACAACTTTAAA
AACTCATGTTGAGGCAATAATAGATGGCATATGGGAGCCTACAGAGGAAAGATTGCAGGTCTTTTATGAGGAATTAGAGC
GATTAACAAATCTTGTGAATAATTTAAGAAATATTTCTAAATTAGAAAAAGCCGAAACAGTTGTAAATAAAACTAACTTA
AATATTACAAAGGAAATAGAAAAAGTTGTAGAAACATTTAATCCTTTATATGAAAAAAGCGGTTTTAAAATAGTTACTAA
ACTGGAGAAGGATGTATATGGTTTTATAGATAAGGATAAATTAAAGCAAATTATGCATAATCTTTTATCTAATTCACATA
AATATTTAAATGAAGATGGATTAGTAAAGGTTTCATTATCAAAGGGAAAAGATAAAATATTTATAAAGGTTGAAGATAAT
GGAGAGGGTATTCCAGAGGAGGATTTACCTCATATATTTGAAAGATTTTATAGAAGTGATGTATCAAGGAATAAAACCAC
AGGAGGTACAGGTCTTGGTCTTACCATAACAAAAACTTTAGTAGAAGCTCATGGTGGGCATATTAGAGTAGAAAGTAAGA
TGGGAGTTGGAACCAAGTTTATTATAGAGATAAAAACTACTCTTTAG

Upstream 100 bases:

>100_bases
ATATAAAAAATATAAGACAAAAGATAGAAGATAATCCTAAAGCCCCTAACTATATTACTACTGTATATGGAGTTGGATAC
AGATTTGGAGGAAAAAATTA

Downstream 100 bases:

>100_bases
ATTTAAGTTTATTGTAAAAATATTTTTATTATTTTGTCCTATAATTTTATAAAGGTTTTATCTTTTTTGTTGCTTTGCTT
TTGTTTAAGCATGAATTTTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKRYAVLN
ELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNN
GALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSINYLAET
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVVNKTNL
NITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDN
GEGIPEEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL

Sequences:

>Translated_468_residues
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKRYAVLN
ELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNN
GALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSINYLAET
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVVNKTNL
NITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDN
GEGIPEEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
>Mature_468_residues
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKRYAVLN
ELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNN
GALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSINYLAET
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVVNKTNL
NITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDN
GEGIPEEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=29.3040293040293, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786783, Length=395, Percent_Identity=27.8481012658228, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=27.6119402985075, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=31.3304721030043, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789149, Length=344, Percent_Identity=27.6162790697674, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=24.8299319727891, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=25.8964143426295, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=22.3938223938224, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=22.742474916388, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=261, Percent_Identity=24.1379310344828, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788279, Length=279, Percent_Identity=25.8064516129032, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=288, Percent_Identity=25.3472222222222, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=27.5229357798165, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=305, Percent_Identity=24.2622950819672, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790436, Length=214, Percent_Identity=27.5700934579439, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=289, Percent_Identity=21.1072664359862, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=385, Percent_Identity=21.8181818181818, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=23.7068965517241, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53574; Mature: 53574

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKGFQALKYDEIKRYAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMM
HCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHH
GKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNNGALTFKRTLNHSFIVSMVIT
HHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEEHHHHHHCCCCEEEHHHHCHHHHHHHHHH
FILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSINYLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHH
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVN
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NLRNISKLEKAETVVNKTNLNITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCHHH
LKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDNGEGIPEEDLPHIFERFYRSD
HHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
VSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKGFQALKYDEIKRYAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMM
HCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHH
GKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLNNGALTFKRTLNHSFIVSMVIT
HHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEEHHHHHHCCCCEEEHHHHCHHHHHHHHHH
FILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNIRSNIKSNTTEIQELSNSINYLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHH
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVN
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NLRNISKLEKAETVVNKTNLNITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCHHH
LKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDNGEGIPEEDLPHIFERFYRSD
HHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
VSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]