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The map label for this gene is nsr [H]

Identifier: 148379014

GI number: 148379014

Start: 1125987

End: 1126676

Strand: Direct

Name: nsr [H]

Synonym: CBO1024

Alternate gene names: 148379014

Gene position: 1125987-1126676 (Clockwise)

Preceding gene: 148379012

Following gene: 148379016

Centisome position: 28.97

GC content: 24.78

Gene sequence:

>690_bases
ATGAAAAAAATTTTGAATAAAGAGCTTTTAAACAATTATATTGATAAGCATAATATAGAAAGCATATTTGACAAGGATAT
ATTAAAATATGCACAACTTCATTTTTATGAAAAAGAGGAATACATATTAAAAGCAGAGTCTAATCTTGAATACTATTATT
TGATTGTAGATGGGAAAATCAAAATTTCATATCCCTTTGAAAACGGTAAACCAATGCTTTTAAAGTTTTACAAAGACTTT
AATACTATAGGAGATTTAGAGTTTTTAAAAAACATTCCAATACTCTGCGACGTTGATGCAGTAGGAGATACTTATTTAAT
AGCAATACCTTCAGATATACTCAGAAAAAAGTATTTAGATAATGTAAAGTTTTTACACCATTTAATAGACTCTTTAAGTG
AAAAACTTTATGCAACAATTAATAATAGCTCATATAATTTTGTATATCCGCTCATAAATAGGTTATCTAGTTATCTAGTT
GAACATATAGAAGACAAAAACTATATAATTTTAAATTCATCATTCTTAGAAATTGCTCAATTCCTCGGAACAACCTATAG
GCATTTAAATAGAACCTTTAAAGAACTTGAATCAAAATCAATTATAAAATGTGAGAATAAAACAATATATATATTAGATG
AAAATAGACTTAGGGCCCTATCTAAAAACTTTTATATAAAATCCTTATAA

Upstream 100 bases:

>100_bases
TTATATAAATTACTCCTATGTTTAGTTTACAATAGGTTATAAATAAATTACAATAATTATATAAATTTTAATATGACATA
TGTCATGTTATGGAGGACTT

Downstream 100 bases:

>100_bases
TATTAGGATATTATAATTAATAAAATAGGACCTACCATAAAAAAGTAAGTCCTTGTTACGTCTCTTAAGAATATTGCTTT
TGTTCTAATATAGTAAATTT

Product: cyclic nucleotide-binding regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKILNKELLNNYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKPMLLKFYKDF
NTIGDLEFLKNIPILCDVDAVGDTYLIAIPSDILRKKYLDNVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYIILNSSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL

Sequences:

>Translated_229_residues
MKKILNKELLNNYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKPMLLKFYKDF
NTIGDLEFLKNIPILCDVDAVGDTYLIAIPSDILRKKYLDNVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYIILNSSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL
>Mature_229_residues
MKKILNKELLNNYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKIKISYPFENGKPMLLKFYKDF
NTIGDLEFLKNIPILCDVDAVGDTYLIAIPSDILRKKYLDNVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLV
EHIEDKNYIILNSSFLEIAQFLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=168, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 27189; Mature: 27189

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILNKELLNNYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKI
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECEE
KISYPFENGKPMLLKFYKDFNTIGDLEFLKNIPILCDVDAVGDTYLIAIPSDILRKKYLD
EEEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCEEEEEECHHHHHHHHHH
NVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLVEHIEDKNYIILNSSFLEIAQ
HHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
FLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECHHHHHHHHCEEEECC
>Mature Secondary Structure
MKKILNKELLNNYIDKHNIESIFDKDILKYAQLHFYEKEEYILKAESNLEYYYLIVDGKI
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECEE
KISYPFENGKPMLLKFYKDFNTIGDLEFLKNIPILCDVDAVGDTYLIAIPSDILRKKYLD
EEEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCEEEEEECHHHHHHHHHH
NVKFLHHLIDSLSEKLYATINNSSYNFVYPLINRLSSYLVEHIEDKNYIILNSSFLEIAQ
HHHHHHHHHHHHHHHEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
FLGTTYRHLNRTFKELESKSIIKCENKTIYILDENRLRALSKNFYIKSL
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]