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The map label for this gene is fabH [H]

Identifier: 148378718

GI number: 148378718

Start: 826921

End: 827919

Strand: Reverse

Name: fabH [H]

Synonym: CBO0718

Alternate gene names: 148378718

Gene position: 827919-826921 (Counterclockwise)

Preceding gene: 148378724

Following gene: 148378715

Centisome position: 21.3

GC content: 30.33

Gene sequence:

>999_bases
ATGAGTATAAAAATTAAAAACATCGAGTATTACCATCCTAAAACAAGCTATTCTAATGAATATTTTTTGAAACATTTTTC
AGAGCAAGACATAGATATTTCCGGATTATTAAATGTTACTGGAAGAAATAAGAGATATGTTTCTGAAGATTTTAATGAAA
ATTCTTTAACTATGGCTATAGAAGCTTGCAAAAAAGTAATAAGGACTGCAAATATAGATGTACAAGATATAAATTTAGTT
GTATTTGTATCTTCTACCCCAGAATATCTATCTCCTACAAATGCTGTTAAAGTTCATGATGCTTTAGGTTTATCTAAGAA
TACAAATGCATATGATATGAATGGTAATTGTGCGGGGATGATCATTGCAATGGATCAAGTCTGTAGAACAATGAAAAGCA
ATAATAGAATTAAATATAGCTTACTTGTAGGTTCAGACTTAGTAATTAGATATTCAAGAAAATCAGAACCTATTACTTAT
GCTAATTTTGGAGAATCTGCATGTGCTGTTTTACTAGAGAACACTGATGATAATATATCAGATTTCATAGATAGTTCATC
TTACGTAGATAGCTCATTAAGCTGCTATATAAAATTTCCTCCTGATGGCTTTTCTAAGGTATTACCAATAGATGAAGATA
CGCCAAAAGATAATAGAATAATAGAATGGATGGATTTTAATACAGATGAGGCATTTGCCAGTTCTGTTGATTCAATAAAT
GAAATACTAGATCGAAATAATCTAACTAAAGATGATGTTAAATTATATTGCTTATCTCAGTTTGCAAAGAAAAATATTGA
TATGATAAGAGAGATTTTAGAAGAACCAGATTACAAATTTCCATTCGTAGGTGACAGATTTGGATATACAGGTGTTACAA
GCCCATTTCTTGCCTTAGCCGATTCTGTTTCAAATGGTAACCTTAAGCCTGGAGATTATGTTATTTTATGGACTGTTGGA
GCTGGTGTGGTTGCTTCATGTATACTACTTAGATATTAA

Upstream 100 bases:

>100_bases
ATTTATTACGTCATTATAAATGTATTATCTTAATTTATTGAAATATTTTTCGATAGTTATAAATAGACATATTTAACGAT
AAAGATAAGGCGGAGATAAA

Downstream 100 bases:

>100_bases
TATCAAATCACAAAATCAGATGTGAACTTTTTTTGTTCTAAGCTGGATATGTGGGTATATTTGTGTAAAAACAAATTTAC
CTACATCCTCCCTAATATAG

Product: 3-oxoacyl-[acyl-carrier-protein] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSIKIKNIEYYHPKTSYSNEYFLKHFSEQDIDISGLLNVTGRNKRYVSEDFNENSLTMAIEACKKVIRTANIDVQDINLV
VFVSSTPEYLSPTNAVKVHDALGLSKNTNAYDMNGNCAGMIIAMDQVCRTMKSNNRIKYSLLVGSDLVIRYSRKSEPITY
ANFGESACAVLLENTDDNISDFIDSSSYVDSSLSCYIKFPPDGFSKVLPIDEDTPKDNRIIEWMDFNTDEAFASSVDSIN
EILDRNNLTKDDVKLYCLSQFAKKNIDMIREILEEPDYKFPFVGDRFGYTGVTSPFLALADSVSNGNLKPGDYVILWTVG
AGVVASCILLRY

Sequences:

>Translated_332_residues
MSIKIKNIEYYHPKTSYSNEYFLKHFSEQDIDISGLLNVTGRNKRYVSEDFNENSLTMAIEACKKVIRTANIDVQDINLV
VFVSSTPEYLSPTNAVKVHDALGLSKNTNAYDMNGNCAGMIIAMDQVCRTMKSNNRIKYSLLVGSDLVIRYSRKSEPITY
ANFGESACAVLLENTDDNISDFIDSSSYVDSSLSCYIKFPPDGFSKVLPIDEDTPKDNRIIEWMDFNTDEAFASSVDSIN
EILDRNNLTKDDVKLYCLSQFAKKNIDMIREILEEPDYKFPFVGDRFGYTGVTSPFLALADSVSNGNLKPGDYVILWTVG
AGVVASCILLRY
>Mature_331_residues
SIKIKNIEYYHPKTSYSNEYFLKHFSEQDIDISGLLNVTGRNKRYVSEDFNENSLTMAIEACKKVIRTANIDVQDINLVV
FVSSTPEYLSPTNAVKVHDALGLSKNTNAYDMNGNCAGMIIAMDQVCRTMKSNNRIKYSLLVGSDLVIRYSRKSEPITYA
NFGESACAVLLENTDDNISDFIDSSSYVDSSLSCYIKFPPDGFSKVLPIDEDTPKDNRIIEWMDFNTDEAFASSVDSINE
ILDRNNLTKDDVKLYCLSQFAKKNIDMIREILEEPDYKFPFVGDRFGYTGVTSPFLALADSVSNGNLKPGDYVILWTVGA
GVVASCILLRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=336, Percent_Identity=26.4880952380952, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 37301; Mature: 37170

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKIKNIEYYHPKTSYSNEYFLKHFSEQDIDISGLLNVTGRNKRYVSEDFNENSLTMAI
CEEEEECEEEECCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHH
EACKKVIRTANIDVQDINLVVFVSSTPEYLSPTNAVKVHDALGLSKNTNAYDMNGNCAGM
HHHHHHHHHCCCCEEEEEEEEEECCCCHHCCCCCCEEEHHHHCCCCCCCEEECCCCCEEE
IIAMDQVCRTMKSNNRIKYSLLVGSDLVIRYSRKSEPITYANFGESACAVLLENTDDNIS
EEEHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCEEEECCCCCEEEEEEECCCCCHH
DFIDSSSYVDSSLSCYIKFPPDGFSKVLPIDEDTPKDNRIIEWMDFNTDEAFASSVDSIN
HHHCCCCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
EILDRNNLTKDDVKLYCLSQFAKKNIDMIREILEEPDYKFPFVGDRFGYTGVTSPFLALA
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
DSVSNGNLKPGDYVILWTVGAGVVASCILLRY
HCCCCCCCCCCCEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SIKIKNIEYYHPKTSYSNEYFLKHFSEQDIDISGLLNVTGRNKRYVSEDFNENSLTMAI
EEEEECEEEECCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHH
EACKKVIRTANIDVQDINLVVFVSSTPEYLSPTNAVKVHDALGLSKNTNAYDMNGNCAGM
HHHHHHHHHCCCCEEEEEEEEEECCCCHHCCCCCCEEEHHHHCCCCCCCEEECCCCCEEE
IIAMDQVCRTMKSNNRIKYSLLVGSDLVIRYSRKSEPITYANFGESACAVLLENTDDNIS
EEEHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCEEEECCCCCEEEEEEECCCCCHH
DFIDSSSYVDSSLSCYIKFPPDGFSKVLPIDEDTPKDNRIIEWMDFNTDEAFASSVDSIN
HHHCCCCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
EILDRNNLTKDDVKLYCLSQFAKKNIDMIREILEEPDYKFPFVGDRFGYTGVTSPFLALA
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
DSVSNGNLKPGDYVILWTVGAGVVASCILLRY
HCCCCCCCCCCCEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA