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The map label for this gene is stc [H]

Identifier: 148378595

GI number: 148378595

Start: 691129

End: 692541

Strand: Reverse

Name: stc [H]

Synonym: CBO0594

Alternate gene names: 148378595

Gene position: 692541-691129 (Counterclockwise)

Preceding gene: 148378596

Following gene: 148378593

Centisome position: 17.82

GC content: 29.3

Gene sequence:

>1413_bases
TTGGAAAATTACGATAATCCTATATGTTTAGAGGACCTATTTTCTGATGAAAATGGTGAAAAATTTTTATCTATTTCTGT
TCTTCAAACAGCTTTTAATGTAGCTTATGAAGGTCTTATTCTTATTGATGAAAATTATAACATATTAAAAATAAACACCA
TGGGTTTAAACATATTAAATTCTACAGAGGATAAATTAAAAAAATATTCAATAAAAGATATAATAAGAAATTACAAGTTT
ATAGATGATTGTCTACAAAATGGGGTTCATAAATTTAGTATAGACTCCTCTTTTCTTATAAACAATAATTCTATAAGATG
CATTACAAATATAATGCCTGTAAAGCTTCAGGATTCTATTATAGGGGCTATTATATCTATAAGAGATACAAGACATATAC
ATAAATTAGTTAACAATGTAGTTGGCTATAAAGCCTCCTATACTTTTGATGACATAATAACCAAAAATCAAAAAATGAAA
AGCATAATAGAATTAGCCAAAAAAGCTTCTGAATCTGATTGCAGTATTTTAATAGACGGTAATAGTGGTACTGGTAAAGA
ACTATTTGCTCAAGCTATTCATAACCATAGCAACAGATGTCACGGTCCCTTTGTTGCGGTAAATTGCGCTGCTATTCCTA
GAGAATTAGTGGAAAGTGAACTATTTGGATATGAAAAAGGCGCTTTCACAGGAGCCTCTAAGGGTGGCTATCCTGGTAAA
TTTGAGTTGGCTGATGGTGGAACAATATTTTTAGATGAAATTGGGGAACTACCATTAGATATTCAATCTAAACTATTAAG
AGTTTTAGACAACTTAAAAATAATGCGAGTAGGTGGTACTCACGAAAAGAAAATAGATATCCGAGTCCTAGCAGCTACTA
ACAGAAATTTATCAGAAGAAGTTTCTAATAAAAACTTTAGAGGAGATCTTTATTATAGATTAAACGTTATAAATGTTCAT
CTTATCCCTTTAAAAGATAGGGTAGAGGATGTTGAAGCCTTAACCAACTGTTTTGTAGATAAACTAAATATTAAAAACCC
AGGCAACTTTAAAAAAATAGCTCCTGAATTTATGGATAAACTTAAAGCTTACCATTGGCCTGGAAATGTGCGTGAACTTA
GAAATATAGTAGAAAGAAGCTACTATATTTGCGAAGATAATATTATTACAGATAAATTCTTAAATAACAAGTTAATGAAA
AATGAACATCATAACTGTTGCATTGGAAAGGAAGAACCTATAGTTCCATTAGATATTTTAGAACATAAGGCCATAGAAAA
GGCTCTAATCCATTGTAAAGGCAATATAGTACAGGCCTCTGAATTATTGGGTATAAGTAGAGCAACTATATATAGAAAAA
TAAATAAATATAATATAGATTTAAATGAAATATTAGAAGATAAACAGAATTAA

Upstream 100 bases:

>100_bases
ACTAATTGTATATATATGGGCTCTTAATATATATTTGATTTTATGTTATACTTAATTAATCACATTTTTAGGACCAATGA
TTAATACTGAGGTGATTTTT

Downstream 100 bases:

>100_bases
ACTAATTAAGCATTATTTATAAATATGAATTTAGTTATATTATATAAAATAGGGTTATGTTAAGAAAATATAATGTTAGT
ATAATAATTTCTTAACATAA

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MENYDNPICLEDLFSDENGEKFLSISVLQTAFNVAYEGLILIDENYNILKINTMGLNILNSTEDKLKKYSIKDIIRNYKF
IDDCLQNGVHKFSIDSSFLINNNSIRCITNIMPVKLQDSIIGAIISIRDTRHIHKLVNNVVGYKASYTFDDIITKNQKMK
SIIELAKKASESDCSILIDGNSGTGKELFAQAIHNHSNRCHGPFVAVNCAAIPRELVESELFGYEKGAFTGASKGGYPGK
FELADGGTIFLDEIGELPLDIQSKLLRVLDNLKIMRVGGTHEKKIDIRVLAATNRNLSEEVSNKNFRGDLYYRLNVINVH
LIPLKDRVEDVEALTNCFVDKLNIKNPGNFKKIAPEFMDKLKAYHWPGNVRELRNIVERSYYICEDNIITDKFLNNKLMK
NEHHNCCIGKEEPIVPLDILEHKAIEKALIHCKGNIVQASELLGISRATIYRKINKYNIDLNEILEDKQN

Sequences:

>Translated_470_residues
MENYDNPICLEDLFSDENGEKFLSISVLQTAFNVAYEGLILIDENYNILKINTMGLNILNSTEDKLKKYSIKDIIRNYKF
IDDCLQNGVHKFSIDSSFLINNNSIRCITNIMPVKLQDSIIGAIISIRDTRHIHKLVNNVVGYKASYTFDDIITKNQKMK
SIIELAKKASESDCSILIDGNSGTGKELFAQAIHNHSNRCHGPFVAVNCAAIPRELVESELFGYEKGAFTGASKGGYPGK
FELADGGTIFLDEIGELPLDIQSKLLRVLDNLKIMRVGGTHEKKIDIRVLAATNRNLSEEVSNKNFRGDLYYRLNVINVH
LIPLKDRVEDVEALTNCFVDKLNIKNPGNFKKIAPEFMDKLKAYHWPGNVRELRNIVERSYYICEDNIITDKFLNNKLMK
NEHHNCCIGKEEPIVPLDILEHKAIEKALIHCKGNIVQASELLGISRATIYRKINKYNIDLNEILEDKQN
>Mature_470_residues
MENYDNPICLEDLFSDENGEKFLSISVLQTAFNVAYEGLILIDENYNILKINTMGLNILNSTEDKLKKYSIKDIIRNYKF
IDDCLQNGVHKFSIDSSFLINNNSIRCITNIMPVKLQDSIIGAIISIRDTRHIHKLVNNVVGYKASYTFDDIITKNQKMK
SIIELAKKASESDCSILIDGNSGTGKELFAQAIHNHSNRCHGPFVAVNCAAIPRELVESELFGYEKGAFTGASKGGYPGK
FELADGGTIFLDEIGELPLDIQSKLLRVLDNLKIMRVGGTHEKKIDIRVLAATNRNLSEEVSNKNFRGDLYYRLNVINVH
LIPLKDRVEDVEALTNCFVDKLNIKNPGNFKKIAPEFMDKLKAYHWPGNVRELRNIVERSYYICEDNIITDKFLNNKLMK
NEHHNCCIGKEEPIVPLDILEHKAIEKALIHCKGNIVQASELLGISRATIYRKINKYNIDLNEILEDKQN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=338, Percent_Identity=41.7159763313609, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI87082117, Length=327, Percent_Identity=40.3669724770642, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1790299, Length=338, Percent_Identity=39.3491124260355, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=37.7777777777778, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI1789087, Length=343, Percent_Identity=37.9008746355685, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=39.1975308641975, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1790437, Length=325, Percent_Identity=39.0769230769231, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786524, Length=341, Percent_Identity=37.2434017595308, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787583, Length=437, Percent_Identity=31.8077803203661, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=332, Percent_Identity=36.7469879518072, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI87082152, Length=227, Percent_Identity=46.2555066079295, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87081858, Length=434, Percent_Identity=26.036866359447, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789828, Length=249, Percent_Identity=34.136546184739, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53328; Mature: 53328

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYDNPICLEDLFSDENGEKFLSISVLQTAFNVAYEGLILIDENYNILKINTMGLNILN
CCCCCCCEEHHHHHCCCCCCEEEEHHHHHHHHHHHHCCEEEEECCCCEEEEEECCEEEEC
STEDKLKKYSIKDIIRNYKFIDDCLQNGVHKFSIDSSFLINNNSIRCITNIMPVKLQDSI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEEECCCCEEEHHHH
IGAIISIRDTRHIHKLVNNVVGYKASYTFDDIITKNQKMKSIIELAKKASESDCSILIDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEC
NSGTGKELFAQAIHNHSNRCHGPFVAVNCAAIPRELVESELFGYEKGAFTGASKGGYPGK
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
FELADGGTIFLDEIGELPLDIQSKLLRVLDNLKIMRVGGTHEKKIDIRVLAATNRNLSEE
EEECCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCCCHHHH
VSNKNFRGDLYYRLNVINVHLIPLKDRVEDVEALTNCFVDKLNIKNPGNFKKIAPEFMDK
HCCCCCCCEEEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LKAYHWPGNVRELRNIVERSYYICEDNIITDKFLNNKLMKNEHHNCCIGKEEPIVPLDIL
HHHCCCCCCHHHHHHHHHHCEEEECCCEEHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHH
EHKAIEKALIHCKGNIVQASELLGISRATIYRKINKYNIDLNEILEDKQN
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
>Mature Secondary Structure
MENYDNPICLEDLFSDENGEKFLSISVLQTAFNVAYEGLILIDENYNILKINTMGLNILN
CCCCCCCEEHHHHHCCCCCCEEEEHHHHHHHHHHHHCCEEEEECCCCEEEEEECCEEEEC
STEDKLKKYSIKDIIRNYKFIDDCLQNGVHKFSIDSSFLINNNSIRCITNIMPVKLQDSI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEEECCCCEEEHHHH
IGAIISIRDTRHIHKLVNNVVGYKASYTFDDIITKNQKMKSIIELAKKASESDCSILIDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEC
NSGTGKELFAQAIHNHSNRCHGPFVAVNCAAIPRELVESELFGYEKGAFTGASKGGYPGK
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
FELADGGTIFLDEIGELPLDIQSKLLRVLDNLKIMRVGGTHEKKIDIRVLAATNRNLSEE
EEECCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCCCHHHH
VSNKNFRGDLYYRLNVINVHLIPLKDRVEDVEALTNCFVDKLNIKNPGNFKKIAPEFMDK
HCCCCCCCEEEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LKAYHWPGNVRELRNIVERSYYICEDNIITDKFLNNKLMKNEHHNCCIGKEEPIVPLDIL
HHHCCCCCCHHHHHHHHHHCEEEECCCEEHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHH
EHKAIEKALIHCKGNIVQASELLGISRATIYRKINKYNIDLNEILEDKQN
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA