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The map label for this gene is amiC [H]

Identifier: 148361163

GI number: 148361163

Start: 3397163

End: 3398545

Strand: Reverse

Name: amiC [H]

Synonym: LPC_3137

Alternate gene names: 148361163

Gene position: 3398545-3397163 (Counterclockwise)

Preceding gene: 148361164

Following gene: 148361162

Centisome position: 95.03

GC content: 41.58

Gene sequence:

>1383_bases
ATGCATGTTAATGAGTATATCCACTATGATGTGCAGGAGCTCGCTAAACTGATAAAAAACCATCAGGTTGGTGCTGAGGA
AGTTTTGCGGTGTGCGCAAGAACGCCTATATCAAGTGAATCCTTCATTAAATGCCGTAGTTACAGATTGTTTTGAATATG
CGCATCAATGCCTTGCGAAAATGAAAGGTAACGAGCCCTATTACGGTGTTCCGTTATTAGTCAAGGATCTGGGCCATGCC
ATAGAGGGCATTCGACTAACGGAAGGGTCAAGGTTTTTTGCAAATAATCTGGCTGAGATAAACAGTGATTTGATTAATAA
ATTGATTGCTCTTGGTTTTGTACCATTTGCAAAAACAAATACTTCAGAATTAGGCCTTTCCTGCGTTACTGACTCTAATT
TATTTGGGCCTTGCAGAAATCCTTTTGATACTATGAGAACGGCAGGCGGATCTTCTGGTGGTTCTGCTGCTGCCATAATG
GCAGGGATAGCGCCTGTGGCTACGGCAAGCGATGGAGGCGGGTCGATTCGTATTCCAGCGGCTTGTTGTGGTTTGTTTGG
ATTCAAACCGACACCAGGTCTGGTTCCCTCAGGGCCATGGGTTGATGAAGCATGGTCCGGGATGGCGACCAGTTTTATAC
TCTCTCGTTCCATGAGTGATGCTATTGCATTGTTTAAAAATGTAATAAACCCCATGCGACTTAACAGACTATCGAGAAAG
AAAAAAAAATTGCTTATTACCGAGTTGACAGGCGCTTTTGCCGAGGTACCAATTGCAAGGGAATGCCAGGAGGCGGTAGA
GAAAATAAAAGAAATCCTGAAAAATTCAGGTCACAGATTAAATGAAGTGCACTTGCCATTGGATCTGCAAGTTATCAGTT
CATGCGCCCATACTTTAATTGCAGCGAGCACTTATGCGAAAGTAAAAACTCAAGAACAAATCAGTGGCAGAAAACCAATG
ATTCATGAATTGGAACCCATAACATGGGAATTTTATTACAGAGGAAAAATGGTCTCCGCTTATGAATTCATTATTGCCAA
AAACAAGCTATACCAATCACTAAGACCTCTGCATCAATTATTGGAAAAAACAGACATTGTATTAACTCCTGCATTGGCTC
AACTACCCCTGTTAATCGGTCATTTGCGAATTGATGAGGAATTCAATAAGTATCTACAAAAAAAGAAAGAATTTTCACCT
TTTACTTCCCTGTTTAATCAAGGTGGATTACCCGCTATGACTGTACCAGTTATGTTCCACCATCATTTGCCTGTCTCTGT
GCAAATGGGTTCAGCAAAAGGCAATGATTTGCTCTTATTGGAGTTGGCTCATGAATTACAGCCTGTGCTGCCAAAAAATA
TCACGCCTGCATCAATTCCTTGA

Upstream 100 bases:

>100_bases
TCAGGCGACTATGATAACAACAGCTATAATGTTATAGATAACCTTGTAAAGAGTAATGTTCTCTCTTTATAAAGCTCTCT
GGCTATTGTAGGAATTGAGT

Downstream 100 bases:

>100_bases
TGCTGATTTTTTGTAAGTTTTCATTTATCGAACCTTGTGTTAAGTTAACTGTAGCTTTTCATAAAAATAAGAATAAGTGA
TTGTTTTTTATAGCTATAGT

Product: 6-aminohexanoate-cyclic-dimer hydrolase

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MHVNEYIHYDVQELAKLIKNHQVGAEEVLRCAQERLYQVNPSLNAVVTDCFEYAHQCLAKMKGNEPYYGVPLLVKDLGHA
IEGIRLTEGSRFFANNLAEINSDLINKLIALGFVPFAKTNTSELGLSCVTDSNLFGPCRNPFDTMRTAGGSSGGSAAAIM
AGIAPVATASDGGGSIRIPAACCGLFGFKPTPGLVPSGPWVDEAWSGMATSFILSRSMSDAIALFKNVINPMRLNRLSRK
KKKLLITELTGAFAEVPIARECQEAVEKIKEILKNSGHRLNEVHLPLDLQVISSCAHTLIAASTYAKVKTQEQISGRKPM
IHELEPITWEFYYRGKMVSAYEFIIAKNKLYQSLRPLHQLLEKTDIVLTPALAQLPLLIGHLRIDEEFNKYLQKKKEFSP
FTSLFNQGGLPAMTVPVMFHHHLPVSVQMGSAKGNDLLLLELAHELQPVLPKNITPASIP

Sequences:

>Translated_460_residues
MHVNEYIHYDVQELAKLIKNHQVGAEEVLRCAQERLYQVNPSLNAVVTDCFEYAHQCLAKMKGNEPYYGVPLLVKDLGHA
IEGIRLTEGSRFFANNLAEINSDLINKLIALGFVPFAKTNTSELGLSCVTDSNLFGPCRNPFDTMRTAGGSSGGSAAAIM
AGIAPVATASDGGGSIRIPAACCGLFGFKPTPGLVPSGPWVDEAWSGMATSFILSRSMSDAIALFKNVINPMRLNRLSRK
KKKLLITELTGAFAEVPIARECQEAVEKIKEILKNSGHRLNEVHLPLDLQVISSCAHTLIAASTYAKVKTQEQISGRKPM
IHELEPITWEFYYRGKMVSAYEFIIAKNKLYQSLRPLHQLLEKTDIVLTPALAQLPLLIGHLRIDEEFNKYLQKKKEFSP
FTSLFNQGGLPAMTVPVMFHHHLPVSVQMGSAKGNDLLLLELAHELQPVLPKNITPASIP
>Mature_460_residues
MHVNEYIHYDVQELAKLIKNHQVGAEEVLRCAQERLYQVNPSLNAVVTDCFEYAHQCLAKMKGNEPYYGVPLLVKDLGHA
IEGIRLTEGSRFFANNLAEINSDLINKLIALGFVPFAKTNTSELGLSCVTDSNLFGPCRNPFDTMRTAGGSSGGSAAAIM
AGIAPVATASDGGGSIRIPAACCGLFGFKPTPGLVPSGPWVDEAWSGMATSFILSRSMSDAIALFKNVINPMRLNRLSRK
KKKLLITELTGAFAEVPIARECQEAVEKIKEILKNSGHRLNEVHLPLDLQVISSCAHTLIAASTYAKVKTQEQISGRKPM
IHELEPITWEFYYRGKMVSAYEFIIAKNKLYQSLRPLHQLLEKTDIVLTPALAQLPLLIGHLRIDEEFNKYLQKKKEFSP
FTSLFNQGGLPAMTVPVMFHHHLPVSVQMGSAKGNDLLLLELAHELQPVLPKNITPASIP

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=199, Percent_Identity=33.6683417085427, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI222831590, Length=507, Percent_Identity=23.2741617357002, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990152, Length=192, Percent_Identity=34.8958333333333, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17537465, Length=199, Percent_Identity=31.1557788944724, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17543272, Length=447, Percent_Identity=25.503355704698, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17556264, Length=306, Percent_Identity=27.1241830065359, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538252, Length=311, Percent_Identity=27.0096463022508, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538254, Length=295, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556276, Length=306, Percent_Identity=28.4313725490196, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556278, Length=306, Percent_Identity=28.4313725490196, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=396, Percent_Identity=26.2626262626263, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320448, Length=238, Percent_Identity=30.2521008403361, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24648435, Length=465, Percent_Identity=26.4516129032258, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24648437, Length=465, Percent_Identity=26.4516129032258, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45550774, Length=465, Percent_Identity=26.4516129032258, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356731, Length=491, Percent_Identity=26.2729124236253, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644968, Length=207, Percent_Identity=34.2995169082126, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI161078093, Length=488, Percent_Identity=26.2295081967213, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24648441, Length=398, Percent_Identity=25.3768844221106, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648439, Length=398, Percent_Identity=25.3768844221106, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652985, Length=479, Percent_Identity=25.4697286012526, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19922090, Length=479, Percent_Identity=25.4697286012526, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24652981, Length=479, Percent_Identity=25.4697286012526, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24652983, Length=479, Percent_Identity=25.4697286012526, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648113, Length=430, Percent_Identity=25.8139534883721, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 50626; Mature: 50626

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVNEYIHYDVQELAKLIKNHQVGAEEVLRCAQERLYQVNPSLNAVVTDCFEYAHQCLAK
CCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
MKGNEPYYGVPLLVKDLGHAIEGIRLTEGSRFFANNLAEINSDLINKLIALGFVPFAKTN
HCCCCCCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TSELGLSCVTDSNLFGPCRNPFDTMRTAGGSSGGSAAAIMAGIAPVATASDGGGSIRIPA
CHHCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHH
ACCGLFGFKPTPGLVPSGPWVDEAWSGMATSFILSRSMSDAIALFKNVINPMRLNRLSRK
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
KKKLLITELTGAFAEVPIARECQEAVEKIKEILKNSGHRLNEVHLPLDLQVISSCAHTLI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
AASTYAKVKTQEQISGRKPMIHELEPITWEFYYRGKMVSAYEFIIAKNKLYQSLRPLHQL
HHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LEKTDIVLTPALAQLPLLIGHLRIDEEFNKYLQKKKEFSPFTSLFNQGGLPAMTVPVMFH
HHHCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEHHHHHC
HHLPVSVQMGSAKGNDLLLLELAHELQPVLPKNITPASIP
CCCCEEEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MHVNEYIHYDVQELAKLIKNHQVGAEEVLRCAQERLYQVNPSLNAVVTDCFEYAHQCLAK
CCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
MKGNEPYYGVPLLVKDLGHAIEGIRLTEGSRFFANNLAEINSDLINKLIALGFVPFAKTN
HCCCCCCCCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TSELGLSCVTDSNLFGPCRNPFDTMRTAGGSSGGSAAAIMAGIAPVATASDGGGSIRIPA
CHHCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHH
ACCGLFGFKPTPGLVPSGPWVDEAWSGMATSFILSRSMSDAIALFKNVINPMRLNRLSRK
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
KKKLLITELTGAFAEVPIARECQEAVEKIKEILKNSGHRLNEVHLPLDLQVISSCAHTLI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHH
AASTYAKVKTQEQISGRKPMIHELEPITWEFYYRGKMVSAYEFIIAKNKLYQSLRPLHQL
HHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LEKTDIVLTPALAQLPLLIGHLRIDEEFNKYLQKKKEFSPFTSLFNQGGLPAMTVPVMFH
HHHCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEHHHHHC
HHLPVSVQMGSAKGNDLLLLELAHELQPVLPKNITPASIP
CCCCEEEEECCCCCCCEEHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA