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The map label for this gene is alf1

Identifier: 148360914

GI number: 148360914

Start: 564936

End: 565946

Strand: Reverse

Name: alf1

Synonym: LPC_2874

Alternate gene names: NA

Gene position: 565946-564936 (Counterclockwise)

Preceding gene: 148360913

Following gene: 148360916

Centisome position: 15.82

GC content: 40.36

Gene sequence:

>1011_bases
ATGAGTTATGAAGAATTATCAAATACCATGGAGCAAATGCTGCATGAAGGAAAAGGTATTTTAGCTGCAGATGAAAGCAA
CAGTACAATTGGCAAGCGCTTTGCGTCAATCAATACAGAAAATACCGAGGAGAATCGAAGAGATTATCGCTTGTTACTTG
CGACCACTCCTGATTTAGAACAGTATATCAACGGCGTCATTTTATTTGAGGAAACTTTTACTCAAACTGATGAGCATGGA
ACACCAATTCCTGAGCTTTTTGCTAATAAAGGCATTATTCCTGGAATTAAAGTAGACAAAGGGCTTGTTGATTTAGCCAA
TACAGAACATGAAAAAGTTACCCAGGGATTAGATGGTTTAACCGAGCGCCTGCTTCATTTTAAAAAATTAGGTGCAAAAT
TCGCAAAATGGAGAAACGTTTATTCAATTTCCGAATACACTCCCAGCCTAACTGCAATCAAAACAGGAGCTGAAAATTTG
GGCCGTTACGCTGCTGCTTGTCAATCAGTCGGCATCGTTCCAATTGTTGAACCTGAAGTATTAATGGATGGCAACCATAG
CATAGAACATTGTGCTGAAGTCTGTGAAATGGTTCTCCATGAGCTGTTTCATACCTTGTTTATCCATCAAGTGGAGTTGG
AGCATATTATACTTAAACCGAGTATGGTTACCTGTGGTAAAGAAGTGACCCCGTTTAGCGATCCTGAAGAAGTGGCTGAC
TACACCATTAGTGTATTTCGTAATAATGTTCCAGCGTCAGTACCCACCATTAATTTCCTCTCCGGTGGCCAAACACCCCA
ACAGGCTACCGCTAACTTGAATGCAATCAATCAAATTGGCCACCAACCCTGGTTATTAAGTTTTTCATTTGGAAGAGCAT
TACAAGAGGATTGCTTAAAGGAATGGTGTGGAAACAAAGCAAATATTGCCAAAGCGCAAGAGGCTTTAATTAAGAGAGCC
CGCTTAAACAGTATGGCTTGTTTGGGTGAATACCAAAACGACATGGAGTAA

Upstream 100 bases:

>100_bases
AACCCGGATTTGACAAAAGATGACTAGTCGTTATTTAAATTTAATAGGTGCCAAACCACTTCGAAAGGTCGACACCCGAT
AATGAGGAGATAAACACGTT

Downstream 100 bases:

>100_bases
AGTTGCAATAGCGACAGAACCTTCTCTCGACCAGGAAGACTGTCGCTTTAATCTTAATCATACAAGGCTTACTAAAAACC
CCAAGGTCAAGGCAAAAAAA

Product: fructose bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLEQYINGVILFEETFTQTDEHG
TPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGLTERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENL
GRYAAACQSVGIVPIVEPEVLMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVTPFSDPEEVAD
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLKEWCGNKANIAKAQEALIKRA
RLNSMACLGEYQNDME

Sequences:

>Translated_336_residues
MSYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLEQYINGVILFEETFTQTDEHG
TPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGLTERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENL
GRYAAACQSVGIVPIVEPEVLMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVTPFSDPEEVAD
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLKEWCGNKANIAKAQEALIKRA
RLNSMACLGEYQNDME
>Mature_335_residues
SYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLEQYINGVILFEETFTQTDEHGT
PIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGLTERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENLG
RYAAACQSVGIVPIVEPEVLMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVTPFSDPEEVADY
TISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLKEWCGNKANIAKAQEALIKRAR
LNSMACLGEYQNDME

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=330, Percent_Identity=52.1212121212121, Blast_Score=327, Evalue=9e-90,
Organism=Homo sapiens, GI34577110, Length=330, Percent_Identity=52.1212121212121, Blast_Score=327, Evalue=9e-90,
Organism=Homo sapiens, GI4557305, Length=330, Percent_Identity=52.1212121212121, Blast_Score=327, Evalue=9e-90,
Organism=Homo sapiens, GI193794814, Length=330, Percent_Identity=52.1212121212121, Blast_Score=327, Evalue=9e-90,
Organism=Homo sapiens, GI4885063, Length=335, Percent_Identity=49.5522388059701, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI40354205, Length=330, Percent_Identity=48.7878787878788, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI25150450, Length=332, Percent_Identity=51.5060240963855, Blast_Score=333, Evalue=9e-92,
Organism=Caenorhabditis elegans, GI71983985, Length=330, Percent_Identity=50.9090909090909, Blast_Score=321, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI71983990, Length=224, Percent_Identity=51.7857142857143, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI45553577, Length=330, Percent_Identity=50.9090909090909, Blast_Score=320, Evalue=6e-88,
Organism=Drosophila melanogaster, GI24650282, Length=330, Percent_Identity=50.3030303030303, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24650280, Length=330, Percent_Identity=50.3030303030303, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24650278, Length=330, Percent_Identity=50.3030303030303, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI221459619, Length=330, Percent_Identity=50.3030303030303, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24650288, Length=330, Percent_Identity=50.3030303030303, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24650304, Length=330, Percent_Identity=44.5454545454545, Blast_Score=275, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37411; Mature: 37280

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLE
CCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHH
QYINGVILFEETFTQTDEHGTPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGL
HHHCCEEEEEHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHH
TERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENLGRYAAACQSVGIVPIVEPEV
HHHHHHHHHHHHHHHHHHCCEEHHHCCCCHHHHHHCHHHHHHHHHHHHHCCCEEECCCHH
LMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVTPFSDPEEVAD
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCCCCCCCCHHHHHH
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLK
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
EWCGNKANIAKAQEALIKRARLNSMACLGEYQNDME
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYEELSNTMEQMLHEGKGILAADESNSTIGKRFASINTENTEENRRDYRLLLATTPDLE
CHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHH
QYINGVILFEETFTQTDEHGTPIPELFANKGIIPGIKVDKGLVDLANTEHEKVTQGLDGL
HHHCCEEEEEHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHH
TERLLHFKKLGAKFAKWRNVYSISEYTPSLTAIKTGAENLGRYAAACQSVGIVPIVEPEV
HHHHHHHHHHHHHHHHHHCCEEHHHCCCCHHHHHHCHHHHHHHHHHHHHCCCEEECCCHH
LMDGNHSIEHCAEVCEMVLHELFHTLFIHQVELEHIILKPSMVTCGKEVTPFSDPEEVAD
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHCCCCCCCCCCHHHHHH
YTISVFRNNVPASVPTINFLSGGQTPQQATANLNAINQIGHQPWLLSFSFGRALQEDCLK
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
EWCGNKANIAKAQEALIKRARLNSMACLGEYQNDME
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]