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The map label for this gene is dinP [H]

Identifier: 148360791

GI number: 148360791

Start: 685885

End: 686952

Strand: Reverse

Name: dinP [H]

Synonym: LPC_2746

Alternate gene names: 148360791

Gene position: 686952-685885 (Counterclockwise)

Preceding gene: 148360790

Following gene: 148360792

Centisome position: 19.21

GC content: 41.2

Gene sequence:

>1068_bases
ATGAATCCGATAAGAAAAATTATCCATATTGATATGGACTGTTTTTATGCGGCAATTGAAATGCGTGATTTCCCTGAGCT
GGCAAATAAACCTATCGCTGTAGGCGGGGATGCAAAACGTCGTGGAGTCATAGCGACCTGTAATTATGCTGCCCGCCAAT
TTGGCATACGCTCTGCAATGCCAACAGCCCATGCGCTTAAACTTTGCCGAGAATTAATCTTGCGGCCAGTACGTATGGAT
GTATACCAAAAGGAAAGCCAATATATTAGATCCCTATTAACAGAATATACAGACCTCATTGAACCTTTATCATTAGATGA
AGCCTATCTGGATGTCACTGAATCCACACAATGCCAGGGAAGCGCCACCTGGATTGCTGAAGAAATACGCGCCCGAATTT
ATCAAACAAGACAACTCACTGCGAGTGCGGGCATTGCGCCAAATAAGAGTCTCGCAAAAATAGCCAGTGATTGGCATAAA
CCGAATGGGCAAATGGTTATTAGACCTGAGGACGTTAGCGCATTTGTTCTTGATTTACCAGTACGCAAGTTATTTGGTGT
AGGGCCGAAGATGGAGGAAAAATTGGGTGCGCTCAACATTAAAACCTGTGCTGATTTGCAGCGATATTCCGTTGAATATT
TATTACAAAAATTTGGCACCATGGGTCAAAGACTTTATGAATTAGCGCGAGGCATTGATAATCGCCCCGTCAATCCTGAG
CGTATTCGAAAATCCATCAGCGTTGAAGAAACCTATCCAAAAGACTTGCCAAATAGTGAAGCTTGCCTGGCAGTCTTGCC
AGAGCTTATGGCGCGCCTTGAAGCAAGAATACAACGTGCAGGTAAAATTTCTGGCATTCACAATTTATTTGTAAAATTGA
AGTTTAATGACTTTCAGCAAACAACTATTGAACGAGTTATGGACAAACTTGATTTAATCGTTTTACGTCAATTGATACAA
GAAGGTTTTGCCAGAAGAGGCATGCCAGTACGATTATTAGGTATAGGAATTAAATTGAAACAAGAAAATACGTATCAAAG
CGTACAATTGCCATTACTTGACTTATAA

Upstream 100 bases:

>100_bases
AAGTAAAAAATAGTTATTCTGTAGACTAAGCTTTACAGCTTCAAGAAAATCAGCTAAGACCTAATATGAAACCTCTGTTA
TTGCAATCTGTGATTGAAAA

Downstream 100 bases:

>100_bases
AAAGTATCTAAACAGTTGATATCAGATTCTTTCCCAAACTTGCCATAATTATCAGAACTTAATACATCAGCTCTCTTTTT
TATGCAACATCCTGCAATAG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLGALNIKTCADLQRYSVEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPELMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKLDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL

Sequences:

>Translated_355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLGALNIKTCADLQRYSVEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPELMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKLDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
>Mature_355_residues
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAMPTAHALKLCRELILRPVRMD
VYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQGSATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHK
PNGQMVIRPEDVSAFVLDLPVRKLFGVGPKMEEKLGALNIKTCADLQRYSVEYLLQKFGTMGQRLYELARGIDNRPVNPE
RIRKSISVEETYPKDLPNSEACLAVLPELMARLEARIQRAGKISGIHNLFVKLKFNDFQQTTIERVMDKLDLIVLRQLIQ
EGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=328, Percent_Identity=32.6219512195122, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI7706681, Length=329, Percent_Identity=32.5227963525836, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI154350220, Length=315, Percent_Identity=31.7460317460317, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=49.0740740740741, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI5729982, Length=353, Percent_Identity=28.328611898017, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786425, Length=340, Percent_Identity=52.6470588235294, Blast_Score=337, Evalue=7e-94,
Organism=Escherichia coli, GI1787432, Length=229, Percent_Identity=29.2576419213974, Blast_Score=91, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=398, Percent_Identity=32.1608040201005, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=284, Percent_Identity=27.8169014084507, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=343, Percent_Identity=29.7376093294461, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324921, Length=272, Percent_Identity=29.0441176470588, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=30.3405572755418, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=36.9747899159664, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40306; Mature: 40306

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAM
CCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCEEEECHHHHHHHHHHHCC
PTAHALKLCRELILRPVRMDVYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
SATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHKPNGQMVIRPEDVSAFVLDLP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VRKLFGVGPKMEEKLGALNIKTCADLQRYSVEYLLQKFGTMGQRLYELARGIDNRPVNPE
HHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RIRKSISVEETYPKDLPNSEACLAVLPELMARLEARIQRAGKISGIHNLFVKLKFNDFQQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHH
TTIERVMDKLDLIVLRQLIQEGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPIRKIIHIDMDCFYAAIEMRDFPELANKPIAVGGDAKRRGVIATCNYAARQFGIRSAM
CCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCCCCCCEEEECHHHHHHHHHHHCC
PTAHALKLCRELILRPVRMDVYQKESQYIRSLLTEYTDLIEPLSLDEAYLDVTESTQCQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCC
SATWIAEEIRARIYQTRQLTASAGIAPNKSLAKIASDWHKPNGQMVIRPEDVSAFVLDLP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHH
VRKLFGVGPKMEEKLGALNIKTCADLQRYSVEYLLQKFGTMGQRLYELARGIDNRPVNPE
HHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RIRKSISVEETYPKDLPNSEACLAVLPELMARLEARIQRAGKISGIHNLFVKLKFNDFQQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCHHH
TTIERVMDKLDLIVLRQLIQEGFARRGMPVRLLGIGIKLKQENTYQSVQLPLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA