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The map label for this gene is atpD [H]

Identifier: 148360282

GI number: 148360282

Start: 1267181

End: 1268605

Strand: Reverse

Name: atpD [H]

Synonym: LPC_2219

Alternate gene names: 148360282

Gene position: 1268605-1267181 (Counterclockwise)

Preceding gene: 148360281

Following gene: 148360283

Centisome position: 35.47

GC content: 44.77

Gene sequence:

>1425_bases
ATGGGTCATGAATTCAATTGGAAAATGATGGATAAAAACACGGCTGTTGCTCAAACTCATGGAACTCCCATCGGCAGGAT
AATCGAAATCAATGGCCCTGTTGTCCGGATACATTGTAATGTACTACCTCCTTTGCATCAATCTCTTAAAACTTACACGG
ACAGTGATGAATACATTTTGGAAGTGTGTCAGCACCTTGATGAGCATCATGTGAGAGCCATCACGCTCCACCGTGCCTCA
GGATTGCAAAGAGGTTTAATAGTTTATGACCAAGGCACTTCGTTACGAATTCCCGTTTCAAAAGAATGCTTGGGCCGCCT
TTTAAATATTTTTGGTGAGCCATTAGACGGAGCCCCGCCATTAGAAACCCATGAATATCGTGATGTTCTGGCCAACTTCG
CGCCACTTGAAATGACGAGCACTCAAGAAACCATTCTTGAGACTGGAATTAAAGTCATTGATTTACTTTGCCCTTTCGTC
AGAGGATGTAAAACAGGATTGTTTGGTGGTGCAGGAGTTGGAAAAACCGTACTCCTGATGGAATTGATGCATGCCATTAT
TCAATTGCATCAAGGAACCTCCGTCTTTGCTGGTGTTGGTGAGCGTATTCGGGAGGGACATGAATTGTGGCATGAGATGA
AATCCGCAGGCGTAATGGATAAAACCCTCATGGTGTTTGGTCAAATGGACGAATCACCGGGAGTGCGTTTTCGCACAGGG
TTATCGGCATTAACTTATGCGGAATATTTGCGTGATACGTTGGGCCATGAGGTTCTTTTTCTTGTGGATAATATTTATCG
TTTTGTGCAAGCCGGCAGTGAAATTTCGGGGTTACTTGGCCGAATGCCGGCTAGTGTCGGTTATCAACCCACCTTAATGA
CTGAGATAGCGGAACTTGAAGAGCGCATGACATCGACTGCAAAAGGAGCAGTGACCTCGGTACAAGCGGTTTATGTTCCG
GCTGATGATATGAGCGATCCGGCGGTGACCGGGATTATTACTCATTTGGATTCCATCATAGTACTCTCTCGCGCACAAGC
AGGCAAAGGCATTTATCCCGCCGTGGATCCCTTAGCTTCCAAGAGTCAATTTATGGATAAAATCCTATTGGGCGAGCGAC
ATTATTCCATTGCACAAGCCGTACGAGAACACCTGGAACGTTATCAAGAATTAGAAGACATGATTTCTATGATGGGGATT
GAAGAGCTTTCTCCTAAAGACCGTGCTATTGTGTTAAGAGCACGTAAACTGCAGCGCTATCTTAGCCAACCCTTCCATGT
CACCAAACTTCAAACAGGAATGGAAGGGAAATCGGTTTCATTAGAACACACATTAACTGATTGCGAATCCTTTCTAAGAG
GCGATTACGATGAATTTTCAGAAGAAGCGTGTTACATGAGGGGTGCCATGGATAAAGGGAGATAA

Upstream 100 bases:

>100_bases
CTGTTATTAATTAGCATTTTGCTATCTGTTTTCAAACTCTGTTATATTAAAATTCCATAAAGTGATGTAAAAATAGAGAG
AATAGGACGACACCTAATTC

Downstream 100 bases:

>100_bases
CGACGGACATGGAGCTTTTTACTATCCATCTTAAGAGTGCCACACAATATGAAAAAATCGATAAGGTCATCAGTTTTGTG
GGTGAGGATGCTTCTGGGCA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MGHEFNWKMMDKNTAVAQTHGTPIGRIIEINGPVVRIHCNVLPPLHQSLKTYTDSDEYILEVCQHLDEHHVRAITLHRAS
GLQRGLIVYDQGTSLRIPVSKECLGRLLNIFGEPLDGAPPLETHEYRDVLANFAPLEMTSTQETILETGIKVIDLLCPFV
RGCKTGLFGGAGVGKTVLLMELMHAIIQLHQGTSVFAGVGERIREGHELWHEMKSAGVMDKTLMVFGQMDESPGVRFRTG
LSALTYAEYLRDTLGHEVLFLVDNIYRFVQAGSEISGLLGRMPASVGYQPTLMTEIAELEERMTSTAKGAVTSVQAVYVP
ADDMSDPAVTGIITHLDSIIVLSRAQAGKGIYPAVDPLASKSQFMDKILLGERHYSIAQAVREHLERYQELEDMISMMGI
EELSPKDRAIVLRARKLQRYLSQPFHVTKLQTGMEGKSVSLEHTLTDCESFLRGDYDEFSEEACYMRGAMDKGR

Sequences:

>Translated_474_residues
MGHEFNWKMMDKNTAVAQTHGTPIGRIIEINGPVVRIHCNVLPPLHQSLKTYTDSDEYILEVCQHLDEHHVRAITLHRAS
GLQRGLIVYDQGTSLRIPVSKECLGRLLNIFGEPLDGAPPLETHEYRDVLANFAPLEMTSTQETILETGIKVIDLLCPFV
RGCKTGLFGGAGVGKTVLLMELMHAIIQLHQGTSVFAGVGERIREGHELWHEMKSAGVMDKTLMVFGQMDESPGVRFRTG
LSALTYAEYLRDTLGHEVLFLVDNIYRFVQAGSEISGLLGRMPASVGYQPTLMTEIAELEERMTSTAKGAVTSVQAVYVP
ADDMSDPAVTGIITHLDSIIVLSRAQAGKGIYPAVDPLASKSQFMDKILLGERHYSIAQAVREHLERYQELEDMISMMGI
EELSPKDRAIVLRARKLQRYLSQPFHVTKLQTGMEGKSVSLEHTLTDCESFLRGDYDEFSEEACYMRGAMDKGR
>Mature_473_residues
GHEFNWKMMDKNTAVAQTHGTPIGRIIEINGPVVRIHCNVLPPLHQSLKTYTDSDEYILEVCQHLDEHHVRAITLHRASG
LQRGLIVYDQGTSLRIPVSKECLGRLLNIFGEPLDGAPPLETHEYRDVLANFAPLEMTSTQETILETGIKVIDLLCPFVR
GCKTGLFGGAGVGKTVLLMELMHAIIQLHQGTSVFAGVGERIREGHELWHEMKSAGVMDKTLMVFGQMDESPGVRFRTGL
SALTYAEYLRDTLGHEVLFLVDNIYRFVQAGSEISGLLGRMPASVGYQPTLMTEIAELEERMTSTAKGAVTSVQAVYVPA
DDMSDPAVTGIITHLDSIIVLSRAQAGKGIYPAVDPLASKSQFMDKILLGERHYSIAQAVREHLERYQELEDMISMMGIE
ELSPKDRAIVLRARKLQRYLSQPFHVTKLQTGMEGKSVSLEHTLTDCESFLRGDYDEFSEEACYMRGAMDKGR

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=469, Percent_Identity=49.0405117270789, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI19913424, Length=293, Percent_Identity=28.3276450511945, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19913426, Length=338, Percent_Identity=25.4437869822485, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI19913428, Length=353, Percent_Identity=23.7960339943343, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI50345984, Length=346, Percent_Identity=23.4104046242775, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4757810, Length=346, Percent_Identity=23.4104046242775, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1790170, Length=452, Percent_Identity=49.1150442477876, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1788251, Length=351, Percent_Identity=32.7635327635328, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1790172, Length=393, Percent_Identity=25.6997455470738, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=460, Percent_Identity=49.1304347826087, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17510931, Length=430, Percent_Identity=23.7209302325581, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=399, Percent_Identity=24.5614035087719, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=305, Percent_Identity=27.5409836065574, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=314, Percent_Identity=24.5222929936306, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=314, Percent_Identity=24.5222929936306, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988074, Length=260, Percent_Identity=24.2307692307692, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322581, Length=474, Percent_Identity=48.3122362869198, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6319603, Length=404, Percent_Identity=26.2376237623762, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=357, Percent_Identity=23.249299719888, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320016, Length=224, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24638766, Length=455, Percent_Identity=49.8901098901099, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI28574560, Length=418, Percent_Identity=51.1961722488038, Blast_Score=420, Evalue=1e-118,
Organism=Drosophila melanogaster, GI281361666, Length=339, Percent_Identity=25.3687315634218, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24646341, Length=339, Percent_Identity=25.3687315634218, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17136796, Length=339, Percent_Identity=25.3687315634218, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583992, Length=294, Percent_Identity=27.2108843537415, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129479, Length=308, Percent_Identity=25.6493506493506, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24583988, Length=293, Percent_Identity=26.962457337884, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24583986, Length=293, Percent_Identity=26.962457337884, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24583984, Length=293, Percent_Identity=26.962457337884, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24658560, Length=304, Percent_Identity=23.0263157894737, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24638768, Length=90, Percent_Identity=41.1111111111111, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 52747; Mature: 52616

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHEFNWKMMDKNTAVAQTHGTPIGRIIEINGPVVRIHCNVLPPLHQSLKTYTDSDEYIL
CCCCCCCEEECCCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHHHHHCCCCHHHHH
EVCQHLDEHHVRAITLHRASGLQRGLIVYDQGTSLRIPVSKECLGRLLNIFGEPLDGAPP
HHHHHHHHHHHEEEEEEHHCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
LETHEYRDVLANFAPLEMTSTQETILETGIKVIDLLCPFVRGCKTGLFGGAGVGKTVLLM
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ELMHAIIQLHQGTSVFAGVGERIREGHELWHEMKSAGVMDKTLMVFGQMDESPGVRFRTG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHHH
LSALTYAEYLRDTLGHEVLFLVDNIYRFVQAGSEISGLLGRMPASVGYQPTLMTEIAELE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
ERMTSTAKGAVTSVQAVYVPADDMSDPAVTGIITHLDSIIVLSRAQAGKGIYPAVDPLAS
HHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KSQFMDKILLGERHYSIAQAVREHLERYQELEDMISMMGIEELSPKDRAIVLRARKLQRY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LSQPFHVTKLQTGMEGKSVSLEHTLTDCESFLRGDYDEFSEEACYMRGAMDKGR
HCCCCEEEHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GHEFNWKMMDKNTAVAQTHGTPIGRIIEINGPVVRIHCNVLPPLHQSLKTYTDSDEYIL
CCCCCCEEECCCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHHHHHCCCCHHHHH
EVCQHLDEHHVRAITLHRASGLQRGLIVYDQGTSLRIPVSKECLGRLLNIFGEPLDGAPP
HHHHHHHHHHHEEEEEEHHCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
LETHEYRDVLANFAPLEMTSTQETILETGIKVIDLLCPFVRGCKTGLFGGAGVGKTVLLM
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ELMHAIIQLHQGTSVFAGVGERIREGHELWHEMKSAGVMDKTLMVFGQMDESPGVRFRTG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHHH
LSALTYAEYLRDTLGHEVLFLVDNIYRFVQAGSEISGLLGRMPASVGYQPTLMTEIAELE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
ERMTSTAKGAVTSVQAVYVPADDMSDPAVTGIITHLDSIIVLSRAQAGKGIYPAVDPLAS
HHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KSQFMDKILLGERHYSIAQAVREHLERYQELEDMISMMGIEELSPKDRAIVLRARKLQRY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LSQPFHVTKLQTGMEGKSVSLEHTLTDCESFLRGDYDEFSEEACYMRGAMDKGR
HCCCCEEEHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA