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The map label for this gene is int [H]

Identifier: 148360267

GI number: 148360267

Start: 1279688

End: 1280869

Strand: Reverse

Name: int [H]

Synonym: LPC_2204

Alternate gene names: 148360267

Gene position: 1280869-1279688 (Counterclockwise)

Preceding gene: 148360264

Following gene: 148360268

Centisome position: 35.81

GC content: 37.06

Gene sequence:

>1182_bases
ATGAAATTTATCGATAGCTATATTAAAAATCTCGCGCCAGAGACCACCTGGTTTGAAAAAATAGAATCTTCTGGATTAGG
TATTAGAGTAATGCCAAGTGGTAATAAATCTTGGTTTTACCGTTTTAGTATGAATGGTAAACGTCAAAAAATGACCTTAG
GAAAATATCCAGCTATTAGTCTAAAACAGGCTCGTGAATATCTTGCTAAAGCGCAAAGTTTAAAAGAGCAAGGTATAAAT
CCTATAGAAAATACCAAGCTAGAAAAATTAAAAGAAGACAATACCTTTTCAAAATTAATACAGTCTTGGTACGAAAATTA
TGCCGTTAAAAATAGAAAGCAACCACGCCCTATCAAATATCAGATTGACTCAGAAATAATTCCTCTACTAGGCGATACTG
TACTTGATAAGTTACAAACCAAAGATATTACAATCGCCCTTGACAAAATAGTACAACGAGGAGCGCCAATTCATGCGAAT
CGCATTCTCAGCACTATTAAACAAGTTCTAAACTATGCAGTGAGTCGTGGTTATATTCAATATAATCCAGCTACCAATAT
ACGATCACGTGATATCGGTGGTATTGAAAAGCCCAGGGAGCGGGTACTATCGCCCGAAGAAATAAGAATAATATGGAAAT
TCCTTGAAAGCGATAAAAGCCAAATGTCTGAATCAGCCAGGTTAGCAATTAAAGTTATTATACTTACTGGTGTTAGAACA
GGTGAAATCCGACTGGCACAATGGCATCAATTTGATTTTGAGCAATCTTTATGGACTATTCCTCCCGAGCATTCAAAAGG
AGGAATAACTGTAAAAATACACTTGAGTGAACTTACAAAAAAATTACTACTTCAGTTTAAAGAACAATCTGTCTCCCCTT
TTGTAATTCCAGGCATAACAATCGATGTTCCTATGTCCAAAGATGCCCTACCACGTGCAATTAAAAGAATCCAGACTCGG
GTAGGAGTTCCTGAATGGACTGCTCATGATTTGAGGAGAACCTTTGCCACACAATTGGGTGAGTCACTTAATATTGATCC
CGTGGTGATAGAAAAATGTCTTGGCCACAAAATGCCCCGTATTATGGCTACTTATAATAAAAATGAGATGCTACCCCAAC
GCAAAGAAGCATTGGACGCCTGGGCAAGCCATATTGCAAAATTAATCTCATCAAAGGATTGA

Upstream 100 bases:

>100_bases
AATAATTGAGTTTTAGCAATTCAATTAGTATCATTTGATAATATACCTATACATAAATTTTGGTACCAAAAATGGTACCA
AAATAAAAAGGACTGTGTAG

Downstream 100 bases:

>100_bases
AAAAGTCATATGAACTGCTCTATAATTAACTTAACACAACCGCCACGCCTAGAGGACATTAGTCCTTGCGTAACCTTGGC
GGTTTTTTTATGCGTATTGC

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKFIDSYIKNLAPETTWFEKIESSGLGIRVMPSGNKSWFYRFSMNGKRQKMTLGKYPAISLKQAREYLAKAQSLKEQGIN
PIENTKLEKLKEDNTFSKLIQSWYENYAVKNRKQPRPIKYQIDSEIIPLLGDTVLDKLQTKDITIALDKIVQRGAPIHAN
RILSTIKQVLNYAVSRGYIQYNPATNIRSRDIGGIEKPRERVLSPEEIRIIWKFLESDKSQMSESARLAIKVIILTGVRT
GEIRLAQWHQFDFEQSLWTIPPEHSKGGITVKIHLSELTKKLLLQFKEQSVSPFVIPGITIDVPMSKDALPRAIKRIQTR
VGVPEWTAHDLRRTFATQLGESLNIDPVVIEKCLGHKMPRIMATYNKNEMLPQRKEALDAWASHIAKLISSKD

Sequences:

>Translated_393_residues
MKFIDSYIKNLAPETTWFEKIESSGLGIRVMPSGNKSWFYRFSMNGKRQKMTLGKYPAISLKQAREYLAKAQSLKEQGIN
PIENTKLEKLKEDNTFSKLIQSWYENYAVKNRKQPRPIKYQIDSEIIPLLGDTVLDKLQTKDITIALDKIVQRGAPIHAN
RILSTIKQVLNYAVSRGYIQYNPATNIRSRDIGGIEKPRERVLSPEEIRIIWKFLESDKSQMSESARLAIKVIILTGVRT
GEIRLAQWHQFDFEQSLWTIPPEHSKGGITVKIHLSELTKKLLLQFKEQSVSPFVIPGITIDVPMSKDALPRAIKRIQTR
VGVPEWTAHDLRRTFATQLGESLNIDPVVIEKCLGHKMPRIMATYNKNEMLPQRKEALDAWASHIAKLISSKD
>Mature_393_residues
MKFIDSYIKNLAPETTWFEKIESSGLGIRVMPSGNKSWFYRFSMNGKRQKMTLGKYPAISLKQAREYLAKAQSLKEQGIN
PIENTKLEKLKEDNTFSKLIQSWYENYAVKNRKQPRPIKYQIDSEIIPLLGDTVLDKLQTKDITIALDKIVQRGAPIHAN
RILSTIKQVLNYAVSRGYIQYNPATNIRSRDIGGIEKPRERVLSPEEIRIIWKFLESDKSQMSESARLAIKVIILTGVRT
GEIRLAQWHQFDFEQSLWTIPPEHSKGGITVKIHLSELTKKLLLQFKEQSVSPFVIPGITIDVPMSKDALPRAIKRIQTR
VGVPEWTAHDLRRTFATQLGESLNIDPVVIEKCLGHKMPRIMATYNKNEMLPQRKEALDAWASHIAKLISSKD

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=383, Percent_Identity=28.7206266318538, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788690, Length=386, Percent_Identity=26.6839378238342, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1788974, Length=404, Percent_Identity=26.7326732673267, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45063; Mature: 45063

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDSYIKNLAPETTWFEKIESSGLGIRVMPSGNKSWFYRFSMNGKRQKMTLGKYPAIS
CCHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHEEECCCCCCCH
LKQAREYLAKAQSLKEQGINPIENTKLEKLKEDNTFSKLIQSWYENYAVKNRKQPRPIKY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
QIDSEIIPLLGDTVLDKLQTKDITIALDKIVQRGAPIHANRILSTIKQVLNYAVSRGYIQ
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEE
YNPATNIRSRDIGGIEKPRERVLSPEEIRIIWKFLESDKSQMSESARLAIKVIILTGVRT
ECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
GEIRLAQWHQFDFEQSLWTIPPEHSKGGITVKIHLSELTKKLLLQFKEQSVSPFVIPGIT
CCEEEEHHHHCCHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEECCEE
IDVPMSKDALPRAIKRIQTRVGVPEWTAHDLRRTFATQLGESLNIDPVVIEKCLGHKMPR
EECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCH
IMATYNKNEMLPQRKEALDAWASHIAKLISSKD
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFIDSYIKNLAPETTWFEKIESSGLGIRVMPSGNKSWFYRFSMNGKRQKMTLGKYPAIS
CCHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHEEECCCCCCCH
LKQAREYLAKAQSLKEQGINPIENTKLEKLKEDNTFSKLIQSWYENYAVKNRKQPRPIKY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
QIDSEIIPLLGDTVLDKLQTKDITIALDKIVQRGAPIHANRILSTIKQVLNYAVSRGYIQ
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEE
YNPATNIRSRDIGGIEKPRERVLSPEEIRIIWKFLESDKSQMSESARLAIKVIILTGVRT
ECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
GEIRLAQWHQFDFEQSLWTIPPEHSKGGITVKIHLSELTKKLLLQFKEQSVSPFVIPGIT
CCEEEEHHHHCCHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEECCEE
IDVPMSKDALPRAIKRIQTRVGVPEWTAHDLRRTFATQLGESLNIDPVVIEKCLGHKMPR
EECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCH
IMATYNKNEMLPQRKEALDAWASHIAKLISSKD
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]