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The map label for this gene is insF1 [C]

Identifier: 148360223

GI number: 148360223

Start: 1323662

End: 1324489

Strand: Reverse

Name: insF1 [C]

Synonym: LPC_2156

Alternate gene names: 148360223

Gene position: 1324489-1323662 (Counterclockwise)

Preceding gene: 148360222

Following gene: 148360233

Centisome position: 37.03

GC content: 39.13

Gene sequence:

>828_bases
ATGTGCCAACTCCTGGGCATTACACGGCATGGATATTACAGTTATCAGCAACGCCAGAGAAATAAACCAGATGATCCTAA
ACATGAGGAGGTTATTGATTGTGTGAAGAAAATAGCTGAGGCGAGCCAGTATTGTTATGGAAGTCGCAGGATGAAGAATG
CTTTAAATGCATTAGGTTATCCAGTAGGTCGAAGACGAGCTCAAAGTTTAATGAAAGAAGCCAAAGTTTTTGTTCGATAT
CGAAAGAAATATAAGGTGACTACCAATAGCAACCATAAACAATCGGTTTATGAAAATGTATTGAATAGGCAATTTCATAC
AGATAAACCTAATAAAGCCTACGTATCAGATATTACCTATATCTGGACGCAGGAAGGCGGGCTTTATTTAGCAGTCGTTC
TGGATTTATTTTCAAGGAAGGTGGTTGGTTGGAGCATGGGATCCAGAATGAAAGCAACATTGGTTTGTGATGCTCTGAAT
ATGGCAATTTGGCAGCGAAAACCTCCATCAGGGCTTATTGTTCATTCCGATAGAGGGGCTCAGTATGCTAGTTGCCAATA
CCGCAATTTATTAACGGGCAAAGGATATATTGGTAGCATGAGCAGAAAAGGTGATTGCTGGGATAACAGCGTTGTTGAAA
GCTTCTTTGGCAGCTTAAAACAAGAGCGAGTTCAGTGGCGAAATTATCAAACTCGATGGGAGGCTCAACAGGACATTTTG
AATTACATCACCATGTTCTATAACAGTCACAGATTACATTCATATTTGGGTTATTTAAGTCCAAATCAATTTGAAAAACA
GAGCGATTTTTTAATGAAAGTTGCTTAA

Upstream 100 bases:

>100_bases
AAAAGGAAATCTTAAAAAAGGCGGCGGTCTTCTTTGCTCAAGAAACGAAATAAAATATTCGTTTGTCGCCCAAAATAAGA
AGACCTGGTCGGTTGGCTTA

Downstream 100 bases:

>100_bases
CTGAGGTGTAACATTTTGGTTGACCACGTCAAAGTTAAATGGTTCATTTAAGCGGTGGTTTTTTTAAACTCAAAAACATC
CATATTGAAGTAATACAAAA

Product: integrase

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MCQLLGITRHGYYSYQQRQRNKPDDPKHEEVIDCVKKIAEASQYCYGSRRMKNALNALGYPVGRRRAQSLMKEAKVFVRY
RKKYKVTTNSNHKQSVYENVLNRQFHTDKPNKAYVSDITYIWTQEGGLYLAVVLDLFSRKVVGWSMGSRMKATLVCDALN
MAIWQRKPPSGLIVHSDRGAQYASCQYRNLLTGKGYIGSMSRKGDCWDNSVVESFFGSLKQERVQWRNYQTRWEAQQDIL
NYITMFYNSHRLHSYLGYLSPNQFEKQSDFLMKVA

Sequences:

>Translated_275_residues
MCQLLGITRHGYYSYQQRQRNKPDDPKHEEVIDCVKKIAEASQYCYGSRRMKNALNALGYPVGRRRAQSLMKEAKVFVRY
RKKYKVTTNSNHKQSVYENVLNRQFHTDKPNKAYVSDITYIWTQEGGLYLAVVLDLFSRKVVGWSMGSRMKATLVCDALN
MAIWQRKPPSGLIVHSDRGAQYASCQYRNLLTGKGYIGSMSRKGDCWDNSVVESFFGSLKQERVQWRNYQTRWEAQQDIL
NYITMFYNSHRLHSYLGYLSPNQFEKQSDFLMKVA
>Mature_275_residues
MCQLLGITRHGYYSYQQRQRNKPDDPKHEEVIDCVKKIAEASQYCYGSRRMKNALNALGYPVGRRRAQSLMKEAKVFVRY
RKKYKVTTNSNHKQSVYENVLNRQFHTDKPNKAYVSDITYIWTQEGGLYLAVVLDLFSRKVVGWSMGSRMKATLVCDALN
MAIWQRKPPSGLIVHSDRGAQYASCQYRNLLTGKGYIGSMSRKGDCWDNSVVESFFGSLKQERVQWRNYQTRWEAQQDIL
NYITMFYNSHRLHSYLGYLSPNQFEKQSDFLMKVA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=234, Percent_Identity=34.1880341880342, Blast_Score=138, Evalue=6e-33,
Organism=Escherichia coli, GI1788405, Length=269, Percent_Identity=40.8921933085502, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787263, Length=269, Percent_Identity=40.8921933085502, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786753, Length=269, Percent_Identity=40.8921933085502, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786570, Length=269, Percent_Identity=40.8921933085502, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786490, Length=269, Percent_Identity=40.8921933085502, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789981, Length=266, Percent_Identity=31.9548872180451, Blast_Score=127, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32160; Mature: 32160

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQLLGITRHGYYSYQQRQRNKPDDPKHEEVIDCVKKIAEASQYCYGSRRMKNALNALGY
CCEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVGRRRAQSLMKEAKVFVRYRKKYKVTTNSNHKQSVYENVLNRQFHTDKPNKAYVSDITY
CHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEE
IWTQEGGLYLAVVLDLFSRKVVGWSMGSRMKATLVCDALNMAIWQRKPPSGLIVHSDRGA
EEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
QYASCQYRNLLTGKGYIGSMSRKGDCWDNSVVESFFGSLKQERVQWRNYQTRWEAQQDIL
CCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
NYITMFYNSHRLHSYLGYLSPNQFEKQSDFLMKVA
HHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHEECC
>Mature Secondary Structure
MCQLLGITRHGYYSYQQRQRNKPDDPKHEEVIDCVKKIAEASQYCYGSRRMKNALNALGY
CCEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVGRRRAQSLMKEAKVFVRYRKKYKVTTNSNHKQSVYENVLNRQFHTDKPNKAYVSDITY
CHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEE
IWTQEGGLYLAVVLDLFSRKVVGWSMGSRMKATLVCDALNMAIWQRKPPSGLIVHSDRGA
EEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
QYASCQYRNLLTGKGYIGSMSRKGDCWDNSVVESFFGSLKQERVQWRNYQTRWEAQQDIL
CCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
NYITMFYNSHRLHSYLGYLSPNQFEKQSDFLMKVA
HHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]