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The map label for this gene is fabH [H]

Identifier: 148359770

GI number: 148359770

Start: 2635259

End: 2636320

Strand: Direct

Name: fabH [H]

Synonym: LPC_1695

Alternate gene names: 148359770

Gene position: 2635259-2636320 (Clockwise)

Preceding gene: 148359765

Following gene: 148359771

Centisome position: 73.68

GC content: 39.45

Gene sequence:

>1062_bases
ATGAATATTTTGAAACCTGATATACAATTTGAAATTACTGGCGCATCAAGAATTCTGCCTGCATCTGGCCCTATCACAAA
CCTGGAAATTTTAAAGAATTTTCCGAGAACTGCTGATAAACCGCAAGGTTTTCTCGAAAAATTCGCAGAAAAAATAGGCG
AAGAATTTGGCTTTCATACTCGATACTGGTGCCACAAACCCTGGGAATCACTCGATAATTCAAGAGAACTGTCTTCTGAA
TCACTAGCTATGCAAGCAGTAGATAAACTGTTAAGCCACAGTAAGTCAAAAGAGGTCGACGCATTTCTCTTGGGTTCCAC
AACTAATAAACGCTTTACTGGCTCTCAAGCAGCTGCTGTACTTGGAAACATGAAATTAAATGCGCCCGCTTACGATTTAA
AAACCGGTTGCTCCACTTCTTTATCAACCTTGCATTTTGCCTACGCATTGATGGCTTTGGGTTATCAAAAAATATTGGTT
TGTTGCTCTGAAACGCTATCCAAAGTGATTGACCCTGAAAATGAAAAAACCTGGATAGGTTTGGCTGATGGAGCTGCCTC
CTTACTTTTGGAAAAAAAGAAGGCGGGGTCTTTTACCATTGAAAAGAGTTTTTTTTCTACCGACGGTCAATACGTCAACG
CATTTACGACTCAAGGGGTATTCCCGCCAACTCATGAACAAATCGATTCGGTTGGTTATCATCTGGTGGGTGATGAAACC
CTAATGAAAGAGTTAGCCTATTCCCGATACATGCAAATGCTTGATAATTTATTGCCAACAGAAAAGGAAAAAAACGAGAT
AACATGGGTAATCCCACATCAAGTCAATCGAAAATTAGTAGACCAAGTACTTCATGAAAATCATTTAAACAACAAAACAA
TAATCTGGGATGCTGATACCATAGGCAATATAGGTGGCGCATCGATTCTTTATACATTAGCAAGAGCAGTTGAGGAAAAA
TTGTTTGACAGATCAGGAAAAATTCTCCTGATGAGTGTTGGTGGTGGTCTATCCTATGCGGGACAAGTCCTAAACTATCA
AAAAGCATCACACAGCAATTAA

Upstream 100 bases:

>100_bases
TTTTTTACGAAAAAGATAAAAATTCTTGATCTGGCAGAATAGAAAGAGTGTAATTTCAATGACAATAGTGTCACTTACCC
AGACAAGATAAGGCCACTTT

Downstream 100 bases:

>100_bases
GGTGTTTTATAGTGAAAAAAGAATATTTGCAGTGCCAGTCTCTGGTGGACGTCGTCAGGTTACGGGCTTTGCATAGCCCT
AAAAAGAAAAGCTGTACTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNILKPDIQFEITGASRILPASGPITNLEILKNFPRTADKPQGFLEKFAEKIGEEFGFHTRYWCHKPWESLDNSRELSSE
SLAMQAVDKLLSHSKSKEVDAFLLGSTTNKRFTGSQAAAVLGNMKLNAPAYDLKTGCSTSLSTLHFAYALMALGYQKILV
CCSETLSKVIDPENEKTWIGLADGAASLLLEKKKAGSFTIEKSFFSTDGQYVNAFTTQGVFPPTHEQIDSVGYHLVGDET
LMKELAYSRYMQMLDNLLPTEKEKNEITWVIPHQVNRKLVDQVLHENHLNNKTIIWDADTIGNIGGASILYTLARAVEEK
LFDRSGKILLMSVGGGLSYAGQVLNYQKASHSN

Sequences:

>Translated_353_residues
MNILKPDIQFEITGASRILPASGPITNLEILKNFPRTADKPQGFLEKFAEKIGEEFGFHTRYWCHKPWESLDNSRELSSE
SLAMQAVDKLLSHSKSKEVDAFLLGSTTNKRFTGSQAAAVLGNMKLNAPAYDLKTGCSTSLSTLHFAYALMALGYQKILV
CCSETLSKVIDPENEKTWIGLADGAASLLLEKKKAGSFTIEKSFFSTDGQYVNAFTTQGVFPPTHEQIDSVGYHLVGDET
LMKELAYSRYMQMLDNLLPTEKEKNEITWVIPHQVNRKLVDQVLHENHLNNKTIIWDADTIGNIGGASILYTLARAVEEK
LFDRSGKILLMSVGGGLSYAGQVLNYQKASHSN
>Mature_353_residues
MNILKPDIQFEITGASRILPASGPITNLEILKNFPRTADKPQGFLEKFAEKIGEEFGFHTRYWCHKPWESLDNSRELSSE
SLAMQAVDKLLSHSKSKEVDAFLLGSTTNKRFTGSQAAAVLGNMKLNAPAYDLKTGCSTSLSTLHFAYALMALGYQKILV
CCSETLSKVIDPENEKTWIGLADGAASLLLEKKKAGSFTIEKSFFSTDGQYVNAFTTQGVFPPTHEQIDSVGYHLVGDET
LMKELAYSRYMQMLDNLLPTEKEKNEITWVIPHQVNRKLVDQVLHENHLNNKTIIWDADTIGNIGGASILYTLARAVEEK
LFDRSGKILLMSVGGGLSYAGQVLNYQKASHSN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=224, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 39162; Mature: 39162

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILKPDIQFEITGASRILPASGPITNLEILKNFPRTADKPQGFLEKFAEKIGEEFGFHT
CCCCCCCCEEEECCCCEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
RYWCHKPWESLDNSRELSSESLAMQAVDKLLSHSKSKEVDAFLLGSTTNKRFTGSQAAAV
EEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHH
LGNMKLNAPAYDLKTGCSTSLSTLHFAYALMALGYQKILVCCSETLSKVIDPENEKTWIG
HCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
LADGAASLLLEKKKAGSFTIEKSFFSTDGQYVNAFTTQGVFPPTHEQIDSVGYHLVGDET
ECCCHHHHHHHHHCCCCEEEEHHHHCCCCCEEEEEECCCCCCCCHHHHHHCCCEEECCHH
LMKELAYSRYMQMLDNLLPTEKEKNEITWVIPHQVNRKLVDQVLHENHLNNKTIIWDADT
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCC
IGNIGGASILYTLARAVEEKLFDRSGKILLMSVGGGLSYAGQVLNYQKASHSN
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNILKPDIQFEITGASRILPASGPITNLEILKNFPRTADKPQGFLEKFAEKIGEEFGFHT
CCCCCCCCEEEECCCCEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
RYWCHKPWESLDNSRELSSESLAMQAVDKLLSHSKSKEVDAFLLGSTTNKRFTGSQAAAV
EEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHH
LGNMKLNAPAYDLKTGCSTSLSTLHFAYALMALGYQKILVCCSETLSKVIDPENEKTWIG
HCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
LADGAASLLLEKKKAGSFTIEKSFFSTDGQYVNAFTTQGVFPPTHEQIDSVGYHLVGDET
ECCCHHHHHHHHHCCCCEEEEHHHHCCCCCEEEEEECCCCCCCCHHHHHHCCCEEECCHH
LMKELAYSRYMQMLDNLLPTEKEKNEITWVIPHQVNRKLVDQVLHENHLNNKTIIWDADT
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCC
IGNIGGASILYTLARAVEEKLFDRSGKILLMSVGGGLSYAGQVLNYQKASHSN
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]