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The map label for this gene is dtpA [H]

Identifier: 148359738

GI number: 148359738

Start: 2597670

End: 2599151

Strand: Direct

Name: dtpA [H]

Synonym: LPC_1662

Alternate gene names: 148359738

Gene position: 2597670-2599151 (Clockwise)

Preceding gene: 148359737

Following gene: 148359746

Centisome position: 72.63

GC content: 37.11

Gene sequence:

>1482_bases
ATGCCCCATGGAGTTGCTGCGCTCTGCTTAATTCAGGCATTTTCGACTTTTTCATACGCTGTTCAATATTCTTCGCTCGC
ACTTTTTATTACCAAACAACTTGGAATTGCCAATTTATCAGCCAATAGCATAGTGGGCCTGTTTTTAAGTTTTAGCTATA
TTTTTCAACTAATTGGCGGCGTCATCGGAAGCCGTTTTATAAGTAACAGACTACTATTTGTTACAACTATTCTTATTCAA
AATATGGGTTTATTCGTTTTAGCGCAAGCAAATCCGTCCTCACTTAACATAGGCTTAAGTTTGTTTATGGTAGGTTCGGG
TTTGAATGTTACTTCCAGCAACAGCATGCTTACTCAATGTTTCATACCACAGGATGATCGCAGGGAAAGTGCATTTTTTC
TCAGTTATGCCGGCATGAATGTCGGTTATTGCATAGGTTATATAGCCTGTGGTTTTTTTGATTACTCCAACCAGTATCAA
TATTTGTTCTATGCAAGCATCCTGACTAATTCCATTGCTTTATTGATTATTATCAAAAACTGGGCCTACCTTGGCGATAA
AAATTTTCCATTACCTGATCTCACTAAACGAAACTGGTATTTCATAAAAAATATTCTGGCAATAGCATTCATTACACTCC
TTATTCCTTTTATGCGGGTATGTTTTGAGTTTGCAAACTTTTGTAATGGATTGGTAATAATTACCTGTTTATTCATGTTT
CTTATCATCTTTATCCTGGGGCTAAAACAAAAATCCTCCTCCGACAGGAAAAAAATGATGGCATATTTAATTTTGGCAAT
CAGTTCGGTTTTATTTTGGATGATTTATCTAACTGGCCCGATGGGTGTAACTCTTTTTGTCAAAAATAATGTGGATAAGC
ATCTTTTCAGCTTTGAATTGGCTACTCAATGGATAAAAAATATTAATCCCGTGGTCATTATTTTAGGAGCTCCAATCATG
GCCATGCTCATTAACAAATTAAAAGCAAAAGGTTTTCATGTCTCTGTTCCTGTGCAATTTTCCTGTTCCTTCGTGTTTTT
AGCCCTGTCCTTTTTATGTCTTATCTTTGGAATTATTTGTTCAAATTCCTATGGGTATATCAGCGTATACTGGATCATAG
GCCATCATATCTTGCAAGGAATGTCTGAGTTGCTTCTTGGTCCTGTTGGCTATGCGTTAATTGGAAGAATAGCTCCCCCA
AAACTACAAGGGATTTTAATGGGCACCTGGATGTTGGTTACAGGTGTCGCAGCCTCTTTTTCCCAATATTTCTCCAATGC
CATGGTGCAATCAGAATCTGTAGACCCCCTAATTACAAATCAGGATTTTCTAAGGGCATTTAAGCAATTGGGACTTTGGT
CTTTACTCTGCGCTGTCTTGTTATATTTTGTTTCAGGTAAAATAACCAAAATAATCAATGGGGTACAAGACAATAAACCT
GTCAATCAGAGCAAGGCTATCCCAATACCTTACTCCAACTAA

Upstream 100 bases:

>100_bases
ATGGCAGGTTGTTACATTCTTGAAGGCAAATGATTATTGATGGTAAAGTCTATTCTCATAAAATCAGCCAAAATGTTTGA
TGATTAAAATAATTCGGGAA

Downstream 100 bases:

>100_bases
TCATTTAAAAATCCAGAGTATTGCTTTGCTCATCGGGTTCTTCCAGACTTTTAGCAACATCCAGGTAAATTTTCGGATTG
TACTGGTACAAACGGAAGAA

Product: POT family transporter peptide transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLLFVTTILIQ
NMGLFVLAQANPSSLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQ
YLFYASILTNSIALLIIIKNWAYLGDKNFPLPDLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVVIILGAPIM
AMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIICSNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPP
KLQGILMGTWMLVTGVAASFSQYFSNAMVQSESVDPLITNQDFLRAFKQLGLWSLLCAVLLYFVSGKITKIINGVQDNKP
VNQSKAIPIPYSN

Sequences:

>Translated_493_residues
MPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLLFVTTILIQ
NMGLFVLAQANPSSLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQ
YLFYASILTNSIALLIIIKNWAYLGDKNFPLPDLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVVIILGAPIM
AMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIICSNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPP
KLQGILMGTWMLVTGVAASFSQYFSNAMVQSESVDPLITNQDFLRAFKQLGLWSLLCAVLLYFVSGKITKIINGVQDNKP
VNQSKAIPIPYSN
>Mature_492_residues
PHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLLFVTTILIQN
MGLFVLAQANPSSLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQY
LFYASILTNSIALLIIIKNWAYLGDKNFPLPDLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMFL
IIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVVIILGAPIMA
MLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIICSNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPPK
LQGILMGTWMLVTGVAASFSQYFSNAMVQSESVDPLITNQDFLRAFKQLGLWSLLCAVLLYFVSGKITKIINGVQDNKPV
NQSKAIPIPYSN

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=477, Percent_Identity=25.9958071278826, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789911, Length=477, Percent_Identity=25.7861635220126, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1790572, Length=475, Percent_Identity=25.6842105263158, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786927, Length=432, Percent_Identity=23.8425925925926, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54840; Mature: 54709

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIGSRFISNRLLFVTTILIQNMGLFVLAQANPSSLNIGLSLFMVGSGLNVTSSNSMLTQC
HHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCCCEEECEEEEEEECCCCCCCCCCEEEEE
FIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQYLFYASILTNSIALLIIIKN
ECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEHEEHHHHHHCCCEEEEEEEC
WAYLGDKNFPLPDLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFEL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
ATQWIKNINPVVIILGAPIMAMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIIC
HHHHHHCCCCEEEEECHHHHHHHHHHHHCCCEEEEEEHEECHHHHHHHHHHHHHHHHHHH
SNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPPKLQGILMGTWMLVTGVAASF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SQYFSNAMVQSESVDPLITNQDFLRAFKQLGLWSLLCAVLLYFVSGKITKIINGVQDNKP
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
VNQSKAIPIPYSN
CCCCCCCCCCCCC
>Mature Secondary Structure 
PHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGG
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIGSRFISNRLLFVTTILIQNMGLFVLAQANPSSLNIGLSLFMVGSGLNVTSSNSMLTQC
HHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCCCEEECEEEEEEECCCCCCCCCCEEEEE
FIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQYLFYASILTNSIALLIIIKN
ECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEHEEHHHHHHCCCEEEEEEEC
WAYLGDKNFPLPDLTKRNWYFIKNILAIAFITLLIPFMRVCFEFANFCNGLVIITCLFMF
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFEL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
ATQWIKNINPVVIILGAPIMAMLINKLKAKGFHVSVPVQFSCSFVFLALSFLCLIFGIIC
HHHHHHCCCCEEEEECHHHHHHHHHHHHCCCEEEEEEHEECHHHHHHHHHHHHHHHHHHH
SNSYGYISVYWIIGHHILQGMSELLLGPVGYALIGRIAPPKLQGILMGTWMLVTGVAASF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SQYFSNAMVQSESVDPLITNQDFLRAFKQLGLWSLLCAVLLYFVSGKITKIINGVQDNKP
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
VNQSKAIPIPYSN
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]