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The map label for this gene is arcB [H]

Identifier: 148359718

GI number: 148359718

Start: 2563933

End: 2565963

Strand: Direct

Name: arcB [H]

Synonym: LPC_1640

Alternate gene names: 148359718

Gene position: 2563933-2565963 (Clockwise)

Preceding gene: 148359717

Following gene: 148359719

Centisome position: 71.69

GC content: 35.25

Gene sequence:

>2031_bases
ATGAGATCACAAACCATTCGTTTGACTCAGAAAGATTTTCCCATTTTTGGAAAAGCATTTTCATTAGTTAACATTTCATT
TCTCGTAATCAACGAGAATATGGAATTGGAATATATTAATGATACTGCAAAGAAAAAACTTAAAATTAATTGGAGCTCAA
CCGATAGAAAATCTTTTTTCCAATTATGGGAATTAGCCAATCTAACTCCAATCCTGACTAAAAAAGGCGATCTTATTCCT
AACAAAATTTTACAAGTGGGGAGTTATTCTATTCAATGGCAAAAAACAGTCGCAATAGTCAACGAAAAACATTACATTTT
GTTAATGGACAAAGATATTGCAACAACCTCACATCTTTTCGAAGAAATCGGGACTGCTATCTATGGTGAAATAGGATACG
CACCTAAAAACAAAATTTCTGTAAAAGAATATATTCAAGAATTAACCAACTATTACACCTCCGTTATTGATAAAATTCCT
TGTTATGTTTACTGGAAAAACACCAGTTTTGAATACATGGGTTGCAATGAAATGGCAGCGAAGTTTTTTGGCTTTAAATC
AACATCAGATATTATTGGAAAAAATGATTTTGATCTTTTTCAAGATCCTGATTTCGCTAAAAATTATCAGGAGCAAGATA
AACAAGTATTTTCAACCGGCGAACCTATTTTAAAAATGCCATCTGATCTCAAAGACCGCAATGGAATGGTCACTAATACA
TTAGTCAGCAAAGTACCCATAACTAATTTATCGGGAAGCATAGTAGGGCTTGTGGGAATTACTGTTGATGTAACTGAATT
GACAAAAGCAAAAGAAGCTGCTGAAGCAGCTAACCAAGCCAAAACTGCTTTTATTGCCAATATGAGTCATGACATCCGCA
CACCACTTACAGGGGTTATTGGAATGTCTGAATTATTGGAAAATACAGTGAAAGACCCAGAGCAAAAGGAAGAAGCACAC
ATGCTTCACGATAGCGGTGAAGAACTATTAAATATGTTAAACGATATTCTGGATGATGTTCATGCTGGCTTTATGGATAA
AGAAGATATCCGCATAGAAACTTTTGATTTGTATCAATGTATTGAAGATCTGGTGAAACTCGAACGCCCTACTACAGTAA
TGAAACATTTGGAATTAATTGTGCATATTGGTAAATCTGTACCTCGTTATATCCAGAGTGATCGTAAAAAAATTCATCGA
GTTCTTTTAAATTTATTGGGCAATGCGATTAAATTTACCCCTAAAGGTCAGATTACGATCCAAGTAGCATGCCTTGAAGT
TTCAGGAAAAAACATTCATTTGCAATTTAAAGTCAGCGATACGGGGATAGGTATTCCAACCAGTCTTCAAGAAAAAGTGT
TTGAGCGTTTTTTCCGAATCAGTCCCTCTTATAAAGGGATTTATAAAGGACATGGTCTTGGCTTACATATCGCACAATCG
TATGTCAACTTATTAGGGGGCCATATTGCTTTAATAAGCGAAGAAGGCAAAGGAACCACTTTTTATTTCGATATTCCATG
CCAAACAGGCACGCAGAAAAAAATAAAAACCAATAAGTTAACGAACAGTTCAAAAAAGATTGACTCCTCGCTCTCCACCT
CATCTAACTCCCAATTAACTCCCAAGTTGTCATCCAAAACTGAAGAAAATTCGCCCTACGTATTGTTAGTGGAAGACAAC
AACATTGCATTGAAAGTGCTGGAGCTTATTTTATCAAATGAAGGTTATCGCTTTAAATCTGCTTCTAATGGAGAAGAAGC
ATTGGCATTAATTCAAACCGAATCGTTTGACCTTGTCATCACAGATCTTGGCCTTCCAGGAATATCTGGTTGTGAACTTT
CTGTTAAAATTCGTGAATGGGAAAAAAAACATTCCAAAAAACCTCTTCCTGTTATTGGATTGACTGGACATACTAAAGAT
TCCTCTGAAAAAGGATGCCTCGCGTCTGGTATGAATAATGTGTTCACTAAACCTGTAACTCCAGAGCTAATTCGCAATAT
AATCAATAAGTATCTATTAGGAGAAAAATAA

Upstream 100 bases:

>100_bases
GGCAAATTATCTGCCATACTATAGAAGCGAATCACGATACAATCATTCGTCAGGGATATCAATTTATTGCGCAAAAGTTA
ATTGAGTACAGGGACATTGA

Downstream 100 bases:

>100_bases
AAGAAAAACTCGGTTAATTTAAAATTCACTTGATTCATATAATAAATAAGCAAACTACCCAAGCGAACCCTTCTAATATA
GCGAATTAATTAAAGAGACA

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MRSQTIRLTQKDFPIFGKAFSLVNISFLVINENMELEYINDTAKKKLKINWSSTDRKSFFQLWELANLTPILTKKGDLIP
NKILQVGSYSIQWQKTVAIVNEKHYILLMDKDIATTSHLFEEIGTAIYGEIGYAPKNKISVKEYIQELTNYYTSVIDKIP
CYVYWKNTSFEYMGCNEMAAKFFGFKSTSDIIGKNDFDLFQDPDFAKNYQEQDKQVFSTGEPILKMPSDLKDRNGMVTNT
LVSKVPITNLSGSIVGLVGITVDVTELTKAKEAAEAANQAKTAFIANMSHDIRTPLTGVIGMSELLENTVKDPEQKEEAH
MLHDSGEELLNMLNDILDDVHAGFMDKEDIRIETFDLYQCIEDLVKLERPTTVMKHLELIVHIGKSVPRYIQSDRKKIHR
VLLNLLGNAIKFTPKGQITIQVACLEVSGKNIHLQFKVSDTGIGIPTSLQEKVFERFFRISPSYKGIYKGHGLGLHIAQS
YVNLLGGHIALISEEGKGTTFYFDIPCQTGTQKKIKTNKLTNSSKKIDSSLSTSSNSQLTPKLSSKTEENSPYVLLVEDN
NIALKVLELILSNEGYRFKSASNGEEALALIQTESFDLVITDLGLPGISGCELSVKIREWEKKHSKKPLPVIGLTGHTKD
SSEKGCLASGMNNVFTKPVTPELIRNIINKYLLGEK

Sequences:

>Translated_676_residues
MRSQTIRLTQKDFPIFGKAFSLVNISFLVINENMELEYINDTAKKKLKINWSSTDRKSFFQLWELANLTPILTKKGDLIP
NKILQVGSYSIQWQKTVAIVNEKHYILLMDKDIATTSHLFEEIGTAIYGEIGYAPKNKISVKEYIQELTNYYTSVIDKIP
CYVYWKNTSFEYMGCNEMAAKFFGFKSTSDIIGKNDFDLFQDPDFAKNYQEQDKQVFSTGEPILKMPSDLKDRNGMVTNT
LVSKVPITNLSGSIVGLVGITVDVTELTKAKEAAEAANQAKTAFIANMSHDIRTPLTGVIGMSELLENTVKDPEQKEEAH
MLHDSGEELLNMLNDILDDVHAGFMDKEDIRIETFDLYQCIEDLVKLERPTTVMKHLELIVHIGKSVPRYIQSDRKKIHR
VLLNLLGNAIKFTPKGQITIQVACLEVSGKNIHLQFKVSDTGIGIPTSLQEKVFERFFRISPSYKGIYKGHGLGLHIAQS
YVNLLGGHIALISEEGKGTTFYFDIPCQTGTQKKIKTNKLTNSSKKIDSSLSTSSNSQLTPKLSSKTEENSPYVLLVEDN
NIALKVLELILSNEGYRFKSASNGEEALALIQTESFDLVITDLGLPGISGCELSVKIREWEKKHSKKPLPVIGLTGHTKD
SSEKGCLASGMNNVFTKPVTPELIRNIINKYLLGEK
>Mature_676_residues
MRSQTIRLTQKDFPIFGKAFSLVNISFLVINENMELEYINDTAKKKLKINWSSTDRKSFFQLWELANLTPILTKKGDLIP
NKILQVGSYSIQWQKTVAIVNEKHYILLMDKDIATTSHLFEEIGTAIYGEIGYAPKNKISVKEYIQELTNYYTSVIDKIP
CYVYWKNTSFEYMGCNEMAAKFFGFKSTSDIIGKNDFDLFQDPDFAKNYQEQDKQVFSTGEPILKMPSDLKDRNGMVTNT
LVSKVPITNLSGSIVGLVGITVDVTELTKAKEAAEAANQAKTAFIANMSHDIRTPLTGVIGMSELLENTVKDPEQKEEAH
MLHDSGEELLNMLNDILDDVHAGFMDKEDIRIETFDLYQCIEDLVKLERPTTVMKHLELIVHIGKSVPRYIQSDRKKIHR
VLLNLLGNAIKFTPKGQITIQVACLEVSGKNIHLQFKVSDTGIGIPTSLQEKVFERFFRISPSYKGIYKGHGLGLHIAQS
YVNLLGGHIALISEEGKGTTFYFDIPCQTGTQKKIKTNKLTNSSKKIDSSLSTSSNSQLTPKLSSKTEENSPYVLLVEDN
NIALKVLELILSNEGYRFKSASNGEEALALIQTESFDLVITDLGLPGISGCELSVKIREWEKKHSKKPLPVIGLTGHTKD
SSEKGCLASGMNNVFTKPVTPELIRNIINKYLLGEK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=585, Percent_Identity=28.3760683760684, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI87081816, Length=412, Percent_Identity=28.3980582524272, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=37.4485596707819, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1788713, Length=435, Percent_Identity=27.1264367816092, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=32.5581395348837, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=26.3940520446097, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=269, Percent_Identity=28.996282527881, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=384, Percent_Identity=23.6979166666667, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=27.3092369477912, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=27.9352226720648, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=25.5605381165919, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75813; Mature: 75813

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSQTIRLTQKDFPIFGKAFSLVNISFLVINENMELEYINDTAKKKLKINWSSTDRKSFF
CCCCEEEEECCCCCCHHHHHHEEEEEEEEEECCCEEEEECCCCCCEEEEEECCCCHHHHH
QLWELANLTPILTKKGDLIPNKILQVGSYSIQWQKTVAIVNEKHYILLMDKDIATTSHLF
HHHHHCCCCEEECCCCCCCHHHHHHHCCCEEEEEEEEEEECCCEEEEEECCCCHHHHHHH
EEIGTAIYGEIGYAPKNKISVKEYIQELTNYYTSVIDKIPCYVYWKNTSFEYMGCNEMAA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCHHHHH
KFFGFKSTSDIIGKNDFDLFQDPDFAKNYQEQDKQVFSTGEPILKMPSDLKDRNGMVTNT
HHHCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHH
LVSKVPITNLSGSIVGLVGITVDVTELTKAKEAAEAANQAKTAFIANMSHDIRTPLTGVI
HHHHCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCHHCCCHHHHH
GMSELLENTVKDPEQKEEAHMLHDSGEELLNMLNDILDDVHAGFMDKEDIRIETFDLYQC
HHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHH
IEDLVKLERPTTVMKHLELIVHIGKSVPRYIQSDRKKIHRVLLNLLGNAIKFTPKGQITI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEE
QVACLEVSGKNIHLQFKVSDTGIGIPTSLQEKVFERFFRISPSYKGIYKGHGLGLHIAQS
EEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHH
YVNLLGGHIALISEEGKGTTFYFDIPCQTGTQKKIKTNKLTNSSKKIDSSLSTSSNSQLT
HHHHHCCEEEEEEECCCCEEEEEECCCCCCCCCHHEHHHCCCCHHHHHHHCCCCCCCCCC
PKLSSKTEENSPYVLLVEDNNIALKVLELILSNEGYRFKSASNGEEALALIQTESFDLVI
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEECCCEEEE
TDLGLPGISGCELSVKIREWEKKHSKKPLPVIGLTGHTKDSSEKGCLASGMNNVFTKPVT
EECCCCCCCCCEEEEEHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCHHHCCCCCC
PELIRNIINKYLLGEK
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSQTIRLTQKDFPIFGKAFSLVNISFLVINENMELEYINDTAKKKLKINWSSTDRKSFF
CCCCEEEEECCCCCCHHHHHHEEEEEEEEEECCCEEEEECCCCCCEEEEEECCCCHHHHH
QLWELANLTPILTKKGDLIPNKILQVGSYSIQWQKTVAIVNEKHYILLMDKDIATTSHLF
HHHHHCCCCEEECCCCCCCHHHHHHHCCCEEEEEEEEEEECCCEEEEEECCCCHHHHHHH
EEIGTAIYGEIGYAPKNKISVKEYIQELTNYYTSVIDKIPCYVYWKNTSFEYMGCNEMAA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCHHHHH
KFFGFKSTSDIIGKNDFDLFQDPDFAKNYQEQDKQVFSTGEPILKMPSDLKDRNGMVTNT
HHHCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHH
LVSKVPITNLSGSIVGLVGITVDVTELTKAKEAAEAANQAKTAFIANMSHDIRTPLTGVI
HHHHCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCHHCCCHHHHH
GMSELLENTVKDPEQKEEAHMLHDSGEELLNMLNDILDDVHAGFMDKEDIRIETFDLYQC
HHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHH
IEDLVKLERPTTVMKHLELIVHIGKSVPRYIQSDRKKIHRVLLNLLGNAIKFTPKGQITI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEE
QVACLEVSGKNIHLQFKVSDTGIGIPTSLQEKVFERFFRISPSYKGIYKGHGLGLHIAQS
EEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHH
YVNLLGGHIALISEEGKGTTFYFDIPCQTGTQKKIKTNKLTNSSKKIDSSLSTSSNSQLT
HHHHHCCEEEEEEECCCCEEEEEECCCCCCCCCHHEHHHCCCCHHHHHHHCCCCCCCCCC
PKLSSKTEENSPYVLLVEDNNIALKVLELILSNEGYRFKSASNGEEALALIQTESFDLVI
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEECCCEEEE
TDLGLPGISGCELSVKIREWEKKHSKKPLPVIGLTGHTKDSSEKGCLASGMNNVFTKPVT
EECCCCCCCCCEEEEEHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCHHHCCCCCC
PELIRNIINKYLLGEK
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]