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The map label for this gene is mltA [H]

Identifier: 148359565

GI number: 148359565

Start: 2349245

End: 2350441

Strand: Reverse

Name: mltA [H]

Synonym: LPC_1477

Alternate gene names: 148359565

Gene position: 2350441-2349245 (Counterclockwise)

Preceding gene: 148359566

Following gene: 148359563

Centisome position: 65.72

GC content: 38.6

Gene sequence:

>1197_bases
ATGAAATCGAAATTAATTTATCTGACAGTAGCCTTGGCTGCAATTATCTTAAGCGCAGCAGTATGGTGGTGGTTGCAATC
TCCCAAGCCAACTTTCAGGCAGGTAAGCTTTAAGCATTTACCTGGGTGGGAGAATGCACAACTTAAAAAATCGTTAGAAA
CTTTTCAAACATCTTGTCGAGCCTTTCTAAAACAAAATCCTGAACGTGTTGTTGGCACAGAGCAGATTGATTTACAGGCA
AAAGATTGGCATCCAGCCTGTCGTGCTGCTTTAAAAATAAATCCTGTTGATGAACAGTCAGCAAAATTATTTTTTGAGAA
GTGGTTTGCCCCTGTGGAATTCTATGATGATAAACCAGTTAAAGGTTTATTTACGGGCTATTATATGCCTTTAATTAAAG
GCAGTTATAACAAATCAGATGAATTTAGTGTTCCTATTTATGAATTACCCAGTAACTTAGTAACTGTTGATTTGGGTTTA
TTTCTTCCTAATTTAAAAAACAAGAAAATCATTGGACGAATTGCAGGTAATAAAGTCGTACCATTTTACACTCGAGAGCA
AATTAATAAAGGGGCAATTAAAGACACAGCTCGTGTTTTGGTCTGGATCAATAGTCCTGTTGACAGGTTATTTTTAGAAA
TTCAGGGCTCAGGAATCATTGAGCTTGAGGATGGTAAACGAATTTTTATAGGCTATGACGGTCAAAATGGTGCCCCCTAT
ACTGCCATTGCTGGAGTATTAATTAAAAAGGGTATTATGACCAAGCACAATGCTTCCATGCAAAGGATTAAAAAATATCT
GGAAGCTCATCCCAAGCAAATGGATAAAATAATCAATCAAAATAAATCATTTGTTTTTTTCCGCAAGTTGTCATTAGAAG
CGGCTTTAGGTTCACAGGGTGTGGCATTAACACCCGGTTATTCTCTTGCTATTGATAAACAATGGATACCAATGGGAGCG
CCTCTATGGTTAAACACTACAAGACCAGATAGTAAAAATCCTGACGTCAATAAACCTATGCAACGTTTGATGATAGCTCA
AGACACTGGTGGCGCTATTCGTGGTAAAGTAAGAGGTGATGTATTTTGGGGTGGTGGTGACAAAGCCACTTTGATTGCTG
GCCATATGAAGAACGAGGGGCATTATTGGCTTCTTCTGCCGGCTCATGCATTATCGCGCTTGGCACAGTTGAAGTAG

Upstream 100 bases:

>100_bases
AAAAAAGCTATTATAACTGGATGTTTTTTGTAGTAAGATGGACTAATAGCAATAATTTTTAGTTGCATTTTTCTCCATCA
CGTGTAAAAATTGACCTCCT

Downstream 100 bases:

>100_bases
GGGTGTAAGTCCTGTCTTTGCAATTTTTTATTTGGCTATTGGGATTCACCAGTCCTGTGATAATGAATCCCCGATAGCAT
TGTAAATCATTTGTTTCAAG

Product: hypothetical protein

Products: Muramic Acid Residue [C]

Alternate protein names: Murein hydrolase A [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKSKLIYLTVALAAIILSAAVWWWLQSPKPTFRQVSFKHLPGWENAQLKKSLETFQTSCRAFLKQNPERVVGTEQIDLQA
KDWHPACRAALKINPVDEQSAKLFFEKWFAPVEFYDDKPVKGLFTGYYMPLIKGSYNKSDEFSVPIYELPSNLVTVDLGL
FLPNLKNKKIIGRIAGNKVVPFYTREQINKGAIKDTARVLVWINSPVDRLFLEIQGSGIIELEDGKRIFIGYDGQNGAPY
TAIAGVLIKKGIMTKHNASMQRIKKYLEAHPKQMDKIINQNKSFVFFRKLSLEAALGSQGVALTPGYSLAIDKQWIPMGA
PLWLNTTRPDSKNPDVNKPMQRLMIAQDTGGAIRGKVRGDVFWGGGDKATLIAGHMKNEGHYWLLLPAHALSRLAQLK

Sequences:

>Translated_398_residues
MKSKLIYLTVALAAIILSAAVWWWLQSPKPTFRQVSFKHLPGWENAQLKKSLETFQTSCRAFLKQNPERVVGTEQIDLQA
KDWHPACRAALKINPVDEQSAKLFFEKWFAPVEFYDDKPVKGLFTGYYMPLIKGSYNKSDEFSVPIYELPSNLVTVDLGL
FLPNLKNKKIIGRIAGNKVVPFYTREQINKGAIKDTARVLVWINSPVDRLFLEIQGSGIIELEDGKRIFIGYDGQNGAPY
TAIAGVLIKKGIMTKHNASMQRIKKYLEAHPKQMDKIINQNKSFVFFRKLSLEAALGSQGVALTPGYSLAIDKQWIPMGA
PLWLNTTRPDSKNPDVNKPMQRLMIAQDTGGAIRGKVRGDVFWGGGDKATLIAGHMKNEGHYWLLLPAHALSRLAQLK
>Mature_398_residues
MKSKLIYLTVALAAIILSAAVWWWLQSPKPTFRQVSFKHLPGWENAQLKKSLETFQTSCRAFLKQNPERVVGTEQIDLQA
KDWHPACRAALKINPVDEQSAKLFFEKWFAPVEFYDDKPVKGLFTGYYMPLIKGSYNKSDEFSVPIYELPSNLVTVDLGL
FLPNLKNKKIIGRIAGNKVVPFYTREQINKGAIKDTARVLVWINSPVDRLFLEIQGSGIIELEDGKRIFIGYDGQNGAPY
TAIAGVLIKKGIMTKHNASMQRIKKYLEAHPKQMDKIINQNKSFVFFRKLSLEAALGSQGVALTPGYSLAIDKQWIPMGA
PLWLNTTRPDSKNPDVNKPMQRLMIAQDTGGAIRGKVRGDVFWGGGDKATLIAGHMKNEGHYWLLLPAHALSRLAQLK

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Note=In closely related bacteria this protein is attached to the outer membrane by a lipid anchor. This is apparently not the case here [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=267, Percent_Identity=32.9588014981273, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 44769; Mature: 44769

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKLIYLTVALAAIILSAAVWWWLQSPKPTFRQVSFKHLPGWENAQLKKSLETFQTSCR
CCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCHHHHHHHHHHHHHHH
AFLKQNPERVVGTEQIDLQAKDWHPACRAALKINPVDEQSAKLFFEKWFAPVEFYDDKPV
HHHHCCCCCCCCCEEEEEEECCCCHHHHEEEEECCCCCHHHHHHHHHHCCCEEECCCCCC
KGLFTGYYMPLIKGSYNKSDEFSVPIYELPSNLVTVDLGLFLPNLKNKKIIGRIAGNKVV
CHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEEEHCCCCCCCCEEEEEECCCEEE
PFYTREQINKGAIKDTARVLVWINSPVDRLFLEIQGSGIIELEDGKRIFIGYDGQNGAPY
EEHHHHHCCCCCCCCCEEEEEEECCCHHEEEEEECCCEEEEEECCCEEEEEECCCCCCCH
TAIAGVLIKKGIMTKHNASMQRIKKYLEAHPKQMDKIINQNKSFVFFRKLSLEAALGSQG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEEEHHHHCCCCC
VALTPGYSLAIDKQWIPMGAPLWLNTTRPDSKNPDVNKPMQRLMIAQDTGGAIRGKVRGD
EEECCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHEEEECCCCEEEEEEEEE
VFWGGGDKATLIAGHMKNEGHYWLLLPAHALSRLAQLK
EEECCCCCEEEEEEEECCCCCEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MKSKLIYLTVALAAIILSAAVWWWLQSPKPTFRQVSFKHLPGWENAQLKKSLETFQTSCR
CCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCHHHHHHHHHHHHHHH
AFLKQNPERVVGTEQIDLQAKDWHPACRAALKINPVDEQSAKLFFEKWFAPVEFYDDKPV
HHHHCCCCCCCCCEEEEEEECCCCHHHHEEEEECCCCCHHHHHHHHHHCCCEEECCCCCC
KGLFTGYYMPLIKGSYNKSDEFSVPIYELPSNLVTVDLGLFLPNLKNKKIIGRIAGNKVV
CHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEEEHCCCCCCCCEEEEEECCCEEE
PFYTREQINKGAIKDTARVLVWINSPVDRLFLEIQGSGIIELEDGKRIFIGYDGQNGAPY
EEHHHHHCCCCCCCCCEEEEEEECCCHHEEEEEECCCEEEEEECCCEEEEEECCCCCCCH
TAIAGVLIKKGIMTKHNASMQRIKKYLEAHPKQMDKIINQNKSFVFFRKLSLEAALGSQG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEEEHHHHCCCCC
VALTPGYSLAIDKQWIPMGAPLWLNTTRPDSKNPDVNKPMQRLMIAQDTGGAIRGKVRGD
EEECCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHEEEECCCCEEEEEEEEE
VFWGGGDKATLIAGHMKNEGHYWLLLPAHALSRLAQLK
EEECCCCCEEEEEEEECCCCCEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]